Müllerian Duct Anomalies

Year 2015, Volume: 12 Issue: 2, 83 - 88, 01.03.2015

Aytekin Tokmak Esma Sarıkaya

Abstract

Developmental abnormalities of the genital tract are one of the most important issues of genital system. This condition is required physical and psychological support, from childhood and adolescence, throughout the whole life of a woman with this anomaly. Müllerian duct anomalies lead to various problems, such as infertility and menstrual disorders, and also a multidisciplinary approach is required to these patients due to abnormalities such as urinary tract abnormalities which can be found in these patients. Therefore, in the evaluation, follow up and treatment of the patients with Müllerian anomalies, physicians with the patients and their families together will create harmony and cooperation is crucial for the success to be achieved. Knowing the embryological development of the genital system is very important for this anomaly to be correctly diagnosed and treated.

Keywords

Müllerian duct anomalies, adolescent, embryology

Mülleryan Kanal Anomalileri

Abstract

Genital kanala ait gelişim anomalileri genital sistemin en önemli sorunlarından birisi olup çocukluk ve adölesan dönemden itibaren tüm yaşam boyunca fiziksel ve psikolojik destek gerektiren bir durumdur. Mülleryan kanal anomalileri menstrüel bozukluklar ve infertilite gibi çeşitli sorunlara yol açmakta ayrıca beraberinde bulunabilen üriner sistem anomalileri gibi durumlar sebebiyle bu hastalara multidisipliner yaklaşım gerekmektedir. Dolayısıyla Mülleryan anomalisi olan hastaların değerlendirilmesinde, takip ve tedavilerinde hekim, hasta ve ailesinin birlikte oluşturacakları uyum ve işbirliği elde edilecek başarı açısından oldukça önemlidir. Bu anomalilerin doğru teşhis ve tedavi edilebilmesi için genital sistemin embriyolojik gelişimini bilmek oldukça önemlidir.

Keywords

Mülleryan kanal anomalileri, adölesan, embriyoloji

References

• Saravelos AH, Cocksedge KA, Li TC. Prevalence and diagnosis of con- genital uterine anomalies in women with reproductive failure: A critical appraisal. Hum Reprod Update. 2008;14:415–29.
• Troiano RN, McCarthy SM. Mullerian duct anomalies: Imaging and clini- cal issues. Radiology. 2004;233:19–34.
• Grimbizis GF, Camus M, Tarlatzis BC, Bontis JN, Devroey P. Clinical imp- lications of uterine malformations and hysteroscopic treatment results. Hum Reprod Update. 2001;7:161–74.
• Golan A, Langer R, Bukovsky I, Caspi E.Congenital anomalies of the Mül- lerian system. Fertil Steril. 1989;51:747-55. Review. Erratum in: Fertil Steril 1994;62:210.
• American Fertility Society The AFS classification of adnexal adhesions, distal tubal occlusion, tubal occlusion secondary to tubal ligation, tubal pregnancies, Mullerian anomalies and intrauterine adhesions. Fertil Ste- ril. 1988;49:944–955
• Folch M, Pigem I, KonjeJC. Müllerian agenesis: etiology, diagnosis, and management. Obstet Gynecol Surv 2000;55:644-9.
• Oppelt P, Renner SP, Brucker S, Strissel PL, Strick R, Oppelt PG, Do- err HG, Schott GE, Hucke J, Wallwiener D, Beckmann MW. The VCUAM (Vagina Cervix Uterus Adnex-associated Malformation) classification: a new classification for genital malformations. Fertil Steril. 2005;84:1493– 1497.
• Grimbizis GF, Gordts S, Di Spiezio Sardo A, Brucker S, De Angelis C, Ger- golet M, Li TC, Tanos V, Brölmann H, Gianaroli L, Campo R. The ESHRE/ ESGE consensus on the classification of female genital tract congenital anomalies. Hum Reprod. 2013;28:2032-44.
• Oppelt PG, Lermann J, Strick R, Dittrich R, Strissel P, Rettig I, Schulze C, Renner SP, Beckmann MW, Brucker S, Rall K, Mueller A. Malforma- tions in a cohort of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome (MRKH).Reprod Biol Endocrinol. 2012;10:57.
• Morcel K, Camborieux L, Guerrier D. Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome. Orphanet J Rare Dis. 2007;2:13.
• RockJA. Surgery for anomalies of the Mullarian ducts.In: Rock JA, Thompson JD, eds. Te Linde’ s operative Gynecology, 8th ed.Philedelp- hia: Lippincott-RavenPublishers; 1997:687-727.
• Reinhold C, Hricak H, Forstner R, Ascher SM, Bret PM, Meyer WR, Se- melka RC. Primary amenorrhea: evaluation with MR imaging. Radiology. 1997;203:383-90.
• Economy KE, Barnewolt C, LauferMR. A comparison of MRI and laparos- copy in detecting pelvic structures in cases of vaginal agenesis. J Pediatr Adolesc Gynecol. 2002;15:101-4.
• Jones HW Jr. Müllerian anomalies. Hum Reprod. 1998;13:789-91.
• Mee-Hwa Lee. Non-surgical Treatment of Vaginal Agenesis Using a Simplified Version of Ingram’s Method Yonsei Med J. 2006; 47: 892– 895.
• Nonsurgical diagnosis and management of vaginal agenesis. Committee on Adolescent Health Care. American College of Obstetrics and Gyneco- logy. Number 274, July 2002.
• Pizzo A, Laganà AS, Sturlese E, Retto G, Retto A, De Dominici R, PuzzoloD. Mayer-rokitansky-kuster-hausersyndrome: embryology, genetics and clinical and surgical treatment. ISRN Obstet Gynecol. 2013;2013:628717.
• Rock JA, Azziz R. Genital anomalies in childhood. Clin Obstet Gynecol. 1987;30:682.
• Rock JA, Jones HW Jr. Vaginal forms for dilatation and/or to maintain vaginal patency. Fertil Steril. 1984;42:187-90.
• Olive DL, Henderson DY. Endometriosis and mullerian anomalies. Obstet Gynecol. 1987;69:412-5.
• Rock JA, Zacur HA, Dlugi AM, Jones HW Jr, TeLinde RW. Pregnancy suc- cess following surgical correction of imperforate hymen and complete transverse vaginal septum. Obstet Gynecol. 1982;59:448-51.
• Markham SM, Parmley TH, Murphy AA, Huggins GR, Rock JA. Cervical agenesis combined with vaginal agenesis diagnosed by magnetic reso- nance imaging. Fertil Steril. 1987;48:143-5
• Rock JA, Schlaff WD, Zacur HA, Jones HW Jr. The clinical manage- ment of congenital absence of the uterine cervix. Int J Gynaecol Obstet. 1984;22:231-5.
• Patton PE. Anatomic uterine defects. Clin Obstet Gynecol 1994;37:705- 21
• Propst AM, Hill JA 3rd. Anatomic factors associated with recurrent preg- nancy loss. Semin Reprod Med. 2000;18:341-50.
• J Lolis DE, Paschopoulos M, Makrydimas G, Zikopoulos K, Sotiriadis A, Paraskevaidis E. Reproductive outcome after strassman metroplasty in women with a bicornuate uterus. Reprod Med. 2005;50:297-301.
• Gell JS. Mülleri ananomalies. Semin Reprod Med. 2003;21:375-88.
• Raga F, Bauset C, Remohi J, Bonilla-Musoles F, Simón C, Pelli- cer A. Reproductive impact of congenital Müllerian anomalies. Hum Reprod. 1997;12:2277-81.
• Lin PC, Bhatnagar KP, Nettleton GS et al. Female genital anomalies affec- ting reproduction. Fertil Steril 2002;78:899–915.
• Goldberg JM, Falcone T. Effect of diethylstilbestrol on reproductive func- tion. Fertil Steril. 1999;72:1-7.