Research Article
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Geç Preterm Bebeklerin Yenidoğan Dönemi Sorunları

Year 2020, Volume: 17 Issue: 4, 574 - 579, 31.12.2020
https://doi.org/10.38136/jgon.731839

Abstract

Amaç: Erken doğumlar, özellikle gelişmiş ülkelerde perinatal dönemin önemli sorunlarından biridir ve tüm dünyada yenidoğan ölümlerinin önde gelen nedenlerinden biridir. Tüm preterm doğumların %70-75’ini oluşturan geç preterm bebekler, term bebeklere kıyasla kısa ve uzun dönemde artmış oranda birçok morbiditeye sahiptirler. Bu çalışmada hastanemizde doğan geç preterm bebeklerin kısa dönem sonuçlarının değerlendirilmesi amaçlanmıştır. Gereçler ve yöntem: Bu çalışmada 1 Ocak 2019-31 Aralık 2019 tarihleri arasında doğan geç preterm bebeklerin retrospektif olarak yenidoğan dönemi sonuçları incelenmiştir. Bulgular: Çalışmayan 2019 yılında doğan toplam 852 geç preterm bebek alındı. Ortalama gestasyonel hafta 35,3 ± 0,7 haftaydı. Olguların %49,3’ünün hastaneye yatış/sevki gerçekleştirilirken kalan olgular taburcu edildi. En sık hospitalizasyon nedenleri hiperbilirubinemi (%37), solunum sıkıntısı (%35,2) ve sepsis (%27,8) olarak belirlendi. Yatış süresi 10,3 (1-59) gün iken, olguların sadece 6 tanesi izlemde hastaneye tekrar yatırıldı. Çalışmaya alınan olguların 8 tanesi izlemde kaybedildi. Sonuç: Geç preterm doğumlar mümkünse engellenmeli ve yenidoğan döneminde sarılık, solunum sıkıntısı, beslenme intoleransı ve sepsis riski gibi gelişebilecek hastalıklar açısından yakın takip edilmelidir.

References

  • 1Kramer MS, Demissie K, Yang H, Platt RW, Sauve R, Liston R. The Contribution of Mild and Moderate Preterm Birth to Infant Mortality. Fetal and Infant Health Study Group of the Canadian Perinatal Surveillance System. JAMA 2000; 284 (7), 843-9.
  • Uslu S, Zübarioğlu U, Bülbül A. Geç preterm bebeklerde erken dönem solunum problemleri. Ş.E.E.A.H. Tıp Bülteni 2017; 51(3): 184-90.
  • Bassil KL, Shah PS, Shah V, Ye XY, Lee SK, Jefferies AL and the Canadian Neonatal Network. Impact of Late Preterm and Early Term Infants on Canadian Neonatal Intensive Care Units. Am J Perinatol 2014; 31: 269-78.
  • Jefferies AL, Lyons ER, Shah PS, Shah V. Impact of Late Preterm Birth on Neonatal Intensive Care Resources in a Tertiary Perinatal Center. Am J Perinatol 2013; 30: 573-8.
  • Helvacı H, Bozgül A, Onursal Helvacı Y, Tatlı Güneş B, Orbatu D, Güneş S. Geç preterm bebeklerde Yenidoğan Yoğun Bakım Ünitesi’ne yatışı gerektiren erken neonatal sorunlar. İzmir Dr. Behçet Uz Dergis 2014; 4(1): 44-50.
  • Loftin RW, Habli M, Synder CC, Cormieer CM, Lewis DF, DeFranco EA. Late preterm birth. Rev Obstet Gynecol 2010; 3: 10-9.
  • Celik İH, Demirel G, Canpolat FE, Dilmen U. A common problem for neonatal intensive care units: late preterm infants, a prospective study with term controls in a large perinatal center. J Matern Fetal Neonatal Med. 2013; 26(5): 459-62. doi: 10.3109/14767058.2012.735994. Epub 2012 Oct 31.
  • Weiner GM, Zaichkin J, Kattwinkel J, editors. Textbook of Neonatal Resuscitation. 7th ed. Elk Grove Village, IL: American Academy of Pediatrics and American Heart Association, 2016.
  • Akisu M, Kumral A, Canpolat FE. Turkish Neonatal Society Guideline on neonatal encephalopathy. Turk Pediatri Ars 2018; 53: S32-S44.
  • Çoban A, Kaynak Türkmen M, Gürsoy T. Turkish Neonatal Society Guideline to the approach, follow-up, and treatment of neonatal jaundice. Turk Pediatri Arş 2018; 53(1): 172-9. DOI: 10.5152/TurkPediatriArs.2018.01816
  • American Academy of Pediatrics Subcommittee on Hyperbilirubinemia. Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics. 2004 Jul; 114(1): 297-316. doi: 10.1542/peds.114.1.297.
  • Committee on Fetus and Newborn, Adamkin DH. Postnatal glucose homeostasis in late-preterm and term infants. Pediatrics. 2011;127 (3):575–9. doi:10.1542/peds.2010-3851
  • Papile LA, Burstein J, Burstein R, Koffler H. Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weight less than 1500 gm. J Pediatr 1978; 92: 529-34.
  • Raju TNK. The “Late Preterm” Birth-Ten Years Later. Pediatrics 2017; 139(3): e20163331.
  • Hamilton BE, Martin JA, Osterman MJ, Curtin SC, Matthews TJ. Births: final data for 2014. Natl Vital Stat Rep. 2015; 64(12): 1-64.
  • Khowaja WH, Leghari A, Hussain A, Ariff S, Khan IA. Frequency and Early Complications of Late Preterm İnfants: A Descriptive Analysis from Two Secondary-Care Hospitals of Karachi. Cureus. 2019 Sep 28;11(9):e5789. doi: 10.7759/cureus.5789.
  • Kultursay N, Koroglu OA, Uygur O, Terek D, Tanriverdi S, Akisu M, et al. Improved neonatal prognosis following restriction in the number of transferred embryos in assisted reproduction - single center yearly comparison from Turkey. Clin Exp Obstet Gynecol. 2015; 42(4): 442-7.
  • Melamed N, Klinger G, Tenenbaum-Gavish K, Herscovici T, Linder N, Hod M, et al. Short-term neonatal outcome in low-risk, spontaneous, singleton, late preterm deliveries. Obstet Gynecol. 2009 Aug;114 (2 Pt 1): 253-60. doi: 10.1097/AOG.0b013e3181af6931.
  • Leone A, Ersfeld P, Adams M, Schiffer PM, Bucher HU, Arlettaz R. Neonatal morbidity in singleton late preterm infants compared with full-term infants. Acta Paediatr. 2012;101(1):e6–e10. doi:10.1111/j.1651-2227.2011.02459.x
  • Ma X, Huang C, Lou S, Lv Q, Su W, Tan J, et al. The clinical outcomes of late preterm infants: a multi-center survey of Zhejiang, China. J Perinat Med. 2009;37(6):695–9. doi:10.1515/JPM.2009.130
  • Tsai ML, Lien R, Chiang MC, Hsu JF, Fu RH, Chu SM, et al. Prevalence and morbidity of late preterm infants: current status in a medical center of Northern Taiwan. Pediatr Neonatol. 2012;53(3):171–177. doi:10.1016/j.pedneo.2012.04.003
  • Ortigosa Rocha C, Bittar RE, Zugaib M. Neonatal outcomes of late-preterm birth associated or not with intrauterine growth restriction. Obstet Gynecol Int. 2010;2010:231842. doi:10.1155/2010/231842
  • Sarici SU, Serdar MA, Korkmaz A, Erdem G, Oran O, Tekinalp G, ve ark. Incidence, course, and prediction of hyperbilirubinemia in near-term and term newborns. Pediatrics. 2004;113(4):775–780. doi:10.1542/peds.113.4.775
  • Mally PV, Hendricks-Muñoz KD, Bailey S. Incidence and etiology of late preterm admissions to the neonatal intensive care unit and its associated respiratory morbidities when compared to term infants. Am J Perinatol. 2013;30(5):425–431. doi:10.1055/s-0032-1326989
  • Jobe AH. The Respiratory System, Part I: Lung development and maturation. In: Martin RJ, Fanaroff AA, Walsch MC,eds. Fanaroff and Martin’s Neonatal-Perinatal Medicine. 8th ed. Philadelphia, PA: Mosby Elsevier; 2006: 585-97.
  • Sürmeli-Onay O, Korkmaz A, Yiğit S, Yurdakök M. Surfactant therapy in late preterm infants: respiratory distress synd rome and beyond. Turk J Pediatr 2012;54:239-46.
  • Clapp DW. Developmental regulation of the immune system. Semin Perinatol 2006; 30:24-7.
  • Favrais G, Saliba E. Neurodevelopmental outcome of late-preterm infants: Literature review. Arch Pediatr. 2019;26(8):492‐496. doi:10.1016/j.arcped.2019.10.005
  • Morse SB, Zheng H, Tang Y, Roth J. Early school-age outcomes of late preterm infants. Pediatrics. 2009;123(4):e622‐e629. doi:10.1542/peds.2008-1405
Year 2020, Volume: 17 Issue: 4, 574 - 579, 31.12.2020
https://doi.org/10.38136/jgon.731839

Abstract

References

  • 1Kramer MS, Demissie K, Yang H, Platt RW, Sauve R, Liston R. The Contribution of Mild and Moderate Preterm Birth to Infant Mortality. Fetal and Infant Health Study Group of the Canadian Perinatal Surveillance System. JAMA 2000; 284 (7), 843-9.
  • Uslu S, Zübarioğlu U, Bülbül A. Geç preterm bebeklerde erken dönem solunum problemleri. Ş.E.E.A.H. Tıp Bülteni 2017; 51(3): 184-90.
  • Bassil KL, Shah PS, Shah V, Ye XY, Lee SK, Jefferies AL and the Canadian Neonatal Network. Impact of Late Preterm and Early Term Infants on Canadian Neonatal Intensive Care Units. Am J Perinatol 2014; 31: 269-78.
  • Jefferies AL, Lyons ER, Shah PS, Shah V. Impact of Late Preterm Birth on Neonatal Intensive Care Resources in a Tertiary Perinatal Center. Am J Perinatol 2013; 30: 573-8.
  • Helvacı H, Bozgül A, Onursal Helvacı Y, Tatlı Güneş B, Orbatu D, Güneş S. Geç preterm bebeklerde Yenidoğan Yoğun Bakım Ünitesi’ne yatışı gerektiren erken neonatal sorunlar. İzmir Dr. Behçet Uz Dergis 2014; 4(1): 44-50.
  • Loftin RW, Habli M, Synder CC, Cormieer CM, Lewis DF, DeFranco EA. Late preterm birth. Rev Obstet Gynecol 2010; 3: 10-9.
  • Celik İH, Demirel G, Canpolat FE, Dilmen U. A common problem for neonatal intensive care units: late preterm infants, a prospective study with term controls in a large perinatal center. J Matern Fetal Neonatal Med. 2013; 26(5): 459-62. doi: 10.3109/14767058.2012.735994. Epub 2012 Oct 31.
  • Weiner GM, Zaichkin J, Kattwinkel J, editors. Textbook of Neonatal Resuscitation. 7th ed. Elk Grove Village, IL: American Academy of Pediatrics and American Heart Association, 2016.
  • Akisu M, Kumral A, Canpolat FE. Turkish Neonatal Society Guideline on neonatal encephalopathy. Turk Pediatri Ars 2018; 53: S32-S44.
  • Çoban A, Kaynak Türkmen M, Gürsoy T. Turkish Neonatal Society Guideline to the approach, follow-up, and treatment of neonatal jaundice. Turk Pediatri Arş 2018; 53(1): 172-9. DOI: 10.5152/TurkPediatriArs.2018.01816
  • American Academy of Pediatrics Subcommittee on Hyperbilirubinemia. Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics. 2004 Jul; 114(1): 297-316. doi: 10.1542/peds.114.1.297.
  • Committee on Fetus and Newborn, Adamkin DH. Postnatal glucose homeostasis in late-preterm and term infants. Pediatrics. 2011;127 (3):575–9. doi:10.1542/peds.2010-3851
  • Papile LA, Burstein J, Burstein R, Koffler H. Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weight less than 1500 gm. J Pediatr 1978; 92: 529-34.
  • Raju TNK. The “Late Preterm” Birth-Ten Years Later. Pediatrics 2017; 139(3): e20163331.
  • Hamilton BE, Martin JA, Osterman MJ, Curtin SC, Matthews TJ. Births: final data for 2014. Natl Vital Stat Rep. 2015; 64(12): 1-64.
  • Khowaja WH, Leghari A, Hussain A, Ariff S, Khan IA. Frequency and Early Complications of Late Preterm İnfants: A Descriptive Analysis from Two Secondary-Care Hospitals of Karachi. Cureus. 2019 Sep 28;11(9):e5789. doi: 10.7759/cureus.5789.
  • Kultursay N, Koroglu OA, Uygur O, Terek D, Tanriverdi S, Akisu M, et al. Improved neonatal prognosis following restriction in the number of transferred embryos in assisted reproduction - single center yearly comparison from Turkey. Clin Exp Obstet Gynecol. 2015; 42(4): 442-7.
  • Melamed N, Klinger G, Tenenbaum-Gavish K, Herscovici T, Linder N, Hod M, et al. Short-term neonatal outcome in low-risk, spontaneous, singleton, late preterm deliveries. Obstet Gynecol. 2009 Aug;114 (2 Pt 1): 253-60. doi: 10.1097/AOG.0b013e3181af6931.
  • Leone A, Ersfeld P, Adams M, Schiffer PM, Bucher HU, Arlettaz R. Neonatal morbidity in singleton late preterm infants compared with full-term infants. Acta Paediatr. 2012;101(1):e6–e10. doi:10.1111/j.1651-2227.2011.02459.x
  • Ma X, Huang C, Lou S, Lv Q, Su W, Tan J, et al. The clinical outcomes of late preterm infants: a multi-center survey of Zhejiang, China. J Perinat Med. 2009;37(6):695–9. doi:10.1515/JPM.2009.130
  • Tsai ML, Lien R, Chiang MC, Hsu JF, Fu RH, Chu SM, et al. Prevalence and morbidity of late preterm infants: current status in a medical center of Northern Taiwan. Pediatr Neonatol. 2012;53(3):171–177. doi:10.1016/j.pedneo.2012.04.003
  • Ortigosa Rocha C, Bittar RE, Zugaib M. Neonatal outcomes of late-preterm birth associated or not with intrauterine growth restriction. Obstet Gynecol Int. 2010;2010:231842. doi:10.1155/2010/231842
  • Sarici SU, Serdar MA, Korkmaz A, Erdem G, Oran O, Tekinalp G, ve ark. Incidence, course, and prediction of hyperbilirubinemia in near-term and term newborns. Pediatrics. 2004;113(4):775–780. doi:10.1542/peds.113.4.775
  • Mally PV, Hendricks-Muñoz KD, Bailey S. Incidence and etiology of late preterm admissions to the neonatal intensive care unit and its associated respiratory morbidities when compared to term infants. Am J Perinatol. 2013;30(5):425–431. doi:10.1055/s-0032-1326989
  • Jobe AH. The Respiratory System, Part I: Lung development and maturation. In: Martin RJ, Fanaroff AA, Walsch MC,eds. Fanaroff and Martin’s Neonatal-Perinatal Medicine. 8th ed. Philadelphia, PA: Mosby Elsevier; 2006: 585-97.
  • Sürmeli-Onay O, Korkmaz A, Yiğit S, Yurdakök M. Surfactant therapy in late preterm infants: respiratory distress synd rome and beyond. Turk J Pediatr 2012;54:239-46.
  • Clapp DW. Developmental regulation of the immune system. Semin Perinatol 2006; 30:24-7.
  • Favrais G, Saliba E. Neurodevelopmental outcome of late-preterm infants: Literature review. Arch Pediatr. 2019;26(8):492‐496. doi:10.1016/j.arcped.2019.10.005
  • Morse SB, Zheng H, Tang Y, Roth J. Early school-age outcomes of late preterm infants. Pediatrics. 2009;123(4):e622‐e629. doi:10.1542/peds.2008-1405
There are 29 citations in total.

Details

Primary Language Turkish
Subjects Paediatrics
Journal Section Research Articles
Authors

Özgün Uygur 0000-0002-7580-915X

Deniz Gönülal This is me 0000-0002-9816-0613

Melek Akar 0000-0002-0178-2011

Defne Engür This is me 0000-0003-0405-085X

Mehmet Yekta Öncel 0000-0003-0760-0773

Publication Date December 31, 2020
Submission Date May 4, 2020
Acceptance Date July 29, 2020
Published in Issue Year 2020 Volume: 17 Issue: 4

Cite

Vancouver Uygur Ö, Gönülal D, Akar M, Engür D, Öncel MY. Geç Preterm Bebeklerin Yenidoğan Dönemi Sorunları. JGON. 2020;17(4):574-9.