Plasenta previa olgularında plasenta patolojilerinin değerlendirilmesi

Abstract

Amaç: Çalışmamızın birincil amacı, plasenta previanın (PP) altında yatan plasental patolojileri değerlendirmektir. Gereçler ve Yöntem: Üçüncü basamak bir merkezde PP tanısı alan hastaların iki yılı aşkın verileri retrospektif olarak edinildi. Rutin olarak, PP tanısı konulan hastaların plasentaları patolojik incelemeye gönderilir. Hastaların klinikodemografik verileri kaydedildi. Plasental patolojik bulgular maternal vasküler lezyonlar, fetal vasküler lezyonlar, inflamatuar durumlar, umbilikal kord bulguları ve normal olmak üzere 5 ana grupta sınıflandırılıp değerlendirildi. Ayrıca hastaların hastaneye yatış anındaki tam kan sayımı sonuçları ve yenidoğan sonuçları kaydedildi. Bulgular: Çalışmaya PP tanısı alan 32 hasta dahil edildi. Medyan yaş 34 (22-42), medyan gravida 3 (1-6) idi. PP hastalarının yaklaşık yarısında patolojik bulgu olarak maternal vasküler lezyonlar izlendi (43.75 %). Sırasıyla 10 hastada (32.25 %) enflamasyon, 8 hastada (25 %) umbilikal kord bulguları ve 2 hastada (6.25 %) fetal vasküler lezyon gözlendi. 3 hastada normal plasenta olduğu bildirildi. Ayrıca hastaların medyan nötrofil, nötrofil lenfosit oranı ve beyaz küre sayımı hastaneye yatış anında yüksek bulundu. Sonuç: Maternal vasküler lezyonlar ve inflamasyon, PP hastalarında en sık saptanan plasental patolojik raporlardı. Ancak komplike olmayan gebeliklerin plasentalarını da içeren çalışmalar patolojik durumu fizyolojik durumdan ayırt etmek için literatüre ışık tutacaktır.

Keywords

• Plasenta previa
• patoloji
• maternal vasküler lezyonlar
• inflamasyon

Evaluation of placental pathologies in cases of placenta previa

Abstract

Objective: The primary aim of our study was to evaluate the underlying placental pathologies of placenta previa (PP). Materials and Methods: Over two years data of patients diagnosed to be PP in a tertiary center were obtained retrospectively. Routinely, the placentas of patients diagnosed to be PP were sent for pathological examination. Clinicodemographic data of the patients were recorded. The placental pathological findings were classified and evaluated in 5 main groups: maternal vascular lesions, fetal vascular lesions, inflammatory situations, umbilical cord findings, and normal. Additionally, complete blood count results at admission time for hospitalization and the outcomes of the neonates were recorded. Results: Thirty-two patients diagnosed to be PP were included in the study. The median age was 34 (22-42), and the median gravidity number was 3 (1-6). Maternal vascular lesions were observed in nearly half of the PP patients as a pathological finding (43.75 %). Inflammation was observed in 10 patients (31.25 %), umbilical cord findings in 8 patients (25.0 %), and fetal vascular lesions in 2 patients (6.25 %), respectively. 3 patients were reported to have normal placentas. In addition, the median neutrophile, neutrophile lymphocyte ratio, and white blood count were found to be high at admission time for hospitalization Conclusion: Maternal vascular lesions and inflammation were the most common detected placental pathological reports in PP patients. However, studies including the placentas of uncomplicated pregnancies will shed light on the literature to distinguish the pathological condition from the physiological condition.

Keywords

• Placenta previa
• pathology
• maternal vascular lesions
• inflammation

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