Research Article

PREDICTING THE LOCATION OF THE UTERINE CERVICAL OS FROM 2D IMAGES WITH CNN

Volume: 8 Number: 5 December 29, 2020
TR EN

PREDICTING THE LOCATION OF THE UTERINE CERVICAL OS FROM 2D IMAGES WITH CNN

Abstract

In an automated cervical cancer test, the prediction of the location of the cervical os from 2D images is required. Cervical os is the reference point to determine the lesion's location by either using cervical four-quadrant location or by 12 o’clock locations. Precise detection of the cervical os point ensures correct addressing of the lesions. This study used a 6-layer convolutional neural network to predict the center of the cervical os’ coordinates (x,y) on 2D grayscale images. We used a holistic approach without masking any visual element to predict the location of the cervical os. The 2D images were obtained using a telecentric lens and a CCD camera with light wavelengths of 500 550 nanometers. Because of the limited number of image samples (145 images), we used augmentation techniques to increase the training set size by rotating each original image in 1-degree increments from -30 degrees to +30 degrees relative to the center of the image. The 6-layer convolutional neural network was tested on 21 unseen cervix images using augmentation data. The outcomes showed that the image center-based augmentation technique improves the prediction performance. We obtained 2.4 RMSE in predicting the location of the cervical os.

Keywords

Supporting Institution

Scientific and Technological Research Council of Turkey

Project Number

116S349

Thanks

This study was supported by the Scientific and Technological Research Council of Turkey (TÜBİTAK) with Grant No: 116S349.

References

  1. Das, A., Kar, A., Bhattacharyya, D., 2011. Elimination of specular reflection and identification of ROI: The first step in automated detection of Cervical Cancer using Digital Colposcopy. In: 2011 IEEE International Conference on Imaging Systems and Techniques. pp. 237–241.
  2. Greenspan, H., Gordon, S., Zimmerman, G., Lotenberg, S., Jeronimo, J., Antani, S., Long, R., 2009. Automatic Detection of Anatomical Landmarks in Uterine Cervix Images. IEEE Transactions on Medical Imaging. 28, 454–468.
  3. Guo, P., Xue, Z., Long, L.R., Antani, S.K., 2020. Anatomical landmark segmentation in uterine cervix images using deep learning. In: Chen, P.-H., Deserno, T.M. (Eds.), Medical Imaging 2020: Imaging Informatics for Healthcare, Research, and Applications. SPIE, pp. 258–267.
  4. Kudva, V., Prasad, K., Guruvare, S., 2017. Detection of Specular Reflection and Segmentation of Cervix Region in Uterine Cervix Images for Cervical Cancer Screening. IRBM. 38, 281–291.
  5. Lange, H., 2005. Automatic glare removal in reflectance imagery of the uterine cervix. In: Fitzpatrick, J.M., Reinhardt, J.M. (Eds.), Medical Imaging 2005: Image Processing, Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series. pp. 2183–2192.
  6. Liu, J., Li, L., Wang, L., 2018. Acetowhite region segmentation in uterine cervix images using a registered ratio image. Computers in Biology and Medicine. 93, 47–55.
  7. Patil, D.B., Gaikwad, M.S., Singh, D.K., Vishwanath, T.S., 2016. Semi-automated lession grading in cervix images with Specular Reflection removal. In: 2016 International Conference on Inventive Computation Technologies (ICICT). pp. 1–5.
  8. Xue, Z., Antani, S., Long, L.R., M.D., J.J., Thoma, G.R., 2007. Comparative performance analysis of cervix ROI extraction and specular reflection removal algorithms for uterine cervix image analysis. In: Pluim, J.P.W., Reinhardt, J.M. (Eds.), Medical Imaging 2007: Image Processing. SPIE, pp. 1507–1515.

Details

Primary Language

English

Subjects

Computer Software

Journal Section

Research Article

Publication Date

December 29, 2020

Submission Date

November 20, 2020

Acceptance Date

December 19, 2020

Published in Issue

Year 2020 Volume: 8 Number: 5

APA
Danışman, T., Üncü, Y. A., Karaçaylı, D., Bilge, U., Birge, Ö., Bakır, M., Göksu, M., Şimşek, T., & Canpolat, M. (2020). PREDICTING THE LOCATION OF THE UTERINE CERVICAL OS FROM 2D IMAGES WITH CNN. Mühendislik Bilimleri Ve Tasarım Dergisi, 8(5), 52-57. https://doi.org/10.21923/jesd.828457
AMA
1.Danışman T, Üncü YA, Karaçaylı D, et al. PREDICTING THE LOCATION OF THE UTERINE CERVICAL OS FROM 2D IMAGES WITH CNN. JESD. 2020;8(5):52-57. doi:10.21923/jesd.828457
Chicago
Danışman, Taner, Yiğit Ali Üncü, Deniz Karaçaylı, et al. 2020. “PREDICTING THE LOCATION OF THE UTERINE CERVICAL OS FROM 2D IMAGES WITH CNN”. Mühendislik Bilimleri Ve Tasarım Dergisi 8 (5): 52-57. https://doi.org/10.21923/jesd.828457.
EndNote
Danışman T, Üncü YA, Karaçaylı D, Bilge U, Birge Ö, Bakır M, Göksu M, Şimşek T, Canpolat M (December 1, 2020) PREDICTING THE LOCATION OF THE UTERINE CERVICAL OS FROM 2D IMAGES WITH CNN. Mühendislik Bilimleri ve Tasarım Dergisi 8 5 52–57.
IEEE
[1]T. Danışman et al., “PREDICTING THE LOCATION OF THE UTERINE CERVICAL OS FROM 2D IMAGES WITH CNN”, JESD, vol. 8, no. 5, pp. 52–57, Dec. 2020, doi: 10.21923/jesd.828457.
ISNAD
Danışman, Taner - Üncü, Yiğit Ali - Karaçaylı, Deniz - Bilge, Uğur - Birge, Özer - Bakır, Mehmet - Göksu, Mehmet - Şimşek, Tayup - Canpolat, Murat. “PREDICTING THE LOCATION OF THE UTERINE CERVICAL OS FROM 2D IMAGES WITH CNN”. Mühendislik Bilimleri ve Tasarım Dergisi 8/5 (December 1, 2020): 52-57. https://doi.org/10.21923/jesd.828457.
JAMA
1.Danışman T, Üncü YA, Karaçaylı D, Bilge U, Birge Ö, Bakır M, Göksu M, Şimşek T, Canpolat M. PREDICTING THE LOCATION OF THE UTERINE CERVICAL OS FROM 2D IMAGES WITH CNN. JESD. 2020;8:52–57.
MLA
Danışman, Taner, et al. “PREDICTING THE LOCATION OF THE UTERINE CERVICAL OS FROM 2D IMAGES WITH CNN”. Mühendislik Bilimleri Ve Tasarım Dergisi, vol. 8, no. 5, Dec. 2020, pp. 52-57, doi:10.21923/jesd.828457.
Vancouver
1.Taner Danışman, Yiğit Ali Üncü, Deniz Karaçaylı, Uğur Bilge, Özer Birge, Mehmet Bakır, Mehmet Göksu, Tayup Şimşek, Murat Canpolat. PREDICTING THE LOCATION OF THE UTERINE CERVICAL OS FROM 2D IMAGES WITH CNN. JESD. 2020 Dec. 1;8(5):52-7. doi:10.21923/jesd.828457

Cited By