Over torsiyonu tanısında nötrofil/lenfosit oranı ve ortalama trombosit hacminin rolü

Abstract

Amaç Over torsiyonu, sıklıkla tanıda gecikmeye neden olan spesifik olmayan semptomlarla ortaya çıkan jinekolojik acillerden biridir. Over torsiyonunun preoperatif kesin tanısını koymada yeterli klinik, laboratuar veya görüntüleme kriteri yoktur. Bu çalışmanın amacı, over torsiyonu tanısında nötrofil/lenfosit oranının (NLO) ve ortalama trombosit hacmi (MPV) değerinin belirleyici rolünü araştırmaktır. Gereçler ve yöntem Bu retrospektif çalışmaya toplam 198 kadın dahil edilerek, iki çalışma grubu oluşturuldu. Grup 1. abdominal eksplorasyon sonrası over torsiyonu tanısı alan 66 hastadan, kontrol grubu benign unrüptüre over kistleri nedeniyle opere edilen 132 hastadan oluşmaktaydı (Grup 2). Gruplar klinik özellikler ve hematolojik parametrelerine göre karşılaştırıldı Demografik ve klinik özellikler ve preoperatif tam kan sayımı parametreleri tıbbi kayıtlardan elde edildi.. Bulgular Kontrol grubu ile karşılaştırıldığında over torsiyonlu olgularda preoperatif ortalama lökosit, nötrofil ve NLO anlamlı olarak yüksek, MPV anlamlı olarak düşüktü (p <0.001). ROC eğrisi analizi, NLO'nun kesme değerinin% 87,9 duyarlılık ve % 68,2 özgüllük ile 2,68 olduğunu gösterdi. MPV düzeyi için kesme değeri 10,05 olup, duyarlılık ve özgüllük düzeyleri sırasıyla % 56,1 ve % 80,3 olarak bulundu. Sonuç Preoperatif NLR ve MPV, over torsiyonunu diğer akut karın nedenlerinden ayırt etmede yardımcı olabilir. Bu parametreler over torsiyonu tanısında öngörücü bir faktör olarak kullanılabilir.

Keywords

• nötrofil lenfosit oranı
• ortalama trombosit hacmi
• over torsiyonu

The role of neutrophil/lymphocyte ratio and mean platelet volume in diagnosis of ovarian torsion

Abstract

Aim Ovarian torsion is one of the gynecological emergencies that often presents with non-specific symptoms leading to delayed diagnosis. There are no adequate clinical, laboratory or imaging criteria to make a definitive diagnosis of ovarian torsion preoperatively. The aim of this study was to investigate the role of the neutrophil to lymphocyte ratio (NLR) and mean platelet volume (MPV) value in the diagnosis of patients with ovarian torsion. Materials and method A total of 198 women were included in this retrospective study and two study groups were formed. Group 1 consisted of 66 patients diagnosed with ovarian torsion following abdominal exploration and the control group consisted of 132 patients who were operated for benign unruptured ovarian cysts (Group 2). Groups were compared according to clinical characteristics and hematological parameters. Demographic and clinical characteristics and preoperative complete blood count parameters were retrieved from the medical records. Results: Mean leukocyte, neutrophil, and NLR were significantly higher, and MPV was significantly lower in patients with ovarian torsion compared to controls (p<0.001). ROC curve analysis demonstrated that cut-off value of NLR was 2.68 with 87.9 % sensitivity and 68.2 % specificity. The cut-off value for the MPV level was 10.05 fL and, the sensitivity and specificity levels were found to be 56.1 % and 80.3 %, respectively. Conclusion: NLR and MPV may be helpful to preoperatively distinguish ovarian torsion from other causes of acute abdomen. These parameters can be used as a predictive factors in the diagnosis of ovarian torsion.

Keywords

• neutrophil to lymphocyte ratio
• mean platelet volume
• ovarian torsion

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