2.-4. parmak uzunlukları oranı ile ultrasonografik üretrovajinal alan ölçümlerinin korelasyonu

Abstract

Amaç: İkinci- dördüncü parmak uzunlukları oranı (2D:4D), fetal yaşamda androjen maruziyetinin bir göstergesi olarak kullanılır. Ürogenital sistem ve parmak uzunluğunun farklılaşmasının Homeobox genleri (HoxA ve HoxD) tarafından kontrol edildiği bilinmektedir. Bu nedenle parmakların antropometrik özellikleri ile bağlantılı faktörlerin genetik ve hormonal temele bağlı olarak ürogenital anatomi ile ilişkili olması beklenir. Bu çalışmanın amacı 2D:4D oranı ile üretrovajinal aralık ölçümleri arasındaki korelasyonun değerlendirilmesidir. Materyal ve yöntem: Bu prospektif kohort çalışmada üreme dönemindeki otuz bir kadının sonuçları değerlendirilmiştir. Ellerin dijital antropometrik ölçümler ve üretrovajinal aralığın ultrasonografik ölçümleri yapılmış, bu parametreler arasındaki korelasyon değerlendirildi. Bulgular: Sağ ve sol el 2D:4D oranı ile üretrovajinal boşluk uzunluğu arasında anlamlı negatif korelasyon saptandı (sırasıyla p=0,007 ve p=0,003). Proksimal, orta ve distal segmentteki üretrovajinal boşluğun kalınlığı da her iki el için 2D:4D oranı ile negatif korelasyon gösterdi. Sonuç: Mevcut çalışmanın bulguları 2D:4D oranı ile üretrovajinal boşluk ölçümleri arasında bir ilişki olduğunu göstermiştir. Bu verilerden elde edilen içgörüler, 2D:4D ve kadın genital anatomisi arasındaki ilişki hakkında gelecekteki araştırmalar için bir temel teşkil edecektir. Bu çalışma ayrıca UVS' nin anatomik özelliklerine ilişkin ek kanıtlar sağlamıştır.

Keywords

• parmak oranı
• kadın
• genital anatomi
• üretrovajinal boşluk

Correlation between 2nd to 4th digit ratios and ultrasonographic measurements of urethrovaginal spa

Abstract

Aim: Second to fourth digit (2D:4D) ratio is used as an indicator of androgen exposure in fetal life. It is known that the differentiation of urogenital tract and finger length are both controlled by Homeobox genes (HoxA and HoxD). Therefore, factors that are connected with anthropometric characteristics of fingers are expected to be in relation with urogenital anatomy, depending on genetic and hormonal basis. Aim of the study is to evaluate the correlation between 2D:4D ratio and urethrovaginal space measurements. Materials and methods: In this prospective cohort study, digital anthropometric measurements of hands and ultrasonographic measurements of urethrovaginal space were evaluated and the correlation between these parameters were assessed in a sample of women in reproductive period. Results: A significant negative correlation was detected between both right and left hand 2D: 4D ratio and length of urethrovaginal space (p=0.007 and p=0.003, respectively). The thickness of urethrovaginal space at proximal, middle and distal segment was also correlated negatively with 2D:4D ratio for both hands. Conclusion: The findings of the current study have shown a correlation between 2D: 4D ratio and urethrovaginal space measurements. The insights gained from these data will serve as a base for future research about the relationship between 2D:4D and female genital anatomy. The present study has also provided additional evidence with respect to anatomical features of UVS.

Keywords

• digit ratio
• female
• genital anatomy
• urethrovaginal space

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