Toplanan Oosit Sayısı ve Olgun Oosit Oranı IVF Sonuçlarını Etkiler mi?

Year 2023, , 1596 - 1602, 30.03.2023

Mehmet Caner Özer , Ayten Türkkanı , Derya Özdemir Taş , Şebnem Özyer , Mustafa Turan , Nafiye Yılmaz , Özlem Moraloğlu Tekin

https://doi.org/10.38136/jgon.1176830

Abstract

Amaç: Bu çalışmanın amacı, tek fresh embriyo transferinde elde edilen oosit sayısı ve olgun oosit oranının IVF sonuçları üzerindeki etkilerini araştırmaktır.
Gereç ve Yöntemler: Toplanan oosit sayısı ve matür oosit oranı açısından iki ana grup oluşturuldu. 561 IVF siklusunda elde edilen oosit sayısına göre 0-5 (n=175) oosit grup 1, 6-10 (n=214) oosit grup 2, 11-15 (n=121) oosit grup 3 olarak belirlendi. grup 3 ve grup 4 olarak 16 veya daha fazla oosit (n=51). Matür oosit (metafaz II, MII oosit) oranına göre grup 1A (n=338) %76-100 matür oosit, grup 2A (n=150) %75-50 matür oosit ve grup 3A (n) olmak üzere üç grup oluşturuldu. =73) %50'den az olgun oosit.
Bulgular: Toplanan oosit sayısı ile fertilizasyon oranı negatif korelasyon gösterirken, 6-10 oosit grubunda Β-hCG pozitifliği ve klinik gebelik oranlarının daha iyi olduğu gözlendi. Ortalama yaş, bazal LH ve ovulasyonun tetiklendiği gün E2 seviyeleri ve fertilizasyon oranı, üç olgun oosit oranı grubu arasında önemli ölçüde farklıydı.
Sonuç: Sonuç olarak, toplanan oosit sayısından bağımsız olarak kohorttaki MII oosit oranları IVF sonuçlarını etkilemedi.

Keywords

Oosit sayısı, Olgun oosit oranı, Fresh tek embriyo transferi

Do the Number of Oocytes Retrieved and Mature Oocyte Rate in the Cohort Affect IVF Results?

Abstract

Aim: The aim of this study was to investigate the effects of the number of oocytes retrieved and rate of mature oocytes on IVF outcomes in single fresh embryo transfer.
Materials and Medhods: Two main groups were formed regarding number of oocytes retrieved and mature oocyte rate. According to the number of oocytes retrieved in 561 IVF cycles, 0-5 (n=175) oocytes were determined as group 1, 6-10 (n=214) oocytes as group 2, 11-15 (n=121) oocytes as group 3 and 16 or more oocytes as group 4 (n=51). Regarding mature oocyte (metaphase II, MII oocyte) rate, three groups were formed: group 1A (n=338) 76-100% mature oocytes, group 2A (n=150) 75-50% mature oocytes, and group 3A (n=73) less than 50% mature oocytes.
Results: The number of oocytes retrieved was negatively correlated fertilization rate, whereas Β-hCG positivity and clinical pregnancy rates were observed to be better in the 6-10 oocytes group. The mean age, basal LH, and ovulation trigger day E2 levels, and fertilization rate were differed significantly between three groups of mature oocyte rate.
Conclusion: In conclusion, MII oocyte rates in the cohort, regardless of the number of oocytes retrieved, did not affect IVF outcomes.

Keywords

Number of oocyte, Mature oocyte rate, Fresh single embryo transfer.

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