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Kolonoskopide İskemik Kolit Tespit Edilen Hastalar ile Deneyimimiz

Year 2022, Volume: 12 Issue: 1, 38 - 43, 15.01.2022
https://doi.org/10.16899/jcm.931180

Abstract

Giriş ve Amaç: İskemik kolit (İK) özellikle 60 yaş üstündeki hastalarda alt gastrointestinal kanamanın en sık görülen sebeplerinden biridir. Bu çalışmada kolonoskopide İK tespit edilen hastalarının klinik ve demografik özelliklerini araştırdık.

Gereç ve Yöntem: Bu çalışma Ocak 2014-Aralık 2017 tarihleri arasında çeşitli sebeplerle kolonoskopi yapılan hastaların hasta kayıtları incelenerek retrospektif olarak yapılmıştır. Kolonoskopi raporlarında İK ön tanısı olan hastalar çalışmaya alınmıştır. Toplan 130 hasta bulunmuş, 18 hasta veri eksikliği nedeniyle çalışmadan dışlanmış ve çalışma 112 hasta ile yapılmıştır.

Bulgular: Kolonoskopide İK ön tanısı olan 112 hastanın 56’sında kesin İK tanısı konulmuştur (%50). Kesin İK tanısı alan hastaların yaş ortalaması 68 olup hastaların 30’u erkek, 26’sı ise kadın idi. İK hastalarının en sık karın ağrısı, hematokezya, ishal ve ateş şikayeti ile hastaneye başvurduğu görülmüştür. İskemik kolitin en sık sol kolonu tuttuğu görülmüştür. İK tanılı hastaların doppler bulgularında hastaların büyük çoğunluğunda tüm mezenter damarlar ve aort normaldi (%70). İK’e sebep olabilecek predispozan faktörler incelendiğinde hastaların %59’unda hipertansiyon, %59’unda koroner arter hastalığı, %21’inde diyabetes mellitus ve %18’inde kalp yetmezliği izlendi. Hastaların büyük çoğunluğu medikal tedavi ile düzelmiştir (%89). 6 hasta kolon rezeksiyonu için cerrahiye verilmiş (%11), bu hastalardan 4’ü iyileşmiş ancak iki hasta yaygın tromboembolik durum ve buna bağlı geniş iskemi nedeniyle exitus olmuştur (%4).

Sonuç: İK özellikle predispozan risk faktörlerinin olduğu yaşlı erkek hastalarda kanlı ishal ve karın ağrısı ile semptom veren, sıklıkla sol kolonu tutan ve medikal tedaviye iyi yanıt veren bir hastalık olup akut ishal ve karın ağrısı olan her hastada akla gelmelidir.

References

  • 1 Renner P, Kienle K, Dahlke MH, Heiss P, Pfister K, Stroszczynski C, Piso P, Schlitt HJ. Intestinal ischemia: current treatment concepts. Langenbecks Arch Surg 2011; 396 (1): 3-11.
  • 2 Misiakos EP, Tsapralis D, Karatzas T, Lidoriki I, Schizas D, Sfyroeras GS, Moulakakis KG, Konstantos C, Machairas A. Advents in the Diagnosis and Management of Ischemic Colitis. Front Surg 2017; 4: 47.
  • 3 Fitzgerald JF, Hernandez LO, III. Ischemic colitis. Clin Colon Rectal Surg 2015: 28: 93–8.
  • 4 Yngvadottir Y, Karlsdottir BR, Hreinsson JP, Ragnarsson G, Mitev RUM, Jonasson JG, et al. The incidence and outcome of ischemic colitis in a population-based setting. Scand J Gastroenterol 2017; 52: 704–10.
  • 5 Cruz C, Abujudeh HH, Nazarian RM, Thrall JH. Ischemic colitis: spectrum of CT findings, sites of involvement and severity. Emerg Radiol 2015; 22: 357–65.
  • 6 Longstreth GF, Yao JF. Epidemiology, clinical features, high risk factors, and outcome of acute large bowel ischemia. Clin Gastroenterol Hepatol 2009; 7: 1075–80.
  • 7 Noh M, Yang SS, Jung SW, Park JH, Im YC, Kim KY. Poor prognostic factors in patients who underwent surgery for acute non-occlusive ischemic colitis. World J Emerg Surg 2015; 10: 12.
  • 8 Mohanapriya T, Balaji Singh K, Arulappan T, Shobhana R. Ischemic colitis. Indian J Surg 2012; 74: 396–400.
  • 9 Washington C, Carmichael JC. Management of ischemic colitis. Clin Colon Rectal Surg 2012; 25: 228–35.
  • 10 Moninska P, Fichna J. Ischemic colitis: current diagnosis and treatment. Curr Drug Targets 2015; 16: 209-18.
  • 11 Lyu G, Li J, Liu AL, Zhao YX, Yang H, Qian JM. Zhonghua Nei Ke Za Zhi 2016; 55(6): 466-9.
  • 12 Chen M, Remer EM, Liu X, Lopez R, Shen B. Identification of the distinguishing features of Crohn's disease and ischemic colitis using computed tomographic enterography. Gastroenterol Rep (Oxf) 2017; 5(3): 219-25.
  • 13 Choi SR, Jee SR, Song GA, et al. Predictive Factors for Severe Outcomes in Ischemic Colitis. Gut Liver 2015; 9(6): 761-6.
  • 14 Medina C, Vilaseca J, Videla S, Fabra R, Armengol-Miro JR, Malagelada JR. Outcome of patients with ischemic colitis: review of fifty-three cases. Dis Colon Rectum 2004; 47(2): 180-4.
  • 15 Hreinsson J P, Gumundsson S, Kalaitzakis E, Björnsson E S. Lower gastrointestinal bleeding: incidence, etiology, and outcomes in a population-based setting. Eur J Gastroenterol Hepatol 2013; 25(1): 37–43.
  • 16 Park C J, Jang M K, Shin W G. et al.Can we predict the development of ischemic colitis among patients with lower abdominal pain? Dis Colon Rectum 2007; 50(2): 232–8.
  • 17 Sun D, Wang C, Yang L, Liu M, Chen F. The predictors of the severity of ischaemic colitis: a systematic review of 2823 patients from 22 studies. Colorectal Dis 2016; 18(10): 949-58.
  • 18 Jessurun J. The Differential Diagnosis of Acute Colitis: Clues to a Specific Diagnosis. Surg Pathol Clin 2017; 10(4): 863-85.
  • 19 Cerilli LA, Greenson JK. The differential diagnosis of colitis in endoscopic biopsy specimens: a review article. Arch Pathol Lab Med 2012; 136(8): 854-64.
  • 20 Brandt LJ, Feuerstadt P, Blaszka MC. Anatomic patterns, patient characteristics, and clinical outcomes in ischemic colitis: a study of 313 cases supported by histology. Am J Gastroenterol 2010; 105(10): 2245-53.
  • 21 Beck DE, de Aguilar-Nascimento JE. Surgical management and outcome in acute ischemic colitis. Ochsner J 2011; 11(3): 282-5.
  • 22 Rania H, Mériam S, Rym E, et al. Ischemic colitis in five points: an update 2013. Tunis Med 2014; 92(5): 299-303.
  • 23 Gilshtein H, Hallon K, Kluger Y. Ischemic colitis caused increased early and delayed mortality. World J Emerg Surg 2018; 13: 31.

Our Experience with Patients That Diagnosed Ischemic Colitis in Colonoscopy

Year 2022, Volume: 12 Issue: 1, 38 - 43, 15.01.2022
https://doi.org/10.16899/jcm.931180

Abstract

Aim: Ischemic colitis (IC) is one of the most common causes of lower gastrointestinal bleeding, especially in patients over 60 years of age. In this study, we investigated the clinical and demographic characteristics of patients with IC detected by colonoscopy.

Material and Method: This study was conducted retrospectively by examining the patient records of patients who underwent colonoscopy for various reasons between January 2014 and December 2017. Patients with IC pre-diagnosis in the colonoscopy reports were included in the study. A total of 130 patients were found, 18 patients were excluded from the study due to lack of data and the study was conducted with 112 patients.

Results: Definitive IC was diagnosed in 56 of 112 patients who had a preliminary diagnosis of colonoscopy (50%). The average age of patients diagnosed with definitive IC was 68, of which 30 were male and 26 were female. It was observed that IC patients applied to the hospital with complaints of abdominal pain, hematochezia, diarrhea and fever. It is observed that ischemic colitis is most frequently affects left colon. In the doppler findings of patients with IC, all mesenteric vessels and aorta were normal in the vast majority of patients (70%). When predisposing factors that may cause IC were examined, hypertension was observed in 59% of patients, coronary artery disease in 59%, diabetes mellitus in 21% and heart failure in 18%. The vast majority of patients improved with medical therapy (89%). Six patients were given surgery for colon resection (11%), 4 of these patients recovered, but two patients became exitus due to the common thromboembolic condition and associated extensive ischemia (4%).

Conclusion: IC is a disease that presents symptoms such as bloody diarrhea and abdominal pain, especially in elderly male patients with predisposing risk factors, frequently seen in the left colon and responds well to medical treatment, and should be considered in every patient with acute diarrhea and abdominal pain.

References

  • 1 Renner P, Kienle K, Dahlke MH, Heiss P, Pfister K, Stroszczynski C, Piso P, Schlitt HJ. Intestinal ischemia: current treatment concepts. Langenbecks Arch Surg 2011; 396 (1): 3-11.
  • 2 Misiakos EP, Tsapralis D, Karatzas T, Lidoriki I, Schizas D, Sfyroeras GS, Moulakakis KG, Konstantos C, Machairas A. Advents in the Diagnosis and Management of Ischemic Colitis. Front Surg 2017; 4: 47.
  • 3 Fitzgerald JF, Hernandez LO, III. Ischemic colitis. Clin Colon Rectal Surg 2015: 28: 93–8.
  • 4 Yngvadottir Y, Karlsdottir BR, Hreinsson JP, Ragnarsson G, Mitev RUM, Jonasson JG, et al. The incidence and outcome of ischemic colitis in a population-based setting. Scand J Gastroenterol 2017; 52: 704–10.
  • 5 Cruz C, Abujudeh HH, Nazarian RM, Thrall JH. Ischemic colitis: spectrum of CT findings, sites of involvement and severity. Emerg Radiol 2015; 22: 357–65.
  • 6 Longstreth GF, Yao JF. Epidemiology, clinical features, high risk factors, and outcome of acute large bowel ischemia. Clin Gastroenterol Hepatol 2009; 7: 1075–80.
  • 7 Noh M, Yang SS, Jung SW, Park JH, Im YC, Kim KY. Poor prognostic factors in patients who underwent surgery for acute non-occlusive ischemic colitis. World J Emerg Surg 2015; 10: 12.
  • 8 Mohanapriya T, Balaji Singh K, Arulappan T, Shobhana R. Ischemic colitis. Indian J Surg 2012; 74: 396–400.
  • 9 Washington C, Carmichael JC. Management of ischemic colitis. Clin Colon Rectal Surg 2012; 25: 228–35.
  • 10 Moninska P, Fichna J. Ischemic colitis: current diagnosis and treatment. Curr Drug Targets 2015; 16: 209-18.
  • 11 Lyu G, Li J, Liu AL, Zhao YX, Yang H, Qian JM. Zhonghua Nei Ke Za Zhi 2016; 55(6): 466-9.
  • 12 Chen M, Remer EM, Liu X, Lopez R, Shen B. Identification of the distinguishing features of Crohn's disease and ischemic colitis using computed tomographic enterography. Gastroenterol Rep (Oxf) 2017; 5(3): 219-25.
  • 13 Choi SR, Jee SR, Song GA, et al. Predictive Factors for Severe Outcomes in Ischemic Colitis. Gut Liver 2015; 9(6): 761-6.
  • 14 Medina C, Vilaseca J, Videla S, Fabra R, Armengol-Miro JR, Malagelada JR. Outcome of patients with ischemic colitis: review of fifty-three cases. Dis Colon Rectum 2004; 47(2): 180-4.
  • 15 Hreinsson J P, Gumundsson S, Kalaitzakis E, Björnsson E S. Lower gastrointestinal bleeding: incidence, etiology, and outcomes in a population-based setting. Eur J Gastroenterol Hepatol 2013; 25(1): 37–43.
  • 16 Park C J, Jang M K, Shin W G. et al.Can we predict the development of ischemic colitis among patients with lower abdominal pain? Dis Colon Rectum 2007; 50(2): 232–8.
  • 17 Sun D, Wang C, Yang L, Liu M, Chen F. The predictors of the severity of ischaemic colitis: a systematic review of 2823 patients from 22 studies. Colorectal Dis 2016; 18(10): 949-58.
  • 18 Jessurun J. The Differential Diagnosis of Acute Colitis: Clues to a Specific Diagnosis. Surg Pathol Clin 2017; 10(4): 863-85.
  • 19 Cerilli LA, Greenson JK. The differential diagnosis of colitis in endoscopic biopsy specimens: a review article. Arch Pathol Lab Med 2012; 136(8): 854-64.
  • 20 Brandt LJ, Feuerstadt P, Blaszka MC. Anatomic patterns, patient characteristics, and clinical outcomes in ischemic colitis: a study of 313 cases supported by histology. Am J Gastroenterol 2010; 105(10): 2245-53.
  • 21 Beck DE, de Aguilar-Nascimento JE. Surgical management and outcome in acute ischemic colitis. Ochsner J 2011; 11(3): 282-5.
  • 22 Rania H, Mériam S, Rym E, et al. Ischemic colitis in five points: an update 2013. Tunis Med 2014; 92(5): 299-303.
  • 23 Gilshtein H, Hallon K, Kluger Y. Ischemic colitis caused increased early and delayed mortality. World J Emerg Surg 2018; 13: 31.
There are 23 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Original Research
Authors

Volkan Gökbulut 0000-0002-7906-2479

Mustafa Kaplan 0000-0002-6959-675X

Selcuk Dısıbeyaz 0000-0002-1637-7684

Sabite Kacar 0000-0002-3257-3546

Hale Sümer This is me 0000-0001-5663-0683

Püren Gökbulut 0000-0002-6287-7655

İlyas Tenlik 0000-0001-9546-2918

Adem Aksoy 0000-0003-3823-3654

Publication Date January 15, 2022
Acceptance Date October 9, 2021
Published in Issue Year 2022 Volume: 12 Issue: 1

Cite

AMA Gökbulut V, Kaplan M, Dısıbeyaz S, Kacar S, Sümer H, Gökbulut P, Tenlik İ, Aksoy A. Our Experience with Patients That Diagnosed Ischemic Colitis in Colonoscopy. J Contemp Med. January 2022;12(1):38-43. doi:10.16899/jcm.931180