The Evaluation of the Relation Between Maternal Hemoglobin, Hematocrit and Systemic Arterial Pressure and Newborn Weight

Abstract

Aim: In the present study, we aimed to investigate the effect of maternal arterial pressure and maternal hematologic parameters on newborn weight.Material and Methods: The data belonged to the patients who delivered the babies in Gaziosmanpasa University Department of Gynecology and Obstetrics delivery room were evaluated retrospectively in the present study. Age, delivery history, week of delivery, weight of newborn, hemoglobin-hematocrit values of the mother, systolic-diastolic arterial pressure and mean arterial pressure of the patients were obtained from the records. The percentiles of the newborns were grouped as 0.05 .Conclusion: We suggested that screening the maternal hemoglobin, hematocrit and arterial pressure values with the evaluation of maternal medical, obstetric history and additional risk factors may be more efficient in detecting the low birth weight newborns.

Keywords

• Maternal hemoglobin,hematocrit,blood pressure,low birth weight

Maternal Hemoglobin, Hematokrit ve Sistemik Arteriyel Basınç ile Yenidoğan Kilosu Arasındaki İlişkinin Değerlendirilmesi

Abstract

Amaç: Bu çalışmadaki amacımız, maternal arteriel basınç ve maternal hematolojik durumun yenidoğanın kilosu üzerine olan etkisini araştırmaktır.Gereç ve Yöntemler: Bu çalışmada, Gaziosmanpaşa Üniversitesi Kadın Hastalıkları ve Doğum Anabilim Dalı doğum salonuna Kasım 2013 ve Mayıs 2015 tarihleri arasında doğum eylemi başlamış olmasından dolayı yatan hastaların dosyalarının retrospektif olarak taranması ile elde edilen veriler kullanıldı. Dosyalardan hastaların yaşları, gebelik öyküleri, doğum haftası, yenidoğanın kilosu, annenin hemoglobin-hemotokrit değerleri, sistolik-diastolik arteriyel tansiyon ve ortalama arter basıncı değerleri elde edildi. Yenidoğanın kilo persantilleri 0.05 .Sonuç: Maternal hemoglobin, hemotokrit ve arteriyel basınç değerleri ile maternal medikal, obstetrik öykülerin ve diğer risk faktörlerinin birlikte değerlendirilmesi ile yapılan taramanın, düşük doğum ağırlıklı bebeklerin belirlenmesinde daha etkin olabileceğini düşünmekteyiz.

Keywords

• Maternal hemoglobin,hematokrit,kan basıncı,düşük doğum ağırlığı

References

1. Cohen JM, Beddaoui M, Kramer MS, Platt RW, Basso O, Kahn SR. Mater- nal Antioxidant Levels in Pregnancy and Risk of Preeclampsia and Small for Gestational Age Birth: A Systematic Review and Meta-Analysis. PLoS One 2015;10:0135192.
2. Lindqvist PG, Molin J. Does antenatal identification of small-for-gestati- onal age fetuses significantly improve their outcome? Ultrasound Obstet Gynecol 2005;25:258-64.
3. Brabin BJ, Ginny M, Sapau J, Galme K, Paino J. Consequences of ma- ternal anaemia on outcome of pregnancy in a malaria endemic area in Papua New Guinea. Ann Trop Med Parasitol 1990;84:11-24.
4. Duthie SJ, King PA, To WK, Lopes A, Ma HK. A case controlled study of pregnancy complicated by severe maternal anaemia. Aust N Z J Obstet Gynaecol 1991;31:125-7.
5. Klebanoff MA, Shiono PH, Selby JV, Trachtenberg AI, Graubard BI. Ane- mia and spontaneous preterm birth. Am J Obstet Gynecol 1991;164:59- 63.
6. Lieberman E, Ryan KJ, Monson RR, Schoenbaum SC. Association of maternal hematocrit with premature labor. Am J Obstet Gynecol 1988;159:107-14.
7. Rusia U, Madan N, Agarwal N, Sikka M, Sood SK. Effect of maternal iron deficiency anaemia on foetal outcome. Indian J Pathol Microbiol 1995;38:273-9.
8. Bondevik GT, Lie RT, Ulstein M, Kvåle G. Maternal hematological status and risk of low birth weight and preterm delivery in Nepal.Acta Obstet Gynecol Scand 200;80:402-8.

9. Bais JM, Eskes M, Pel M, Bonsel GJ, Bleker OP. Effectiveness of detecti- on of intrauterine growth retardation by abdominal palpation as screening test in a low risk population: an observational study. Eur J Obstet Gynecol Reprod Biol 2004;116:164-9.
10. Lindhard A, Nielsen PV, Mouritsen LA, Zachariassen A, Sorensen HU, Roseno H. The implications of introducing the symphyseal-fundal hei- ght-measurement. A prospective randomized controlled trial. Br J Obstet Gynaecol 1990;97:675-80.
11. Lesmes C, Gallo DM, Panaiotova J, Poon LC, Nicolaides KH. Prediction of small-for-gestational-age neonates: screening by fetal biometry at 19- 24 weeks Ultrasound Obstet Gynecol 2015;46:198-207.
12. Fadigas C, Guerra L, Garcia-Tizon Larroca S, Poon LC, Nicolaides KH. Prediction of small-for-gestational-age neonates: screening by uterine artery Doppler and mean arterial pressure at 35-37 weeks. Ultrasound Obstet Gynecol 2015;45:715–21.
13. Murphy JF, O’Riordan J, Newcombe RG, Coles EC, Pearson JF Relation of haemoglobin levels in first and second trimesters to outcome of preg- nancy. Lancet 1986;1:992-5.
14. Brabin BJ, Hakimi M, Pelletier D. An analysis of anemia and pregnan- cy-related maternal mortality. J Nutr 2001;131:604-14.
15. Shobeiri F, Begum K, Nazari M. A prospective study of maternal hemog- lobin status of Indian women during pregnancy and pregnancy outcome. Nutr Res 2006;26:209–13.
16. Bodnar LM, Siega-Riz AM, Arab L, Chantala K, McDonald T. Predictors of pregnancy and postpartum haemoglobin concentrations in low-income women. Public Health Nutr 2004;7:701–11.
17. Rasmussen S, Bergsjo P, Jacobsen G, Haram K, Bakketeig LS. Haemog- lobin and serum ferritin in pregnancy--correlation with smoking and body mass index. Eur J Obstet Gynecol Reprod Biol 2005;12:27–34.
18. Fraser D, Cooper MA, Myles MF. Myles Textbook for Midwives.Edinbur- gh; New York: Churchill Livingstone; 2009.
19. Lozoff B, Georgieff MK. Iron deficiency and brain development. Semin Pediatr Neurol 2006;13:158–65.
20. Dane B, Arslan N, Batmaz G, Dane C.Annede anemi yenidoğanı etkiler mi? Türk Ped 2013; 195-9.
21. Alizadeh L, Raoofi A, Salehi L, Ramzi M. Impact of maternal hemoglo- bin concentration on fetal outcomes in adolescent pregnant women. Iran Red Crescent Med J 2014;16:19670.
22. Şener T, Atar Gürel S, Gürel H, Özalp S, Hassa H, Enünlü T. Kendi Popü- lasyonumuzda Gebelik Yaşına Göre Düşük Ağırlıklı (SGA) Fetus Doğumu İle Sonuçlanan Önemli Risk Faktörleri. Perinatoloji Dergisi 1993;1: 224- 30.
23. Ferraz EM, Gray RH, Cünha TM. Determinants of preterm delivery and int- rauterine growth retardation in North East Brazil. Epidemiol 1990;19:101.
24. Wen SW, Goldenberg RL, Cutter GR, Hoffman HJ, Cliver SP. Intrauterine growth retardation and preterm delivery: Prenatal risk factors in an indi- gent population. Am J Obstet Gynecol. 1990;162:213-8.
25. Yeniel AÖ, Ergenoğlu M, Zeybek B. Preeklamptik gebelerde sistolik-di- yastolik kan basıncı değerleri, idrar protein miktarı ve doppler bulguları- nın perinatal sonuçlara etkisi Ege Journal of Medicine / Ege Tıp Dergisi 2010;49:75-81.
26. Karagiannis G, Akolekar R, Sarquis R, Wright D, Nicolaides KH. Predic- tion of small-for-gestation neonates from biophysical and biochemical markers at 11–13 weeks. Fetal Diagn Ther 2011;29:148–54.
27. Khalil A, Sodre D, Syngelaki A, Akolekar R, Nicolaides KH. Maternal hemodynamics at 11–13 weeks of gestation in pregnancies delivering small for gestational age neonates. Fetal Diagn Ther 2012;32:231–38.
28. Bakker R, Steegers EA, Hofman A, Jaddoe VW. Blood pressure in dif- ferent gestational trimesters, fetal growth, and the risk of adverse birth outcomes: the generation R study. Am J Epidemiol 2011;174:797–806.
29. Churchill D, Perry IJ, Beevers DG. Ambulatory blood pressure in preg- nancy and fetal growth. Lancet 1997;349:7–10.
30. Bakalis S, Stoilov B, Akolekar R, Poon LC, Nicolaides KH. Prediction of small-for-gestational-age neonates: screening by uterine artery Doppler and mean arterial pressure at 30–34 weeks Ultrasound Obstet Gynecol 2015;45:707–14.