Multiparametrik prostat manyetik rezonans görüntülemede farklı PI-RADS sistemlerinde okuyucular arası uyum: PI-RADSv2 ve v2.1’in bire bir karşılaştırılması

Year 2021, , 1 - 6, 30.01.2021

Mehmet Coskun , Merve Horoz , Kazım Ayberk Sinci Kürşad Dönmez Engin Uluç

https://doi.org/10.16899/jcm.836867

Cited By: 4

Abstract

Amaç
Bu yazının amacı, okuyucular arası uyum ve klinik anlamlı prostat kanseri (KAK) tespitinde tanısal performans açısından PI-RADSv2 ile v2.1’in karşılaştırılmasıdır.
Gereç ve Yöntem
Multiparametrik prostat manyetik rezonans görüntüleme (mpMRG) ve 12 kadran sistematik biyopsi yapılan 202 olgu, bu retrospektif çalışmayı oluşturmaktadır. Görüntüleme parametrelerinde PI-RADSv2 ve v2.1’in sunduğu tüm önerilere uyuldu. mpMRG’ler iki radyolog tarafından ayrı ayrı değerlendirildi. Sistemlerin tanısal performansını belirlemede indeks lezyon esas alındı. Gleason ≥ 3+4 tümörler KAK kabul edildi. Okuyucular arası uyumun belirlenmesinde kappa istatistiği kullanıldı. KAK tespitinde eğrinin altındaki alan (EAA), alıcı işletim karakteristiği eğrisi kullanılarak hesaplandı.
Bulgular
PI-RADSv2 ve v2.1 için skoru 1’den 5’e olan olgu sayısı okuyucu 1 için sırasıyla 46, 21, 13, 41, 81 ve 46, 26, 9, 43, 78 iken, okuyucu 2 için sırasıyla 46, 21, 13, 41, 81 ve 46, 26, 9, 43, 78 idi. Her iki skorlama sistemi için iki okuyucu arasındaki uyum “iyi” düzeydeydi. Kappa değerleri PI-RADSv2 için 0,600, PI-RADSv2.1 için 0,624 idi. Doksan-sekiz (%48,5) olguda KAK görüldü. PI-RADSv2 ve v2.1 skorlama sistemi için EAA değerleri okuyucu 1 için sırasıyla 0,861 ve 0,851, okuyucu 2 için sırasıyla 0,873 ve 0,883 idi.
Sonuç
Okuyucular arası uyum mpMRG’de “iyi” olup PI-RADSv2.1 ile hafif artmıştır. Her iki sistemin tanısal performansı neredeyse eşittir.

Keywords

Gleason, görüntüleme eşliğinde biyopsi, multiparametrik MRG, prostat kanseri

Supporting Institution

yok

Project Number

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Thanks

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Interreader agreement in different PI-RADS systems in multiparametric prostate magnetic resonance imaging: A head-to-head comparison between PI-RADSv2 and v2.1

Abstract

Aim
The purpose of this study is to compare PI-RADSv2 with v2.1 in terms of interreader agreement and diagnostic performance in clinically significant prostate cancer (CSCa) detection.
Materials and Methods
Two hundred-two patients who had both multiparametric prostate magnetic resonance imaging (mpMRI) and 12 quadrant systematic biopsies were included in this retrospective study. Acquisition parameters were totally complied with proposal of PI-RADSv2 and 2.1 guidelines. mpMRIs were evaluated by two radiologists independently. Index lesion’s score was used to determine diagnostic performance of the systems. Gleason ≥ 3+4 tumors were considered CSCa. Kappa statistic was used to determine interreader agreement. Area under the curve (AUC) was calculated in detection of CSCa using receiver operating characteristic curve (ROC).
Results
The numbers of cases with PI-RADSv2 and v2.1 scores from 1 to 5 were 46, 21, 13, 41, 81 and 46, 26, 9, 43, 78, by reader 1 and 51, 10, 18, 43, 80 and 51, 15, 19, 37, 80 by reader 2, respectively. There was “substantial” agreement between two readers for both scoring systems. Kappa values were 0.600 in PI-RADSv2 and 0.624 in PI-RADSv2.1. Ninety-eight (48.5%) patients had CSCa. AUC values of PI-RADSv2 and v2.1 scoring systems were 0.861 and 0.851 for reader 1, 0.873 and 0.883 for reader 2, respectively.
Conclusion
Interreader agreement was “substantial” in mpMRI and slightly improved with PI-RADSv2.1. Diagnostic performance of the two systems were almost equal.

Keywords

Gleason, image-guided biopsy, multiparametric MRI, prostate cancer

Project Number

yok

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