The Relationship Between Colorectal Cancer and Abdominal Adipose Tissue Distribution

Year 2021, , 288 - 293, 24.05.2021

Fatma Esra Bahadır Ülger , Ümit Akyüz

https://doi.org/10.16899/jcm.879490

Abstract

Aim: To examine the relationship between obesity and the subcutaneous, visceral and retroperitoneal adipose tissue thicknesses of the abdomen.
Materials and Methods: The study included 62 control and 68 colorectal cancer patients. Abdominal computed tomography of the patients, which were taken within the last 6 months before preoperative or colonoscopic examination were evaluated. Colorectal cancer patients were divided into two groups as proximal and distal according to tumor localization. Subcutaneous, visceral and retroperitoneal adipose tissue thicknesses of the abdomen were measured using abdominal computed tomography scans.
Results: There was no statistically significant difference between the colorectal cancer group and the control group in terms of body mass index, retroperitoneal and visceral adipose tissue thickness and gender (p=0.091; 0.246; 0.531; 0.190,respectively). The mean age of the colorectal cancer group was higher (p<0.001). The mean subcutaneous adipose tissue thickness of the control group was higher (p=0.045). There was no statistically significant difference between the proximal and distal colorectal cancer group in terms of age, retroperitoneal, subcutaneous and visceral adipose tissue thickness (p=0.734; 0.916; 0.800; 0.170, respectively). The mean body mass index of the group with distal mass was higher (p=0.028). The proportion of males was higher in the group with distal mass than in the group with proximal mass (p=0.024).
Conclusion: In the risky population evaluating the adipose tissue in the abdomen and its distribution before the colorectal cancer is diagnosed or the symptoms develop will indicate which patients should be followed up in more detail and help to prevent more cases of colorectal cancer.

Keywords

computed tomography, colorectal cancer, visceral adipose tissue, abdominal subcutaneous adipose tissue, retroperitoneal adipose tissue

Supporting Institution

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Project Number

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Thanks

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Kolorektal Kanser ve Abdominal Yağ Doku Dağılımı Arasındaki İlişki

Abstract

Amaç: Abdominal subkütan, viseral ve retroperitoneal yağ dokusu kalınlıkları ile obezite arasındaki ilişkiyi incelemek.
Materyal ve Metod: Çalışmaya 62 kontrol ve 68 kolorektal kanser hastası dahil edildi. Hastaların ameliyat öncesi veya kolonoskopik muayenesinden önceki son 6 ay içinde çekilen abdominal bilgisayarlı tomografi tetkikleri değerlendirildi. Kolorektal kanser hastaları tümör lokalizasyonuna göre proksimal ve distal olarak iki gruba ayrıldı. Abdomenin subkütan, viseral ve retroperitoneal yağ doku kalınlıkları abdominal bilgisayarlı tomografi tetkikleri kullanılarak ölçüldü.
Bulgular: Kolorektal kanser grubu ile kontrol grubu arasında vücut kitle indeksi, retroperitoneal ve viseral yağ doku kalınlığı ve cinsiyet açısından istatistiksel olarak anlamlı bir fark yoktu (sırasıyla p = 0.091; 0.246; 0.531; 0.190). Kolorektal kanser grubunun yaş ortalaması daha yüksekti (p <0.001). Kontrol grubunun ortalama subkütan yağ doku kalınlığı daha yüksekti (p = 0.045). Proksimal ve distal kolorektal kanser grubu arasında yaş, retroperitoneal, subkütan ve viseral yağ doku kalınlığı açısından istatistiksel olarak anlamlı bir fark yoktu (sırasıyla p = 0.734; 0.916; 0.800; 0.170). Distal kitle olan grubun ortalama vücut kitle indeksi daha yüksekti (p = 0.028). Distal kitle olan grupta erkeklerin oranı proksimal kitlesi olan gruba göre daha yüksekti (p = 0,024).
Sonuç: Riskli popülasyonda kolorektal kanser teşhisi konmadan veya semptomlar gelişmeden önce abdomendeki yağ dokusunu ve dağılımını değerlendirmek, hangi hastaların daha detaylı izlenmesi gerektiğini gösterecek ve daha fazla kolorektal kanser vakasının oluşumunu önlemeye yardımcı olacaktır.

Keywords

Bilgisayarlı tomografi, kolorektal kanser, viseral yağ dokusu, abdominal subkutan yağ dokusu, retroperitoneal yağ dokusu

Project Number

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