Emergence of multidrug resistant uropathogenic Escherichia coli (UPEC) strains isolated from a hospital in Bangladesh

Abstract

Background: Multidrug Resistant Uropathogenic Escherichia coli (UPEC) is becoming a global concern. Therefore, the purpose of the present study was to see the status of multidrug resistant UPEC strains.

Materials and Methods: This retrospective study was conducted at a private Hospital in Dhaka city from July 2013 to December 2013 for a period of six months. All the patients who were attended in the OPD or admitted in the IPD of the hospital presenting the clinical features of UTI at any age with both sexes were included as the study population. Patients without significant pus cell within urine, patients under antibiotic therapy or incomplete data were excluded from this study. E. coli was isolated and identified by standard methods and antibiotic sensitivity testing was performed by disk diffusion method.

Results: A total number of 57 UPEC were isolated of which 9 isolates were isolated from male and 48 isolates were from female. Resistant to four groups, five groups, six groups and seven groups of drugs were found in 17.5% (95% CI 7.64 to 27.36%), 14.0% (95% CI 4.99 to 23.01%), 10.5% (95% CI 2.54 to 18.46%) and 8.8% (95% CI 1.45 to 16.15%) uropathogenic E. coli respectively. The total number of MDR UPEC was 92.9% (95% CI 86.23 to 99.57%). In a total multidrug resistant uropathogenic E. coli were found in 92.9% isolates.

Conclusion: In conclusion multidrug resistant uropathogenic E. coli is found in a very high rate.

Keywords

• Multidrug resistant,uropathogenic,Escherichia coli,emergence,UPEC

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