THE SYNCHRONIZATION BEHAVIOR OF BASAL GANGLIA

Year 2019, Volume: 4 Issue: 2, 38 - 45, 31.12.2019

Yüksel Çakir

Abstract

A
network model of basal ganglia (BG) that comprises striatum, internal and
external segments of globus pallidus, subthalamic nucleus, substantia nigra
pars reticulate neuronal sub populations and thalamus is constructed. The
dynamic behavior of network is investigated using Izhikevich neuron model. The
influences of dopamine, the synaptic strength and the neuronal interconnection
density on the synchronization behavior of the subpopulations are investigated.
In the case of dopamine depletion, the increased striatal synchronization is
observed. Considerable effect on the synchronization of other basal ganglia sub
populations is not observed in the case of dopamine depletion. The highest
synchronization values are observed for the lowest synaptic strength and the neuronal
interconnection density. The decreased neuronal interconnection density causes
a decrease in the fluctuation in synchronization in thalamic neurons depending
on dopamine value.

Keywords

basal ganglia, synchronization

Supporting Institution

TUBITAK BIDEB

Project Number

2219

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