Clinical Research

The role of the ratio of first trimester CRL (crown rump length) measurement to NT (nuchal translucency) measurements in predicting early-onset fetal growth restriction (FGR)

Volume: 21 Number: 1 April 1, 2024
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The role of the ratio of first trimester CRL (crown rump length) measurement to NT (nuchal translucency) measurements in predicting early-onset fetal growth restriction (FGR)

Abstract

Objective: Our aim is to evaluate the role of the ratio of first-trimester CRL (crown rump length) measurement to NT (nuchal translucency) measurements in predicting early-onset fetal growth restriction (FGR) and to contribute to the existing literature. Methods: In the present case-control study, fetuses with early-onset FGR were compared to a frequency matched low risk control group. This study was conducted in the perinatology clinic of Ankara Bilkent City Hospital between 2020 and 2023. Maternal age, gravidity, parity, crown-rump length (CRL), and nuchal translucency (NT) measurements were compared between pregnant women with early onset FGR (n=39) and pregnant women without FGR (n=50). Results: The mean age of pregnant women with FGR who participated in the study was 27.1±0.8, and the mean age of pregnant women without FGR was 26.3±0.6, and no statistically significant difference was found between the two groups (p=0.4)). Mean CRL was 54.98±1.08 mm in the group with FGR and 56.99±1.11 mm in the group without FGR; there was no significant difference between the two groups (p=0.2). The NT value was 1.11 ± 0.04 mm in the FGR group and 1.13 ± 0.02 mm in the without FGR group, there was no significant difference between the two groups (p=0.73). The mean CRL/NT ratio was 52.00±2.33 in the group with early onset FGR and 51.46±1.48 in the group without FGR and there was no statistically significant difference between the two groups (p=0.83). When the early developing FGR group is evaluated within itself, the mean age at diagnosis was 31.7±0.3 weeks. EFW mean percentile at diagnosis was 4.5±0.6 and ac percentile was 2.9±0.4. The mean umbilical artery systole/diastole ratio (UA-SD) was 2.9±0.16 and the mean umbilical artery pulsatility index (UA-PI) was 1.02±0.05. Conclusion: Crown-rump length to nuchal translucency ratio is not clinically useful to predict early-onset FGR.

Keywords

References

  1. 1. Gardosi J, Chang A, Kalyan B, Sahota D, Symon- ds E. Customised antenatal growth charts. The Lancet. 1992;339(8788):283-7. 2. Tudehope D, Vento M, Bhutta Z, Pachi P. Nut- ritional requirements and feeding recommendations for small for gestational age infants. The Journal of Pediatrics. 2013;162(3):S81-S9. 3. Lapillonne A, Braillon P, Claris O, Chatelain P, Delmas P, Salle B. Body composition in appropriate and in small for gestational age infants. Acta Paediatrica. 1997;86(2):196-200.

Details

Primary Language

English

Subjects

Obstetrics and Gynaecology

Journal Section

Clinical Research

Publication Date

April 1, 2024

Submission Date

November 29, 2023

Acceptance Date

January 25, 2024

Published in Issue

Year 2024 Volume: 21 Number: 1

APA
Şahin, R., Tanacan, A., Şerbetçi, H., Özkavak, O. O., Haksever, M., Başarır, M. U., Kara, Ö., & Sahin, D. (2024). The role of the ratio of first trimester CRL (crown rump length) measurement to NT (nuchal translucency) measurements in predicting early-onset fetal growth restriction (FGR). Jinekoloji-Obstetrik Ve Neonatoloji Tıp Dergisi, 21(1), 28-32. https://doi.org/10.38136/jgon.1397142
AMA
1.Şahin R, Tanacan A, Şerbetçi H, et al. The role of the ratio of first trimester CRL (crown rump length) measurement to NT (nuchal translucency) measurements in predicting early-onset fetal growth restriction (FGR). Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi. 2024;21(1):28-32. doi:10.38136/jgon.1397142
Chicago
Şahin, Refaettin, Atakan Tanacan, Hakkı Şerbetçi, et al. 2024. “The Role of the Ratio of First Trimester CRL (crown Rump Length) Measurement to NT (nuchal Translucency) Measurements in Predicting Early-Onset Fetal Growth Restriction (FGR)”. Jinekoloji-Obstetrik Ve Neonatoloji Tıp Dergisi 21 (1): 28-32. https://doi.org/10.38136/jgon.1397142.
EndNote
Şahin R, Tanacan A, Şerbetçi H, Özkavak OO, Haksever M, Başarır MU, Kara Ö, Sahin D (April 1, 2024) The role of the ratio of first trimester CRL (crown rump length) measurement to NT (nuchal translucency) measurements in predicting early-onset fetal growth restriction (FGR). Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 21 1 28–32.
IEEE
[1]R. Şahin et al., “The role of the ratio of first trimester CRL (crown rump length) measurement to NT (nuchal translucency) measurements in predicting early-onset fetal growth restriction (FGR)”, Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi, vol. 21, no. 1, pp. 28–32, Apr. 2024, doi: 10.38136/jgon.1397142.
ISNAD
Şahin, Refaettin - Tanacan, Atakan - Şerbetçi, Hakkı - Özkavak, Osman Onur - Haksever, Murat - Başarır, Mehmet Utku - Kara, Özgür - Sahin, Dilek. “The Role of the Ratio of First Trimester CRL (crown Rump Length) Measurement to NT (nuchal Translucency) Measurements in Predicting Early-Onset Fetal Growth Restriction (FGR)”. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 21/1 (April 1, 2024): 28-32. https://doi.org/10.38136/jgon.1397142.
JAMA
1.Şahin R, Tanacan A, Şerbetçi H, Özkavak OO, Haksever M, Başarır MU, Kara Ö, Sahin D. The role of the ratio of first trimester CRL (crown rump length) measurement to NT (nuchal translucency) measurements in predicting early-onset fetal growth restriction (FGR). Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi. 2024;21:28–32.
MLA
Şahin, Refaettin, et al. “The Role of the Ratio of First Trimester CRL (crown Rump Length) Measurement to NT (nuchal Translucency) Measurements in Predicting Early-Onset Fetal Growth Restriction (FGR)”. Jinekoloji-Obstetrik Ve Neonatoloji Tıp Dergisi, vol. 21, no. 1, Apr. 2024, pp. 28-32, doi:10.38136/jgon.1397142.
Vancouver
1.Refaettin Şahin, Atakan Tanacan, Hakkı Şerbetçi, Osman Onur Özkavak, Murat Haksever, Mehmet Utku Başarır, Özgür Kara, Dilek Sahin. The role of the ratio of first trimester CRL (crown rump length) measurement to NT (nuchal translucency) measurements in predicting early-onset fetal growth restriction (FGR). Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi. 2024 Apr. 1;21(1):28-32. doi:10.38136/jgon.1397142