Testicular Tumors: A 15-Year Archive Review and Histopathological Evaluation

Year 2021, , 816 - 821, 20.11.2021

Akgül Arıcı , Elif Akçay , Mümine Görmez Faik Deresoy Fikret Erdemir , Reşit Köseoğlu

https://doi.org/10.16899/jcm.929096

Abstract

Aim: Testicular tumors are one of the most common malignancies in men in the age group of 15-40 years, although they are rarely observed. In our study, it was aimed to evaluate their histopathological features by retrospectively examining of the cases diagnosed as testicular tumor in our department.
Materials and Methods: Age, tumor localization, tumor size, pathological stage, tumor type and frozen information of 65 cases diagnosed as testicular tumor in the Department of Medical Pathology at Tokat Gaziosmanpasa University Faculty of Medicine between 2006-2020 were examined.
Results: The mean age of 65 cases diagnosed as tumor was 37.9±17.73 years. Their ages ranged from 1 to 78 years. Macroscopic tumor diameter was an average of 4.6 ± 2.36 cm, 36 (55.4%) of them were located in the right and 29 (44.6%) of them were located in the left testis. Histopathological diagnosis was germ cell tumor in 53 (81.7%) cases and non-germ cell tumor in 12 (18.3%) cases. The most common tumor was seminoma with 22 (33.9%) cases and the second was mixed germ cell tumor with 19 (29.3%) cases. In components forming mixed germ cell tumors, embryonal carcinoma was the most commonly seen. Intraoperative frozen section examination was performed in 17 cases, it was determined that 10 cases were malignant and 7 cases were benign.
Conclusion: The histopathological and general features of our series of testicular tumor was determined to be compatible with the literature to a great extent. Intraoperative frozen section examination is an important auxiliary diagnostic method in terms of organ preserving surgery.

Keywords

testis, tumor, germ cell, frozen section examination, testis preserving surgery

Testis Tümörleri: 15 Yıllık Arşiv Taraması ve Histopatolojik Değerlendirilmesi

Abstract

Amaç: Testis tümörleri nadir görülmekle birlikte, 15-40 yaş grubundaki erkeklerde en sık görülen malignitelerden biridir. Çalışmamızda bölümümüzde testis tümörü tanısı almış olguların retrospektif olarak incelenip, histopatolojik özelliklerinin değerlendirilmesi amaçlandı.
Gereç ve Yöntem: 2006-2020 yılları arasında Tokat Gaziosmanpaşa Üniversitesi Tıp Fakültesi Tıbbi Patoloji Anabilim Dalı’nda testis tümörü tanısı alan 65 olgunun yaş, tümör lokalizasyonu, tümör boyutu, patolojik evre, tümör tipi ve frozen bilgisi incelendi.
Bulgular: Tümör tanısı alan 65 olgunun yaş ortalaması 37,9±17,73 yıl idi. Yaşları 1-78 yıl arasında değişmekteydi. Makroskopik tümör çapı ortalama 4,6±2,36 cm olup, 36’sı (%55,4) sağ, 29’u (%44,6) sol testis lokalizasyonluydu. Histopatolojik tanı 53 olguda (%81,7) germ hücreli tümör ve 12 olguda (%18,3) germ hücreli dışı tümördü. En sık görülen tümör 22 olgu (%33,9) ile seminom ve ikinci sıklıkta 19 olgu (%29,3) ile mikst germ hücreli tümördü. Mikst germ hücreli tümörleri oluşturan komponentlerde en sık embriyonel karsinom görüldü. İntraoperatif frozen kesit inceleme 17 olguda yapılmış olup, 10 olgunun malign, 7 olgunun benign olduğu saptandı.
Sonuç: Testis tümörü serimizin histopatolojik ve genel özelliklerinin büyük oranda literatür ile uyumlu olduğu saptanmıştır. İntraoperatif frozen inceleme organ koruyucu cerrahi açısından önemli bir yardımcı tanı yöntemidir.

Keywords

testis, tümör, germ hücre, frozen kesit inceleme, testis koruyucu cerrahi

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