Pandemi Hastanesine Başvuran Hastaların Bilgisayarlı Tomografi ve PCR Sonuçlarının COVID-19 Açısından Değerlendirilmesi

Year 2022, Volume: 12 Issue: 3, 465 - 470, 30.05.2022

Gülay Maçin Salih Maçin Prof. Dr. Uğur Arslan

https://doi.org/10.16899/jcm.1066691

Abstract

Amaç: COVID-19, öncelikle solunum sistemini etkileyen ve hızla yayılan bulaşıcı bir hastalıktır. COVID-19 pandemisininde Bilgisayarlı Tomografi (BT) ve ters transkripsiyon-polimeraz zincir reaksiyonu (RT-PCR) gibi tanı yöntemleri önem kazanmıştır. Bu çalışmanın amacı, RT-PCR yöntemi ile COVID-19 tanısı konulan hastaların Toraks BT ile anormal parankimal bulguların görünüm ve dağılımını değerlendirmektir. Bu hastalarda akciğer enfeksiyonun şiddeti ile hastalığın klinik seyri arasındaki ilişkiyi değerlendirmektir.
Gereç ve Yöntem: Aralık 2020 ile Şubat 2021 tarihleri arasında Konya Beyhekim Eğitim ve Araştırma Hastanesi'ne COVID-19 ön tanısı ile başvuran hastalar (n:613) retrospektif olarak değerlendirildi. Nazofaringeal sürüntü örnekleri Selçuk Üniversitesi Tıp Fakültesi Mikrobiyoloji Laboratuvarında RT-PCR ile COVID-19 açısından çalışıldı. COVID-19 PCR testi pozitif olan 361 hastanın toraks BT görüntüleri COVID-19 pnömonisi açısından incelendi. Covid-19 pnomonisi olan hastaların klinik seyirleri değerlendirildi.
Bulgular: 613 hastanın 361'inde (%58) RT-PCR testi pozitifti. RT-PCR testi pozitif olan hastaların 243'ünde (%64,8) pnömoni bulguları varken, 118'inde akciğer parankimi normaldi. Covid-19 hastalarının akciğer bulgularının büyük bir kısmını (%90) buzlu cam görüntüsü oluşturuyordu. Hastaların %22'sinde konsolidasyon, %20'sinde buzlu cam ile konsolidasyon birlikteliği vardı. 34 hastada (%13,9) çılgın döşeme paterni ve 19 (%7,8) hastada ters halo görünümü vardı. Akciğer enfeksiyonu tutulumunun şiddeti ile hastalığın klinik seyri arasında anlamlı ilişki bulundu.
Sonuç: Etkin hasta yönetimi ve tedavisi için tanısal görüntüleme özelliklerinin kapsamlı bir şekilde anlaşılması şarttır.

Keywords

COVID-19, Bilgisayarlı tomografi, PCR

Evaluation of Computed Tomography and PCR Results of Patients Admitted to Pandemic Hospital in Terms of COVID-19

Abstract

Aim: COVID-19 is an infectious disease that primarily affects the respiratory system and spreads rapidly. Diagnostic methods as computed Tomography (CT) and reverse transcription-polymerase chain reaction (RT-PCR) have gained importance in the COVID-19 pandemic. The aim of this study is to evaluate the appearance and distribution of abnormal parenchymal findings with Thorax CT in patients diagnosed with COVID-19 by RT-PCR method. And to evaluate the relationship between the severity of lung infection and the clinical course of the disease in these patients.

Materials and Methods: Patients (n:613) with a preliminary diagnosis of COVID-19 who applied to Konya Beyhekim Training and Research Hospital were evaluated retrospectively between December 2020 and February 2021. Nasopharyngeal samples were studied for COVID-19 with RT-PCR by Selcuk University Medical Faculty Microbiology Laboratory. Thoracic CT images of 361 patients with positive COVID-19 PCR tests were examined for the presence of COVID-19 pneumonia. The clinical course of patients with Covid-19 pneumonia was evaluated.

Results: RT-PCR results was positive in 361 (58%) of 613 patients. While 243 (64.8%) of the PCR positive patients had signs of pneumonia, 118 of them had normal lung parenchyma (GGO). There was consolidation in 22% of the patients, and ground glass with consolidation in 20%. 34 patients (13.9%) had crazy-paving pattern and 19 (7.8%) patients had reverse halo appearance. A significant relationship was found between the severity of lung infection involvement and the clinical course of the disease.

Conclusion: A comprehensive understanding of diagnostic imaging features is essential for effective patient management and treatment.

Keywords

COVID-19, Computed Tomography, PCR

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