A Determination Method of Dopamine or Epinephrine by Conducting Polymers : The Electrochemical Impedance Spectroscopy

Abstract

In this study, it was reported that the preparation and characterization of capacitive sensor based on conducting polymer for detection of dopamine and/or epinephrine by impedimetric method, electrochemical impedance spectroscopy. Pt electrodes coated with poly(Cz) and poly(In) in different electrolyte solution by electropolymerization. NaClO4-ACN electrolyte solution was selected as suitable electrolyte solution, due to high capacitive behavior. The usage of EIS technique for the determination of DA or EP in presence of AA was investigated. For this reason, the measurement EIS of prepared polymer coated electrodes in suitable conditions was performed by immersed in different concentrations (from 10^-9M to 10^-6M) of DA or EP in presence of 10^-4 M of AA at pH 7. It was found that Poly(Cz) coated electrode was a more convenient biosensor for determination of EP by EIS method than Poly(In) and for DA determination. Also, the EIS method was able to use as the readout of Poly(Cz) coated electrode as a biosensor for the determination of EP.   

Keywords

• Electro polymerization,Determination,Dopamine,Epinephrine and Impedance .

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