Case Report
BibTex RIS Cite

Ocular Tuberculosis Presenting with Granulomatous Uveitis in an Adolescent Patient: A Rare Case Report

Year 2022, Volume: 12 Issue: 5, 820 - 822, 30.09.2022
https://doi.org/10.16899/jcm.1107476

Abstract

Tuberculosis continues to be a significant global public health issue. Tuberculosis most often affects the lungs. However, children are more likely to have extrapulmonary involvement compared to adults. Ocular involvement is a rare extrapulmonary manifestation of tuberculosis. Ocular tuberculosis may affect any part of the eye and can be remain unnoticed due to the lack of clinically evident symptoms or findings, if there is no history of tuberculosis contact or other systemic signs or if these are not questioned. Here, we present an adolescent case who was diagnosed with pulmonary and ocular tuberculosis when investigating the underlying cause of granulomatous uveitis and successfully controlled with four drug regimen anti-tuberculosis and methylprednisolone treatment. In conclusion, ocular tuberculosis is an important cause of ocular morbidity. Diagnosis and follow-up require a multidisciplinary approach.

References

  • Berti E, Galli L, Venturini E, Martini M, Chiappini E. Tuberculosis in childhood: a systematic review of national and international guidelines. BMC Infect Dis. 2014;14(Suppl 1):S3.
  • Cruz AT, Starke JR: TuberculosisIn: Cherry JD, Kaplan SL, Steinbach WJ, Hotez PJ, eds. Feigin and Cherry's textbook of pediatric infectious diseases, 8th ed. Philadelphia, PA: Elsevier. 2018;958-88.
  • Özgür Gündeşlioğlu Ö, Kocabaş E. Extrapulmonary tuberculosis in childhood. Turkiye Klinikleri J Pediatr Sci 2016;12(3)32-8.
  • Vasconcelos-Santos DV, Rao PK, Davie JB, et al. Clinical features of tuberculous serpiginouslike choroiditis in contrast to classic serpiginous choroiditis. Arch Ophthalmol 2010;128(7):853–58.
  • Ebu El-Asrar AM, Abouammoh M, Al-Mezaine HS. Tuberculous uveitis. Int Ophthalmol Clin 2010;50(2):19–39.
  • Albert DM, Raven ML. Ocular tuberculosis. Microbiol Spectr 2016;4(6):1–36.
  • Snow KJ, Cruz AT, Seddon JA et al. Adolescent tuberculosis. Lancet Child Adolesc Health 2020;4(1):68–79.
  • Seddon JA, Chiang SS, Esmail H, Coussens AK. The wonder years: what can primary school children teach us about immunity to Mycobacterium tuberculosis? Front Immunol 2018; 9:2946.
  • Donahue HC. Ophthalmologic experience in a tuberculosis sanatorium. Am J Ophthalmol 1967;64(4):742-8.
  • Elangovan S, Govindarajan S, Mayilvakanam L, Gunasekaran N. Clinical profile and treatment response of patients with ocular inflammation due to presumed ocular tuberculosis: a retrospective study. Turk J Ophthalmol 2019; 49(4): 188–93.
  • Yang P, Qi J. Ocular tuberculosis should not be neglected. Zhonghua Yan Ke Za Zhi 2015;51(10):726-9.
  • Al-Shakarchi F. Mode of presentations and management of presumed tuberculous uveitis at a referral center. Iraqi Postgrad Med J 2015;14(1):91-5.

Adolesan Bir Hastada Granülomatöz Üveit ile Seyreden Oküler Tüberküloz: Nadir Bir Olgu Sunumu

Year 2022, Volume: 12 Issue: 5, 820 - 822, 30.09.2022
https://doi.org/10.16899/jcm.1107476

Abstract

Tüberküloz tüm dünyada önemli bir halk sağlığı sorunu olarak devam etmektedir. Tüberküloz en sık akciğerleri tutar. Ancak çocuklarda erişkinlere göre ekstrapulmoner tutulum daha yaygındır. Ekstrapulmoner tutulum içinde göz tutulumu oldukça nadirdir. Oküler tüberküloz uveal traktın tamamının inflamasyonuna yol açabilir. Oluşturduğu granülomatöz üveit hastalığa özgü olmadığı için tüberküloz temas öyküsü ya da diğer sistemik belirtiler yoksa, ya da sorgulanmazsa pratikte gözden kaçabilmektedir. Bu yazıda granülomatöz üveit nedeni araştırılır iken pulmoner ve oküler tüberküloz tanısı konularak dörtlü anti tüberküloz ve metilprednizolon tedavisi ile hastalığı kontrol altına alınan adelösan bir olguyu sunacağız. Sonuç olarak, oküler tüberküloz önemli bir oküler morbidite nedenidir. Tanı ve takibi multidisipliner bir yaklaşım gerektirir.

References

  • Berti E, Galli L, Venturini E, Martini M, Chiappini E. Tuberculosis in childhood: a systematic review of national and international guidelines. BMC Infect Dis. 2014;14(Suppl 1):S3.
  • Cruz AT, Starke JR: TuberculosisIn: Cherry JD, Kaplan SL, Steinbach WJ, Hotez PJ, eds. Feigin and Cherry's textbook of pediatric infectious diseases, 8th ed. Philadelphia, PA: Elsevier. 2018;958-88.
  • Özgür Gündeşlioğlu Ö, Kocabaş E. Extrapulmonary tuberculosis in childhood. Turkiye Klinikleri J Pediatr Sci 2016;12(3)32-8.
  • Vasconcelos-Santos DV, Rao PK, Davie JB, et al. Clinical features of tuberculous serpiginouslike choroiditis in contrast to classic serpiginous choroiditis. Arch Ophthalmol 2010;128(7):853–58.
  • Ebu El-Asrar AM, Abouammoh M, Al-Mezaine HS. Tuberculous uveitis. Int Ophthalmol Clin 2010;50(2):19–39.
  • Albert DM, Raven ML. Ocular tuberculosis. Microbiol Spectr 2016;4(6):1–36.
  • Snow KJ, Cruz AT, Seddon JA et al. Adolescent tuberculosis. Lancet Child Adolesc Health 2020;4(1):68–79.
  • Seddon JA, Chiang SS, Esmail H, Coussens AK. The wonder years: what can primary school children teach us about immunity to Mycobacterium tuberculosis? Front Immunol 2018; 9:2946.
  • Donahue HC. Ophthalmologic experience in a tuberculosis sanatorium. Am J Ophthalmol 1967;64(4):742-8.
  • Elangovan S, Govindarajan S, Mayilvakanam L, Gunasekaran N. Clinical profile and treatment response of patients with ocular inflammation due to presumed ocular tuberculosis: a retrospective study. Turk J Ophthalmol 2019; 49(4): 188–93.
  • Yang P, Qi J. Ocular tuberculosis should not be neglected. Zhonghua Yan Ke Za Zhi 2015;51(10):726-9.
  • Al-Shakarchi F. Mode of presentations and management of presumed tuberculous uveitis at a referral center. Iraqi Postgrad Med J 2015;14(1):91-5.
There are 12 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Report
Authors

Nisa Nur Tapaç 0000-0002-7464-2394

Ümmühan Çay 0000-0001-5803-878X

Fatma Kılınç 0000-0001-7059-245X

Selime Teleke Kaymaz This is me 0000-0001-8572-6828

Özlem Özgür Gündeşlioğlu 0000-0003-2202-7645

Derya Alabaz 0000-0003-4809-2883

Selçuk Sızmaz 0000-0003-3138-1507

Early Pub Date July 11, 2022
Publication Date September 30, 2022
Acceptance Date May 31, 2022
Published in Issue Year 2022 Volume: 12 Issue: 5

Cite

AMA Tapaç NN, Çay Ü, Kılınç F, Kaymaz ST, Özgür Gündeşlioğlu Ö, Alabaz D, Sızmaz S. Ocular Tuberculosis Presenting with Granulomatous Uveitis in an Adolescent Patient: A Rare Case Report. J Contemp Med. September 2022;12(5):820-822. doi:10.16899/jcm.1107476