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Fetal taşikardi term gebeliklerde asemptomatik COVID-19'a işaret edebilir: Olgu serisi

Year 2023, , 1676 - 1680, 30.03.2023
https://doi.org/10.38136/jgon.1076215

Abstract

Coronavirüs Hastalığı 2019 (COVID-19) viral kaynaklı bir pandemidir. Hastalığın olumsuz gebelik sonuçlarıyla doğrudan ilişkili olmadığı savunulmakla birlikte, çalışmalarda COVID-19'lu gebeliklerde fetal distres oarnının arttığı gösterilmiştir. Bu vaka serisinde, asemptomatik COVID-19'un eşlik ettiği fetal taşikardi vakalarını sunmayı amaçladık. Bu çalışmada, rutin gebelik takibi için başvuran ve termed gebeliği olan 3 hastada, fetal taşikardi temelinde fetal distres geliştiği tespit edildi ve acil sezaryen ile doğum gerçekleştirildi. Gebelerden hiçbirinin kronik hastalığı veya COVID-19’lu bir vaka ile yakın temas öyküsü yoktu. Tam kan sayımı ve kan serumu analizleri normaldi. Tüm hastalara asemptomatik COVID-19 teşhisi konuldu ve yenidoğanlardan 1 tanesinde de COVID-19 pozitif çıktı. Bu doğrultuda, fetal taşikardi tespit edilen gebeliklerde, hastalık semptomları olmasa bile COVID-19 ihtimali akılda tutulmalıdır. Fetal distres, obstetrik bir acildir. Bu nedenle olası olumsuz maternal ve neonatal sonuçlarla başa çıkabilmek için COVID-19'un potansiyel tehditleri göz önünde bulundurulmalıdır.

References

  • 1. Yang Z, Wang M, Zhu Z, Liu Y. Coronavirus disease 2019 (COVID-19) and pregnancy: a systematic review. J Matern Fetal Neonatal Med. 2020:1-4.
  • 2. Gravett C, Eckert LO, Gravett MG, Dudley DJ, Stringer EM, Mujobu TB, et al. Non-reassuring fetal status: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data. Vaccine. 2016;34(49):6084-92.
  • 3. Erol Koc EM, Findik RB, Akkaya H, Karadag I, Tokalıoğlu EO, Tekin OM. Comparison of hematological parameters and perinatal outcomes between COVID-19 pregnancies and healthy pregnancy cohort. J Perinat Med. 2020;49(2):141-147.
  • 4. Ashraf MA, Keshavarz P, Hosseinpour P, Erfani A, Roshanshad A, Pourdast A, et al. Coronavirus Disease 2019 (COVID-19): A Systematic Review of Pregnancy and the Possibility of Vertical Transmission. J Reprod Infertil. 2020;21(3):157-68.
  • 5. Zhu H, Wang L, Fang C, Peng S, Zhang L, Chang G, et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020;9(1):51-60.
  • 6. Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020;395(10226):809-15.
  • 7. Ducsay CA, Goyal R, Pearce WJ, Wilson S, Hu XQ, Zhang L. Gestational Hypoxia and Developmental Plasticity. Physiol Rev. 2018;98(3):1241-334.
  • 8. Ng WF, Wong SF, Lam A, Mak YF, Yao H, Lee KC, et al. The placentas of patients with severe acute respiratory syndrome: a pathophysiological evaluation. Pathology. 2006;38(3):210-8.
  • 9. Schoenmakers S, Snijder P, Verdijk R, Kuiken T, Kamphuis S, Koopman L, et al. SARS-CoV-2 placental infection and inflammation leading to fetal distress and neonatal multi-organ failure in an asymptomatic woman. J Pediatric Infect Dis Soc. 2021;10(5):556-561.
  • 10. Sharps MC, Hayes DJL, Lee S, Zou Z, Brady CA, Almoghrabi Y, et al. A structured review of placental morphology and histopathological lesions associated with SARS-CoV-2 infection. Placenta. 2020;101:13-29.
  • 11. Li M, Chen L, Zhang J, Xiong C, Li X. The SARS-CoV-2 receptor ACE2 expression of maternal-fetal interface and fetal organs by single-cell transcriptome study. PLoS One. 2020;15(4):e0230295.
  • 12. Zamaniyan M, Ebadi A, Aghajanpoor S, Rahmani Z, Haghshenas M, Azizi S. Preterm delivery, maternal death, and vertical transmission in a pregnant woman with COVID-19 infection. Prenat Diagn. 2020;40(13):1759-1761.

Fetal tachycardia may indicate to asymptomatic COVID-19 at term pregnancies: A case series

Year 2023, , 1676 - 1680, 30.03.2023
https://doi.org/10.38136/jgon.1076215

Abstract

Coronavirus Disease 2019(COVID-19)pandemics is a novel viral infection.The disease was not found as directly related with adverse pregnancy outcomes;however,the incidence of fetal distress has shown to be increased in pregnancies with COVID-19.This case series aimed to present fetal tachycardia cases with accompanying asymptomatic COVID-19.This study reported three women with term pregnancies applied for routine pregnancy follow-up were detected to develop fetal distress at the basis of fetal tachycardia and delivered through emergency C-section.None of them had any chronic disease or the history of close contact.The complete blood count and blood serum analyses were normal.All patients were diagnosed to have asymptomatic COVID-19,of which one neonate was positive for COVID-19. COVID-19 should be considered in fetal tachycardia cases, even in the absence of disease symptoms.Fetal distress is an obstetric emergency;therefore,the potential threats of COVID-19 should be kept in mind to be able to cope with possible adverse maternal and neonatal outcomes.

References

  • 1. Yang Z, Wang M, Zhu Z, Liu Y. Coronavirus disease 2019 (COVID-19) and pregnancy: a systematic review. J Matern Fetal Neonatal Med. 2020:1-4.
  • 2. Gravett C, Eckert LO, Gravett MG, Dudley DJ, Stringer EM, Mujobu TB, et al. Non-reassuring fetal status: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data. Vaccine. 2016;34(49):6084-92.
  • 3. Erol Koc EM, Findik RB, Akkaya H, Karadag I, Tokalıoğlu EO, Tekin OM. Comparison of hematological parameters and perinatal outcomes between COVID-19 pregnancies and healthy pregnancy cohort. J Perinat Med. 2020;49(2):141-147.
  • 4. Ashraf MA, Keshavarz P, Hosseinpour P, Erfani A, Roshanshad A, Pourdast A, et al. Coronavirus Disease 2019 (COVID-19): A Systematic Review of Pregnancy and the Possibility of Vertical Transmission. J Reprod Infertil. 2020;21(3):157-68.
  • 5. Zhu H, Wang L, Fang C, Peng S, Zhang L, Chang G, et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020;9(1):51-60.
  • 6. Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020;395(10226):809-15.
  • 7. Ducsay CA, Goyal R, Pearce WJ, Wilson S, Hu XQ, Zhang L. Gestational Hypoxia and Developmental Plasticity. Physiol Rev. 2018;98(3):1241-334.
  • 8. Ng WF, Wong SF, Lam A, Mak YF, Yao H, Lee KC, et al. The placentas of patients with severe acute respiratory syndrome: a pathophysiological evaluation. Pathology. 2006;38(3):210-8.
  • 9. Schoenmakers S, Snijder P, Verdijk R, Kuiken T, Kamphuis S, Koopman L, et al. SARS-CoV-2 placental infection and inflammation leading to fetal distress and neonatal multi-organ failure in an asymptomatic woman. J Pediatric Infect Dis Soc. 2021;10(5):556-561.
  • 10. Sharps MC, Hayes DJL, Lee S, Zou Z, Brady CA, Almoghrabi Y, et al. A structured review of placental morphology and histopathological lesions associated with SARS-CoV-2 infection. Placenta. 2020;101:13-29.
  • 11. Li M, Chen L, Zhang J, Xiong C, Li X. The SARS-CoV-2 receptor ACE2 expression of maternal-fetal interface and fetal organs by single-cell transcriptome study. PLoS One. 2020;15(4):e0230295.
  • 12. Zamaniyan M, Ebadi A, Aghajanpoor S, Rahmani Z, Haghshenas M, Azizi S. Preterm delivery, maternal death, and vertical transmission in a pregnant woman with COVID-19 infection. Prenat Diagn. 2020;40(13):1759-1761.
There are 12 citations in total.

Details

Primary Language English
Subjects Obstetrics and Gynaecology
Journal Section Case Reports
Authors

Esin Merve Erol Koç 0000-0001-7686-9149

Hatice Akkaya 0000-0002-9613-1712

Publication Date March 30, 2023
Submission Date February 21, 2022
Acceptance Date July 17, 2022
Published in Issue Year 2023

Cite

Vancouver Erol Koç EM, Akkaya H. Fetal tachycardia may indicate to asymptomatic COVID-19 at term pregnancies: A case series. JGON. 2023;20(1):1676-80.