Prevalence of vulvovaginal candidiasis and treatment with isoconazol nitrate

Abstract

Background: Vulvovaginal candidiasis (VVC) was an infection caused by Candida species that affects millions of women every year. Candida albicans was the main cause of VVC. The development of VVC was usually attributed to the disturbance of the balance between Candida vaginal colonization and host environment by physiological or non-physiological changes. Several host-related and behavioral risk factors have been proposed as predisposing factors for VVC. Host-related factors include pregnancy, hormone replacement, uncontrolled diabetes, immunosuppression, antibiotics, glucocorticoids use and genetic predispositions. Behavioral risk factors include use of oral contraceptives, intrauterine device, spermicides and condoms and some habits of hygiene, clothing and sexual practices.

Materials and Methods: A total of 448 women with vaginal infection were studied retrospectively. Yeasts were isolated from the samples of 140 patients with vulvovaginal candidiasis. Routine diagnostic methods were used. A total of 113 patients were included to our treatment protocol.

Results and Conclusions: This study provides information about the current state of epidemiology and microbiology of VVC, as well as quite effective treatment of symptomatic and uncomplicated VVC with confirmed by laboratory results with isoconazole nitrate (a single dose of topical creams or vaginal ovules). We believe that all of them, as well as partner co-treatment and perineal hygiene increase the our success.

Keywords

• Vulvovaginal candidiasis,C. albicans,Isoconazole nitrate

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