Prevalence of vulvovaginal candidiasis and treatment with isoconazol nitrate

Year 2018, , 8 - 14, 30.03.2018

Türkan Toka Özer

https://doi.org/10.5455/jicm.2.20160425

Abstract

Background:
Vulvovaginal candidiasis (VVC) was an infection caused by Candida species that
affects millions of women every year. Candida
albicans was the main cause of VVC. The development of VVC was usually
attributed to the disturbance of the balance between Candida vaginal
colonization and host environment by physiological or non-physiological
changes. Several host-related and behavioral risk factors have been proposed as
predisposing factors for VVC. Host-related factors include pregnancy, hormone
replacement, uncontrolled diabetes, immunosuppression, antibiotics,
glucocorticoids use and genetic predispositions. Behavioral risk factors
include use of oral contraceptives, intrauterine device, spermicides and
condoms and some habits of hygiene, clothing and sexual practices.

Materials and Methods: A total of 448 women with vaginal infection were studied
retrospectively. Yeasts were isolated from the samples of 140 patients with
vulvovaginal candidiasis. Routine diagnostic methods were used. A total of 113
patients were included to our treatment protocol.

Results and Conclusions: This study provides information about the current state of
epidemiology and microbiology of VVC, as well as quite effective treatment of
symptomatic and uncomplicated VVC with confirmed by laboratory results with
isoconazole nitrate (a single dose of topical creams or vaginal ovules). We
believe that all of them, as well as partner co-treatment and perineal hygiene
increase the our success.

Keywords

Vulvovaginal candidiasis, C. albicans, Isoconazole nitrate

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