SARS-CoV 2 in Cellular Level: Do we dominate the whole picture and how can we intervene?

Year 2021, , 248 - 253, 25.03.2021

Muhammed Emin , Aydın Balcı , Elif Menekşe

https://doi.org/10.16899/jcm.839810

Abstract

Coronaviruses are a family of viruses present in various animals, and alpha and beta types can infect humans. Human coronavirus varieties settle in different regions of the respiratory tract epithelium, causing disease with varying severity. We conducted a comprehensive academic search to aggregate data and added our own ideas to create a good research article. As a result of many studies carried out in a short time, detailed information was obtained about the entry of the virus into the cell and its cellular cycle.
Although vaccination studies are about to come to an end, we do not yet have an agent that provides a definitive treatment that will facilitate millions of people's lives. At this point, humanity needs detailed genetic research, especially on cellular interactions.
Because although we think that we are in control of the subject, science is a field that changes daily, and new data are added to it. It is evident that we need marginal ideas for a virus that has affected the whole world, can easily be transmitted by respiratory and droplets, and has destroyed everyday life. This research aims to examine the data we have so far in detail on all of the topics we have mentioned and try to make some suggestions within our knowledge.

Keywords

SARS-CoV 2, COVID-19, Coronavirus

Hücresel Düzeyde SARS-CoV 2: Resmin tamamına hakim miyiz ve nasıl müdahale edebiliriz?

Abstract

Koronavirüsler, çeşitli hayvanlarda bulunan bir virüs ailesidir ve alfa ve beta türleri insanları enfekte edebilir. İnsan koronavirüs çeşitleri, solunum yolu epitelinin farklı bölgelerine yerleşerek değişen şiddette hastalığa neden olur. Verileri toplamak için kapsamlı bir akademik araştırma yaptık ve iyi bir araştırma makalesi oluşturmak için kendi fikirlerimizi ekledik. Kısa sürede yapılan birçok çalışma sonucunda virüsün hücreye girişi ve hücresel döngüsü hakkında detaylı bilgiler elde edildi. Aşılama çalışmaları bitmek üzere olsa da henüz milyonlarca insanın hayatını kolaylaştıracak kesin tedavi sağlayacak bir ajana sahip değiliz. Bu noktada insanlığın özellikle hücresel etkileşimler konusunda detaylı genetik araştırmalara ihtiyacı var. Çünkü konunun kontrolünde olduğumuzu düşünsek de bilim her geçen gün değişen bir alan ve ona yeni veriler ekleniyor. Tüm dünyayı etkilemiş, solunum ve damlacıklarla kolaylıkla bulaşabilen ve günlük yaşamı mahvetmiş bir virüs için marjinal fikirlere ihtiyacımız olduğu aşikardır. Bu araştırma, bahsettiğimiz tüm konularda bugüne kadar sahip olduğumuz verileri detaylı bir şekilde incelemeyi ve bilgimiz dahilinde bazı önerilerde bulunmayı amaçlamaktadır.

Keywords

SARS-CoV 2, COVID-19, Koronavirüs

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