COVID-19 Pnömonisi Sonrası AntiHBs Değerlerindeki Değişiklikler

Year 2022, Volume: 12 Issue: 4, 537 - 542, 31.07.2022

Perihan Özkan Gümüşkaya Özgür Altun Nur Karakütük Yüztaş Neslihan Özsoy Gülten Aydın Tutak Emine Yıldırım Mine Adaş Mehmet Küçük

https://doi.org/10.16899/jcm.1062780

Abstract

Amaç: Coronavirus-19 hastalığı (COVID-19) sırasında antiHBS titresinin koruyucu değerin altına düşüp düşmediğini belirlemeyi amaçladık.
Gereç ve Yöntem: Son 1 yıl içinde pozitif antiHbs değerleri kontrol edilen 67 hasta ile prospektif bir çalışma yapıldı. Demografik veriler ve önceki antiHBs değerleri hasta dosyalarından toplandı ve COVID-19 enfeksiyonundan bir ay sonra kontrol edilen yeni antiHBs titrelerinin laboratuvar bulguları öncekilerle karşılaştırıldı.
Bulgular: COVID-19 sonrası yapılan değerlendirmede COVID-19 hastalarının antiHBs düzeylerinde COVID-19 enfeksiyonu öncesi önceki değerlere göre istatistiksel olarak anlamlı düşüş saptandı(p<0,001).
Sonuç: Çalışmamızda COVID-19 enfeksiyonu sonrası AntiHBs düzeylerinde istatistiksel olarak anlamlı bir düşüş olduğunu ancak bunun koruyucu antiHBs düzeyinin altında olmadığını gördük. Sonuç olarak COVID-19 enfeksiyonu sırasında veya sonrasında hepatit B'ye karşı güçlendirici aşıya gerek olmadığını söyleyebiliriz ancak hasta sayısı daha yüksek olan çalışmalarla desteklenmesi uygun olur.

Keywords

COVID-19, antiHBs değerleri, değişen titreler.

Supporting Institution

yok

Project Number

reg: E- 48670771- 514.10

The Changes In The AntiHBs Values Following COVID-19 Pneumonia

Abstract

Background/aim: We aimed to determine if there is a decrease in antiHBS titer below the protective value during Coronavirus-19 disease (COVID-19).
Materials and methods: A prospective study was made of 67 patients who had positive antiHbs values checked in the last 1 year. Demographic data and the previous antiHBs values were collected from the patient files and the laboratory findings of new antiHBs titers checked after one months later following COVID-19 infection were compared with the previous ones.
Results: In the postcovid evaluation, a statistically significant decrease in the antiHBs levels of COVID-19 patients was determined with respect to previous values before COVID-19 infection (p<0,001).
Conclusion: In our study, we found that there was a statistically significant decrease in AntiHBs levels after COVID-19 infection, but none of them were below protective antiHBs levels. As a result, we can say a booster vaccination against hepatitis B is not needed during or after COVID-19 infection, but it would be appropriate to support it with studies with a higher number of patients.

Keywords

COVID-19, antiHBs values, changing titers.

Project Number

reg: E- 48670771- 514.10

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