Proksimal Özofagusta Heterotopik Gastrik Mukoza Prevalansı ve Klinik ve Endoskopik Bulgular Arasındaki İlişki

Year 2019, Volume: 9 Issue: 4, 338 - 342, 31.12.2019

Hatice Karagöz , Ahmet Karaman

https://doi.org/10.16899/jcm.626167

Abstract

Amaç

Heterotopik gastrik mukoza (HGMPE), genellikle proksimal
özofagusta lokalize olan ektopik gastrik mukoza adasıdır. HGMPE' nin klinik
önemi esas olarak asit üretimi ve neoplastik dönüşüm  kapasitesi ile ilişkilidir. Bu çalışmada
HGMPE prevalansı ile klinik ve endoskopik bulgular arasındaki ilişkiyi
araştırmayı amaçladık.

Yöntem

Aralık 2013 ile Şubat 2018 arasında Acıbadem Kayseri Hastanesi gastroenteroloji ünitesinde özofagogastroduodenoskopi
yapılan 2091 kadın ve 2035 erkek toplam 4126 hasta retrospektif olarak tarandı.
54 kadın ve 68 erkekten oluşan toplam 122 HGMPE + hasta ile yaş ve cinsiyet
açısından eşleştirilmiş 107 kadın ve 134 erkekten oluşan toplam 241 kişilik
HGMPE - kontrol grubu çalışmaya dahil edildi.

Bulgular

Çalışmamızda HGMPE prevalansını % 2.96 olarak saptadık.
Disfaji, hasta grubunda anlamlı olarak yüksek iken, kontrol grubunda abdominal
ağrı daha fazlaydı. HGMPE + ve HGMPE – gruplar arasında reflü özofajit,
duodenal ülser ve alt özofageal sfinkter eksikliği açısından istatistiksel
olarak anlamlı bir fark bulunmadı.

Sonuç

Çalışmalar arasındaki çelişkilere rağmen, eğer endoskopist
bu durumun farkında olursa  HGMPE'nin
daha sık rastlanan bir endoskopik bulgu olabileceğini düşünüyoruz. Bu durumun
klinik önemi ile ilgili tartışmalar devam etse de, artan sayıda neoplastik
transformasyon HGMPE'nin önemini daha da artırmıştır.

Anahtar
kelimeler: Heterotopik gastrik mukoza, Servikal
inlet patch, Özofagus, Laringofaringeal reflü, Disfaji.

Keywords

Heterotopik gastrik mukoza, Servikal inlet patch

The Prevalence of Heterotopic Gastric Mucosa of the Proximal Esophagus and the Relationship Between Clinical and Endoscopic Findings

Abstract

Purpose

In this study, we aimed
to investigate the prevalence of HGMPE and the relationship between clinical
and endoscopic findings.

 Patients
and Methods

Between December 2013 and February
2018, a total of 4126 patients, 2091 women and 2035 men, who underwent
esophagogastroduodenoscopy in the gastroenterology unit of Acıbadem Kayseri Hastanesi were retrospectively screened.

Totally, 122 patients, 54 women and
68 men found to have heterotopic gastric mucosa and a control group of age and
sex matched 241 patients, 107 women and 134 men who do not have heterotopic
gastric mucosa were included the study.

Results

We found the prevalence of HGMPE
2.96 % in our study. Dysphagia was significantly higher in the case group,
whereas abdominal pain was higher in the control group.

Conclusion

Because of the controversies among
the studies we think that HGMPE may be a frequent finding if the endoscopist be
aware of this entity. Although the controversies remain regarding the clinical
significance of this entity, increasing number of cases of neoplastic
transformation has further increased the importance of HGMPE.

Keywords

Heterotopic gastric mucosa, Cervical inlet patch, Esophagus, Laryngopharyngeal reflux, Dysphagia

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