A rare preeclampsia condition: Twin pregnancy with complete type hydatidiform mole and coexisting alive fetus, case report and review of the literature

Year 2020, Volume: 17 Issue: 1, 320 - 322, 31.03.2020

Seyit Ahmet Erol , Filiz Halıcı , Ayşe Kırbaş , Şevki Çelen , Ali Çağlar

Abstract

Twin pregnancy with complete type hydatiform mole and coexistent live fetus (CHMCF) is a rare obstetric condition in the clinic. Management of pregnancy after diagnosis is controversial due to maternal and fetal complications that may couse a dilemma in practice. Although there are papers which supporting the pregnancy termination in the literature, conservative approach has taken over in recent years. Therefore, counseling to the family is important. In this case report, it was aimed to present a case of twin pregnancy that was with complete type hydatiform mole and coexisting alive fetus and to review of the literature.

Keywords

Twin pregnancy, complete hydatiform mole, alive fetus, preeclampsia

Nadir bir preeklampsi nedeni: Komplet tip mol hidatiform ve canlı fetusun birlikte bulunduğu ikiz gebelik vaka sunumu ve literatürün gözden geçirilmesi

Abstract

Komplet tip mol hidatiform ve canlı fetusun birlikte bulunduğu ikiz gebelik klinikte oldukça nadir rastlanılan obstetrik bir durumdur. Tanı sonrası gebeliğin yönetimi oluşabilecek maternal ve fetal komplikasyonlar nedeniyle tartışmalıdır ve pratikte ikilem yaratır. Literatürde gebelik terminasyonunu destekleyen yayınlar bulunmakla birlikte son yıllarda konservatif yaklaşımın ön plana çıktığı yayınlarda mevcuttur. Bu nedenle aileye verilecek danışmanlık önemlidir. Bu vaka sunumunda komplet tip mol hidatiform ve canlı fetusun birlikte bulunduğu, canlı doğumla sonuçlanan bir ikiz gebelik olgusunun sunulması ve literatürün gözden geçirilmesi amaçlanmıştır.

Keywords

İkiz gebelik, komplet hidatiform, canlı fetüs, preeklampsi

References

• 1- Rohilla M, Singh P, Kaur J, Jain V, Gupta N, Prasad GR. Individualistic approach to the management of complete hydatidiform mole with coexisting live fetus. Eur J Obstet Gynecol Reprod Biol. 2015 Aug;191:39-42. doi: 10.1016/j.ejogrb.2015.05.017.
• 2-Vimercati A, de Gennaro AC, Cobuzzi I, Grasso S, Abruzzese M, Fascilla FD, Cormio G, Selvaggi L. Two case of complete hydatidiform mole with coexistent live fetus. J Perinat Med 2013;7(1):1–4.
• 3- Kwon HE, Park EJ, Kim SH, Chae HD, Won HS, Kim CH, Kang BM. A case of twin pregnancy with complete hydatiform mole and coexisting fetus following IVF-ET. J Assist Reprod Genet. 2002;19:144-8
• 4- Matsui H, Sekiya S, Hando T, Wake N, Tomoda Y. Hydatiform mole coexistent with a twin live fetus: a national collaborative study in Japan. Hum Reprod 2000;15:608-11
• 5-Valero F, Macara L, Shaker A. Twin pregnancy with a complete hydatiform mole and coexisting fetus following invitrofertilization. Hum Reprod 1999;14:2905-7
• 6-Büyükkurt S, Kalelioğlu I, Çitil İ, Has R. Twin gestation with a complete mol hydatiform and a normal fetus: a case report Türkiye Klinikleri J Gynecol Obst 2005,15:277-80
• 7-Piura B, Rabinovich A, Hershkovitz R, Maor E, Mazor M. Twin pregnancy with a complete hydatiform mole and surviving co-existent fetus. Arch Gynecol Obstet 2008;278:377-82
• 8- Guven ES, Ozturk N, Deveci S, Hizli D, Kandemir O, Dilbaz S. Partial molar pregnancy and coexisting fetus with diploid karyotype. J Matern Fetal Neonatal Med. 20:175-81,2007
• 9- Wee L, Jauniaux E. Prenatal diagnosis and management of twin pregnancies complicated by a co-existing molar pregnancy. Prenat Diagn 2005;25:772-6
• 10- Sebire NJ, Foskett M, Paradinas FJ, Fisher RA, Francis RJ, Short D, Newlands ES, Seckl MJ. Outcome of twin pregnancies with complete hydatiform mole and healthy co-twin. Lancet 2002;359:2165-6
• 11- Massardier J, Golfier F, Journet D, Frappart L, Zalaquett M, Schott AM, Lenoir VT, Dupuis O, Hajri T, Raudrant D. Twin pregnancy with complete hydatiform mole and coexistent fetus:obstetric alandoncological outcomes in a series of 14 cases. Eur J Obstet Gynecol Reprod Biol 2009;143:84-7
• 12-Niemann I, Sunde L, Petersen LK. Evaluation of the risk of persistent trophoblastic disease after twin pregnancy with diploid hydatidiform mole and coexisting normal fetus. Am J Obstet Gynecol 2007;197(1):45.e1–e5.
• 13- Moini A, Ahmadi F, Eslami B, Zafarani F. Dizygotic twin pregnancy with a complete hydatidiform mole and a coexisting viable fetus. Iran J Radiol 2011;8(4):249–52