BAKTERİYEL VAJİNOZİS RİSKİ VE KONTRASEPSİYON

Year 2020, Volume: 17 Issue: 3, 407 - 411, 30.09.2020

Selçuk Kaplan

https://doi.org/10.38136/jgon.690765

Abstract

Özet
Amaç: Bu çalışmanın amacı, sık görülen vajinal enfeksiyonlardan olan bakteriyel vaginozisin Türkiye’de sık kullanılan iki kontraseptif yöntem olan bakırlı rahim içi araç kullanımı ve kombine oral kontraseptif kullanımı ile ilişkisini ortaya koymaktır.
Gereç ve Yöntem: Bu çalışma 2016-2019 yılları arasında jinekoloji polikliniğimize başvuran hastaların hastanemiz veri tabanına kayıtlı vajinal ve sitolojik örneklerin mikrobiyolojik ve patolojik değerlendirme sonuçları kullanılarak yapılmış, kesitsel bir çalışmadır. Çalışmaya dahil edilen 942 kadın hasta; KOKS kullanan hastalar, Cu- RİA kullanan hastalar ve medikal kontraseptif yöntem kullanmayan hastalar olarak sınıflandırıldı. Mikrobiyoloji kültürlerinde gardnerella vaginalis üreyen ve vajinal sitolojilerinde patolojik olarak BV tanısı konulan hastalar belirlenmiştir. Verilerin analizinde Pearson ki-kare testi ve multinominal lojistik regresyon analizi kullanılmıştır. p<0,05 değeri önemli olarak kabul edilmiştir.
Bulgular: Kontraseptif yöntem olarak Cu-RİA kullanan kadın sayısı 518 (%55), kontraseptif yöntem olarak KOKS kullanan kadın sayısı 238 (%25,3) ve herhangi bir medikal kontraseptif yöntem kullanmayan kadın sayısı 186 (%19,7)’ ydi. Kontraseptif kullanımı ve türü ile vajinal sitoloji arasındaki ilişki değerlendirildiğinde Cu-RİA kullanan grupta BV rastlanma sıklığı istatiksel olarak yüksek bulundu (p<0,001). Sitolojik tanı sonucunu tahmin etmek için kurulan multinominal lojistik regresyon analizinde modele dahil edilen bağımsız değişkenlerden yaş ve Cu-RİA kullanımının modele anlamlı katkı yaptığı görülmüştür (p<0,004 ve p<0,001). Yaş artıkça BV gelişme riski 1,035 kat ve Cu-RİA kullanımı ile BV gelişme riski 2,3 kat artmaktadır.
Sonuç: Cu-RİA kullanımının BV gelişme riskini arttırdığına dair güçlü istatiksel kanıtlar mevcuttur. KOKS kullanımı ile BV gelişme riski arasında ise istatiksel olarak anlamlı ilişki yoktur.
Anahtar Kelimeler: Bakırlı RİA, Oral Kontraseptif, Bakteriyel Vajinozis

Abstract
Aim: The aim of this study is bacterial vaginosis, which is one of the common vaginal infections; to reveal the relationship between copper contraceptive use and combined oral contraceptive use, which are two commonly used contraceptive methods in Turkey.
Materials and Method: This study is a cross-sectional study using the microbiological and pathological evaluation results of vaginal cytological samples of patients who applied to our gynecology outpatient clinic between 2016-2019. Nine hundred fourty two female patients included in the study; patients using combine oral contraceptives were classified as patients using copper intraauterine device and patients not using medical contraceptives. Patients with gardnerella vaginalis reproducing in microbiology cultures and with a diagnosis of BV in their vaginal cytology were identified. Pearson chi-square test and multinominal logistic regression analysis were used in the analysis of the data. p <0.05 value was accepted as important.
Results: In the multinominal logistic regression analysis established to estimate the cytological diagnosis result, age and Cu-IUD use, which are among the independent variables included in the model, significantly contributed to the model (p <0.004 and p <0.001). The risk of BV development increases 2.3 times with the use of Cu-IUD.
Conclusion: There is strong statistical evidence that the use of Cu-IUD increases the risk of developing BV. There is no statistically significant relationship between the use of COC and the risk of developing BV.
Keywords: Copper IUDs, Oral Contraceptives, Bacterial Vaginosis

Keywords

Bakırlı RİA, Oral Kontraseptifler, Bakteriyel Vajinozis

References

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