The Effect of Leukospermia on Sperm Parameters in Couples With Unexplained Infertility

Abstract

Objective: The association between seminal leukocytes and semen quality is still a matter of debate in the literature. The purpose of this study was to evaluate the effect of leukospermia on semen parameters in unexplained infertile men. Materials and Methods: Semen analysis performed between June 2011 and December 2011 at infertility and in-vitro fertilization IVF clinic of a tertiary research and education hospital in Ankara were studied retrospectively. Results of the male partners of the couples with unexplained infertility were selected. A total of 1637 semen analysis of intrauterine insemination and in-vitro fertilization cycles were included in the study. Results of oligospermic and azospermic males were excluded. Semen parameters of 348 men with leukospermia Group I and 1289 without leukospermia Group II were compared. Results: Leukospermia >106 /mL was found in 348 patients. The prevelance was found to be 21.2% in total. There were no differences between two groups according the age, semen motility and morphology p>0.05 . With regard to semen volume, pH, concentration and total sperm count the difference between two groups were found to be statistically significant p

Keywords

• Leukospermia,unexplained infertility,in-vitro fertilization,intrauterine insemination

Açıklanamayan İnfertil Hastalarda Lökosperminin Sperm Parametreleri Üzerine Etkisi

Abstract

Amaç: Seminal sıvıdaki lökositler ile semen kalitesi arasındaki ilişki literatürde hala bir tartışma konusudur. Bu çalışmada amaç, açıklanamayan infertil hasta grubunda lökosperminin semen parametreleri üzerine etkilerini araştırmaktır. Materyal Metod: Haziran 2011 ile Aralık 2011 tarihleri arasında Ankara’da üçüncü basamak bir eğitim araştırma hastanesinin tüp bebek kliniğinde yapılan semen analizleri retrospektif olarak incelendi. Açıklanamayan infertilite nedeni ile başvuran çiftlerden erkeğe ait sonuçlar bu veriler arasından seçildi. Toplamda intrauterine inseminasyon ve in-vitro fertilizasyon siklusları için hazırlanmış olan 1637 semen analizi çalışmaya dahil edildi. Azospermik ve oligospermik erkekler çalışma dışı bırakıldı. Lökospermi saptanan 348 semen analizi ile Grup I saptanmayan 1289 semen analizi sonucu Grup II karşılaştırıldı. Sonuç: Lökospermi >106 /mL 348 hastada tespit edildi. Prevelansı toplamda %21.2 olarak değerlendirildi. İki grup arasında yaş, semen motilite ve morfolojisi açısından herhangi bir fark saptanmadı. p>0.05 Semen hacmi, pH, konsantrasyon ve total sperm sayısı açısından ise iki grup arasındaki farkı istatistiksel olarak anlamlı olduğu izlendi. p

Keywords

• Lökospermi,açıklanamayan infertilite,in-vitro fertilizasyon,intrauterin inseminasyon

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