A Comprehensive Review of Paternal Causes of Recurrent Pregnancy Loss

Year 2025, Volume: 15 Issue: 4, 197 - 202, 31.07.2025

Damica Clerveau Sathees Chandra

https://doi.org/10.16899/jcm.1658279

Abstract

Abstract:

Approximately 5% of couples attempting to reproduce face the challenge of recurrent pregnancy loss. Sadly, more than 50% of those couples will have their case remain unexplained. This can be problematic when families are trying to conceive. Past research mainly focused on maternal causes of recurrent pregnancy loss. A shift in research towards investigating paternal etiologies has revealed more causes of recurrent pregnancy loss. New research has shown how paternal age, physical health, lifestyle habits, sperm characteristics, metabolic disorders, inflammatory disorders, and clotting disorders all influence pregnancy outcomes. The purpose of this paper is to provide a review of the past twenty years of literature investigating the underexplored paternal causes of recurrent pregnancy loss.

Keywords

Pregnancy Outcome , Male Fertility , Reproductive Medicine , Spermatozoa , Pregnancy Complication

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