Epileptik Bir Çocukta Amanita Virosa Alımı Sonrası Refrakter Status Epileptikus Oluşması

Abstract

Giriş: Status epileptikus nöbetinin benzodiyazepin uygulanmasından sonra bir geleneksel entiepileptik ilaç infüzyonuna rağmen devam etmesi ise refrakter status epileptikus olarak tanımlanmaktadır. Mantar zehirlenmeleri değişik klinik tablolara neden olabilmektedir. Mantar zehirlenmelerine bağlı epileptik nöbet geliştiği bilinmekle birlikte literatürde amanita virosa grubu mantar zehirlenmesine bağlı status epileptikus geliştiğine dair bir bilgi bulunmamaktadır. Olgu Sunumu: Altı yaşında, son iki yıldır nöbet öyküsü olmayan ve ilaçlarını düzenli kullanan epileptik erkek hasta, mantar alımı sonrası refrakter status epileptikus tablosunda acil servise getirildi. Antiepileptik tedavi ile kontrol altına alınamayan nöbet aktivitesi genel anestezi eşliğinde entübasyon ve mekanik ventilasyon uygulaması ile kontrol altına alındı. Laboratuar incelemeleri, PTZ ve aPTT yüksekliği dışında normaldi. Takibinde ek problem olmayan ve stabil hale gelen hasta yatışının beşinci günde şifa ile taburcu edildi. Sonuç: Hastada mantar zehirlenmesinin konvülziyon eşiğini düşürücü etkisinin olabileceği düşünüldü. Bu olgu ile zehirlenmelerde kliniğin her zaman klasik literatür bilgilerine uymayabileceği, bazen de farklı kliniklerin bir hastada aynı anda görülebileceğinin düşünülmesi gerektiği vurgulandı.

Keywords

• Amanita virosa, çocuk, mantar zehirlenmesi, refrakter, status epileptikus

Refractory Status Epilepticus After Ingestion of Amanita Virosa in an Epileptic Child

Abstract

Introduction: Status epilepticus is considered refractory when seizure activity continues after receiving treatment with a benzodiazepine followed by infusion of traditional antiepileptic drugs. Mushroom poisoning may lead to variable clinical pictures. Although it is known that mushroom poisoning may develop epileptic seizures, there are no data about status epilepticus associated with amanita virosa mushroom poisoning in the literature. Case Report: A 6-year-old epileptic patient who regularly used antiepileptic drugs and had no seizures for 2 years was admitted to the emergency department due to refractory status epilepticus after ingestion of mushroom. Seizures that were refractory to antiepileptic therapy was controlled with intubation and mechanical ventilation after general anesthesia. Laboratory tests were normal, except elevated PTZ and aPTT. The patient, who had no additional problems and stabilized, was discharged on the fifth day of admission. Conclusion: We suggested that mushroom poisoning may reduce the threshold for seizures in our patient. In this study, it is emphasized that different clinical features may be found in a patient at the same time

Keywords

• Amanita virosa, child, mushroom poisoning, refractory, status epilepticus

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