Asthma and Pregnancy

Abstract

Aim: Asthma is the most common chronic disease in pregnancy. It affects the quality of life of mother and is together with the perinatal risks. Especially, in mild and severe asthma patients who has frequent asthma exacerbations in pregnancy, risk of low birth weight, preterm delivery and congenital malformations is high. As a result,control of asthma is very important for both mother and fetus.The pregnant woman with asthma must be followed up by obstetrician and chest disease specialist together.

Keywords

• Asthma,pregnancy,treatment

Gebelik ve Astım

Abstract

Astım gebelikte en sık görülen kronik hastalıktır. Annenin yaşam kalitesini etkiler ve perinatal riskleri beraberinde getirir. Özellikle orta ve ağır astımı olanlarda ve gebelikte sık atak geçirenlerde düşük doğum ağırlığı ve erken doğum riski,düşük oranda da olsa konjenital malformasyon riski artmıştır. Bu nedenle gebelikte astımın tam kontrolünün sağlanması anne ve bebek açısından çok önemlidir. Gebe astımlının takibi kadındoğum uzmanları ile göğüs hastalıkları uzmanlarının işbirliği ile yürütülmelidir.

Keywords

• Astım,gebelik,tedavi

References

1. Charlton, R., Hutchison, A., Davis, K. and De Vries, C. Asthma manage- ment in pregnancy. PLoS One 2013;4:8.
2. Kwon HL, Belanger K, Bracken MB. Asthma prevalence among pregnant and childbearing-aged women in the United States: estimates from nati- onal health surveys. Ann Epidemiol 2003;13:317–324.
3. Juniper Ef NM. Effect of pregnancy on asthma: systematic review and meta-analysis. In: Hn C, Schatz MZR (eds) Asthma and immunologi- cal diseases in pregnancy and early infancy. Marcel Dekker, New York, 1993;223–250.
4. Murphy VE, Gibson P, Talbot PI, Clifton VL. Severe asthma exacerbations during pregnancy. Obstet Gynecol 2005;106:1046-54.
5. Dombrowski, Mitchell P.; Schatz, Michael; Wise, Robert; More Asthma during pregnancy. Obstet Gynecol 2004;103:5-12
6. Evelyne R, Louis-Philippe B. Asthma in pregnancy BMJ 2007;334:582– 585.
7. Valet RS, Dupont WD, Mitchel EF, Hartert TV. Betaagonist use as an indi- cator of change in asthma control during pregnancy. Ann Allergy Asthma Immunol 2009;102:352–353.
8. Schatz M, Harden K, Forsythe A et al. The course of asthma during preg- nancy, post partum, and with successive pregnancies: a prospective analysis. J Allergy Clin Immunol 1988;81:509–517.

9. Lao TT, Huengsburg M. Labour and delivery in mothers with asthma. Eur J Obstet Gynecol Reprod Biol 1990;35:183–190.
10. Kircher S, Schatz M, Long L. Variables affecting asthma course during pregnancy. Ann Allergy Asthma Immunol 2002;8:463–466.
11. Dodds L, Armson BA, Alexander S. Use of asthma drugs is less among women pregnant with boys rather than girls. BMJ 1999;318:1011.
12. Kwon HL, Belanger K, Holford TR, Bracken MB. Effect of fetal sex on airway lability in pregnant women with asthma. Am J Epidemiol 2006;16:217–221.
13. Murphy VE, Powell H, Wark PA, et al. A prospective study of respiratory viral infection in pregnant women withand without asthma. Chest 2013; 144: 420–427.
14. Warwick G, Murphy V. Asthma in pregnancy. Obstet Med 2013;6:58–63.
15. Blais L, Forget A. Asthma exacerbations during the first trimester of pregnancy and the risk of congenital malformations among asthmatic women. J Allergy Clin Immunol 2008; 121:1379–1384.
16. Enriquez R, Griffin MR, Carroll KN et al. Effect of maternal asthma and asthma control on pregnancy and perinatal outcomes. J Allergy Clin Im- munol 2007;120:625–630.
17. Murphy, V., Namazy, J., Powell, H., Schatz, M., Chambers, C., Attia, J. et al. A meta-analysis of adverse perinatal outcomes in women with asth- ma. Br J Obstet Gynaecol 2011;118: 1314–1323.
18. Murphy VE, Wang G, Namazy JA, et al. The risk of congenital malformati- ons, perinatal mortality and neonatal hospitalisation among pregnant wo- men with asthma: a systematic review and meta-analysis. BJOG 2013; 120: 812–822.
19. Dombrowski, M. and Schatz, M.; ACOG Committee on Practice Bulletins – Obstetrics ACOG practice bulletin: clinical management guidelines for obstetrician-gynecologists number 90, February 2008: asthma in preg- nancy. Obstet Gynecol 2008;111: 457–464.
20. Firoozi, F., Lemiere, C., Ducharme, F., Beauchesne, M., Perreault, S., Be- rard, A. et al. Effect of maternal moderate to severe asthma on perinatal outcomes. Resp Med 2010;104: 1278–1287.
21. Murphy VE, Gibson PG, Smith R, Clifton VL. Asthma during pregnancy: mechanisms and treatment implications. Eur Respir J 2005;25:731–50.
22. Report NEP Working Group Report on Managing Asthma During Preg- nancy: recommendations for pharmacologic treatment- update 2004. Allergy Clin Immunol 2005;115:34–46.
23. Australia NCO, Asthma management handbook 2007.
24. Morgan MA, Cragan JD, Goldenberg RL, Rasmussen SA, Schulkin J. Management of prescription and nonprescription drug use during preg- nancy. J Matern-Fetal Neonatal Med 2010;23:813–819.
25. Powell, H., Murphy, V., Taylor, D., Hensley, M., McCaffrey, K., Giles, W. et al. Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: a double-blind, randomised controlled trial. Lancet 2011;378: 983–990.
26. Louik C, Schatz M, Hernandez-Diaz S, Werler MM, Mitchell AA. Asthma in pregnancy and its pharmacologic treatment. Annals of allergy, asthma and immunology: official publication of the American College of Allergy, Asthma, and Immunology 2010;105:110–117.
27. Lin S, Munsie JP, Herdt-Losavio ML, et al. Maternal asthma medication use and the risk of selected birth defects. Pediatrics 2012; 129.
28. Wilton LV, Shakir SA. A post-marketing surveillance study of formoterol (Foradil): its use in general practice in England. Drug saf 2002;25:213– 223.
29. Guo JJ, Tsai K, Kelton CM, Bian B, Wigle PR. Risk of serious asthma exacerbations associated with long-acting beta agonists among patients with asthma: a retrospective cohort study. Ann Allergy Asthma Immunol 2011;106:214–222.
30. Breton, M., Beauchesne, M., Lemiere, C., Rey, E., Forget, A. and Bla- is, L. Risk of perinatal mortality associated with inhaled corticosteroid use for the treatment of asthma during pregnancy. J AllergyClin Immunol 2010;126: 772–777.
31. Cossette, B., Forget, A., Beauchesne, M., Rey, E., Lemiere, C., Larivee, P. et al. Impact of maternal use of asthma-controller therapy on perinatal outcomes. Thorax 2013;68: 724–730.
32. Breton, M., Beauchesne, M., Lemiere, C., Rey, E., Forget, A. and Bla- is, L. Risk of perinatal mortality associated with inhaled corticosteroid use for the treatment of asthma during pregnancy. J AllergyClin Immunol 2010;126: 772–777.
33. Bracken, M., Triche, E., Belanger, K., Saftlas, A., Beckett, W. and Le- aderer, B. (2003) Asthma symptoms, severity, and drug therapy: a prospective study of effects on 2205 pregnancies. Obstet Gynecol 102: 739–752.
34. Schatz, M., Dombrowski, M., Wise, R., Momirova, V., Landon, M., Mabie, W. et al.; Maternal-Fetal Medicine Units Network; The National Institute of Child Health and Development, National Heart, Lung and Blood Institute. The relationship of asthma medication use to perinatal outcomes. J Al- lergy Clin Immunol 2004;113: 1040–1045.
35. Sn Gonzalez-Diaz GCC, Galindo Rodrı´guez G et al. Asthma and pregnancy-comorbid and coexisting. Global Adv Res J Med Med Sci 2012;1:292–303.
36. Laboratories MR. Sixth annual report on exposure during pregnancy from the Merck Pregnancy Registry for Singulair covering the period from Feb- ruary 20, 1998 through July, 2005.
37. National Heart L, And Blood Institute. Naepp expert panel report. Expert panel report 3: guidelines for the diagnosis and management of asthma: full report. Working Group Report on managing asthma during pregnan- cy: recommendations for pharmacologic treatment-update 2007.
38. British Thoracic Society Scottish Intercollegiate Guidelines N. British gu- ideline on the management of asthma. Thorax 2008;63(Suppl 4).
39. Dombrovski M. Asthma and pregnancy. Obstet Gynecol 2006;108:667– 681.