Autoimmune extraintestinal manifestations of Helicobacter pylori infection: A bundle of conflicts

Year 2018, Most Accessed Articles, 22 - 30, 05.06.2018

Erkan Yula , Fatih Köksal

https://doi.org/10.5455/jicm.10.20160627

Abstract

It has been well-known that several microorganisms
that have an effect on particular areas of the body might additionally have
systemic sequelae. In the last ten years, various studies have been performed
on the relationship between Helicobacter
pylori infection and a variety of extra digestive illnesses including immunological,
hematological, neurological disorders and different pathologies. It has been
recommended that complicated interactions between bacterial and host genetic
factors, as well as environmental factors, play considerable roles in
determining different clinical outcomes. 
Although, there are conflicting and controversy data in some diseases,
in the light of literature, it is currently accepted; that the presence or
absence of H. pylori infection might
influence the chance of developing of many autoimmune diseases. Treatment of H. pylori infection has been reported to
be effective in some diseases like Schoenlein-Henoch purpura, ITP, psoriasis
and chronic autoimmune urticaria. This review focuses the possible role of H. pylori infections in various autoimmune
diseases taking into account the recent literature.

Keywords

Helicobacter pylori, extraintestinal manifestations, autoimmune diseases

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