CAN 50 G ORAL GLUCOSE CHALLENGE TEST PREDICT INTRAUTERINE GROWTH RETARDATION?

Abstract

Aim: To investigate a likely association between intrauterine growth IUGR retardation and maternal plasma glucose level after 50 g glucose challenge test GCT . Materials and Method: Forty-two pregnant women with IUGR IUGR group and eighty pregnant women with appropriate for gestational age control group enrolled into the study. The results of GCT which performed between 24 to 28 weeks of pregnancy, umbilical arterial Doppler flow velocimetry, birth weights, gestational ages at the time of delivery, and 5th minute APGAR scores were compared between the groups.Statistical analyses were carried out by using the statistical packages for SPSS 15.0 for Windows. Results: Maternal characteristics;average ages, body mass index BMI and gravidity were similar in both two groups. There were statistically significantly lower maternal 1-hour plasma glucose levels and birth weights in IUGR group than control group. The differences of umbilical arterial Doppler flow velocimetry, gestational ages at the time of delivery, 5th minute APGAR scores and admission to the neonatal intensive care unit NICU between the groups were statistically significant. Conclusion: Low 1-hour glucose response to the 50 g glucose challenge is associated with IUGR.

Keywords

• hypoglycemia,50 g glucose challenge test,intrauterine growth retardation,pregnancy

50 GRAM ORAL GLUKOZ TESTİ İLE İNTRAUTERİN GELİŞME KISITLILIĞI TAHMİN EDİLEBİLİR Mİ?

Abstract

Amaç: Intrauterin gelişme geriliği IUGR ile 50 gram oral glukoz testi arasındaki olası ilişkinin araştırılması. Gereçler ve Yöntem: Gebeliği IUGR ile komplike olan 42 kadın IUGR grup ile gebeliğinde gelişme gerililiği olmayan 80 kadın kontrol grup çalışmaya dâhil edildi. 24-28 hafta arası yapılan 50 g oral glukoz testinin sonucu, umbilikal arter Dopler akım değerleri, doğum sırasındaki gebelik haftası ve 5. Dakika APGAR skoru her iki grupta karşılaştırıldı. İstatistiksel analizler SPSS 15 programı kullanılarak yapıldı. Bulgular: Ortalama yaş, vücut kitle indeksi VKI ve gravidite gibi maternal özellikler her iki grupta da benzerdi. 1. Saat maternal serum glukoz seviyesi, IUGR grubunda kontrol grubuna göre istatistiksel olarak anlamlı daha düşük bulundu p=0.012 . Her iki grup için umbilikal arter dopler akımları, doğum sırasındaki gebelik haftası, 5. Dakika APGAR skoru ve yeni doğan yakın bakım ünitesine başvuru oranları arasında istatistiksel olarak anlamlı bir farklılık vardı p

Keywords

• Hipoglisemi,50 gram glukoz testi,intrauterine gelişme gerililiği,gebelik

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