Future Feasibility Of Nonavalent 9-valent HPV Vaccine in Turkey

Abstract

HPV infection is the most important reason for the development of cervical cancer and HPV type 16 and 18 are responsible for 70% of cervical cancer cases. Bivalent and quadrivalent HPV vaccines are effective against HPV type 16 and 18 among the high risk HPV group, however Nonavalent HPV vaccine provides additional effectiveness against HPV type 31, 33, 45, 52 and 58 among the high risk HPV group. Endemic HPV types detected in Turkey; 16, 51, 31, 52, 56, 39, 58 45, 33 and 18, clearly indicate the need for Nonavalent HPV vaccine for Turkey.

Keywords

• HPV,vaccine,cervical cancer,wart,CIN

Gelecekte Nonavalent 9-valent HPV Aşısının Türkiye İçin Kullanılabilirliği

Abstract

HPV enfeksiyonu servikal kanser gelişimi için en önemli neden olup, serviks kanseri vakalarının yaklaşık %70’i HPV tip 16 ve 18’e bağlı olarak gelişir. İkili ve dörtlü HPV aşıları yüksek riskli HPV grubundan tip 16 ve 18’e karşı etkili iken, Nonavalent HPV aşısı ek olarak yüksek riskli HPV tip 31, 33, 45, 52, ve 58’e karşı da etkinlik gösterir. Türkiye’de endemik görülen HPV tipleri; 16, 51, 31, 52, 56, 39, 58 45, 33 ve 18 dikkate alındığında ülkemiz için Nonavalent HPV aşısına ihtiyaç daha net olarak anlaşılacaktır.

Keywords

• HPV,aşı,serviks kanseri,siğil,CIN

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