Case Report
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Year 2021, Volume: 4 Issue: 2, 240 - 242, 28.03.2021
https://doi.org/10.32322/jhsm.867371

Abstract

References

  • World Health Organization. Director-General's remarks at the media briefing on 2019-nCoV on 11 February 2020. http://www.who.int/dg/speeches/detail/who-director-general-s-remarks-at-the-media-briefing-on-2019-ncov-on-11-february-2020 (Accessed on October 12, 2020).
  • Lu R, Zhao X, Li J, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 2020; 395: 565–74.
  • Hamming I, Timens W, Bulthuis ML, Lely AT, Navis G, van Goor H. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J Pathol 2004; 203: 631–7.
  • Guan W-J, Ni Z-Y, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020. doi:10.1056/NEJMoa2002032.
  • Hopkins C, Kumar N (2020) Loss of sense of smell as a marker of COVID-19 infection. ENTUK (cited 2020 November 12); Available from https://www.entuk.org/sites/default/files/files/Loss%20of%20sense%20of%20smell%20as%20marker%20of%20COVID.pdf
  • Mao L. Neurological manifestations of hospitalized patients with COVID-19 in Wuhan. China: retrospective case series study. 2020.
  • Alay H, Gözgeç E. Cerebral ınfarction in an elderly patient with coronavirus disease. Rev Soc Bras Med 2020; 53: e20200307.
  • Smith HS, Busracamwongs A. Management of hiccups in the palliative care population. Am J Hosp Palliat Care. 2003; 20: 149.
  • Souadjian JV, Cain JC. Intractable hiccup. Etiologic factors in 220 cases. Postgrad Med 1968; 43: 72.
  • Prince G, Sergel M. Persistent hiccups as an atypical presenting complaint of COVID-19. Am J Emerg Med 2020; 38: 1546.e5-1546.e6.

Can persistent hiccups be a progression marker in COVID-19?

Year 2021, Volume: 4 Issue: 2, 240 - 242, 28.03.2021
https://doi.org/10.32322/jhsm.867371

Abstract

Hiccup is a reflex action that may rarely be intractable. A 55-year-old man diagnosed with COVID-19 was hospitalized to our clinic with body temperature elevation, weakness, and headache persisting for the previous three days. Persistent hiccups were present during follow-up, and progression was observed at pulmonary tomography with an increase in the numbers and dimensions of focal ground glass areas. Lymphocyte count was 920/µL, platelet count 138X103/µL, sedimentation rate 6 mm/h, ferritin 1256 ng/mL, C-reactive protein 16.8 mg/L, aspartate aminotransferase 43 U/L, alanine aminotransferase 67 U/L, and lactate dehydrogenase 326 U/L. Other potential causes of persistent hiccups were excluded. COVID-19 immune plasma and remdesivir therapy were initiated. The hiccups resolved two days after treatment, and the patient was discharged on the 11th day of follow-up. Persistent hiccups should be remembered among the symptoms that may appear during the clinical progression of COVID-19.

References

  • World Health Organization. Director-General's remarks at the media briefing on 2019-nCoV on 11 February 2020. http://www.who.int/dg/speeches/detail/who-director-general-s-remarks-at-the-media-briefing-on-2019-ncov-on-11-february-2020 (Accessed on October 12, 2020).
  • Lu R, Zhao X, Li J, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 2020; 395: 565–74.
  • Hamming I, Timens W, Bulthuis ML, Lely AT, Navis G, van Goor H. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J Pathol 2004; 203: 631–7.
  • Guan W-J, Ni Z-Y, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020. doi:10.1056/NEJMoa2002032.
  • Hopkins C, Kumar N (2020) Loss of sense of smell as a marker of COVID-19 infection. ENTUK (cited 2020 November 12); Available from https://www.entuk.org/sites/default/files/files/Loss%20of%20sense%20of%20smell%20as%20marker%20of%20COVID.pdf
  • Mao L. Neurological manifestations of hospitalized patients with COVID-19 in Wuhan. China: retrospective case series study. 2020.
  • Alay H, Gözgeç E. Cerebral ınfarction in an elderly patient with coronavirus disease. Rev Soc Bras Med 2020; 53: e20200307.
  • Smith HS, Busracamwongs A. Management of hiccups in the palliative care population. Am J Hosp Palliat Care. 2003; 20: 149.
  • Souadjian JV, Cain JC. Intractable hiccup. Etiologic factors in 220 cases. Postgrad Med 1968; 43: 72.
  • Prince G, Sergel M. Persistent hiccups as an atypical presenting complaint of COVID-19. Am J Emerg Med 2020; 38: 1546.e5-1546.e6.
There are 10 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Report
Authors

Handan Alay 0000-0002-4406-014X

Nazım Doğan This is me 0000-0001-6706-5085

Zülal Özkurt 0000-0001-5554-8768

Nuray Bilge 0000-0002-9328-1678

Fatma Kesmez Can 0000-0001-8085-7589

Ömer Araz 0000-0003-1758-0542

Publication Date March 28, 2021
Published in Issue Year 2021 Volume: 4 Issue: 2

Cite

AMA Alay H, Doğan N, Özkurt Z, Bilge N, Kesmez Can F, Araz Ö. Can persistent hiccups be a progression marker in COVID-19?. J Health Sci Med / JHSM. March 2021;4(2):240-242. doi:10.32322/jhsm.867371

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