Background: The objective of this retrospective study was to evaluate healthcare-related Candida infections and factors related mortality.
Materials and Methods: Patients who were followed-up in the Medical intensive care unit (ICU) between 2015 and 2018 were retrospectively evaluated. Data were obtained by active surveillance method based on patient and laboratory. Statistical analysis of the data was performed using the SPSS 22 package program. The number, percentage, mean ± standard deviation and chi-square (χ²) test were used to analyze the distribution of the data obtained. p <0.05 was considered statistically significant.
Results: Fifty-nine (5.8%) of the 1018 patients who were followed up and treated in ICU developed Candida infection. The mean age was 73.9 ± 11.5. 39 patients (66.1%) with urinary catheter-related urinary tract infection, 12 (20.3%) patients with Laboratory Proven Blood Circulation Infection, 6 (10.2%) patients Abscess / soft tissue infection and 2 (3.4%) patients were diagnosed as Central Venous Catheter-Associated Blood Stream Infection. 36 (61%) of Candida species isolated from cultures were C.albicans, 8 (13.6%) were C. parapsilosis, 6 (10.2%) were C.glabrata, 6 (10.2%) were C.. tropicalis, 1 (1.7%) in C. Crusei and 2 (3.3%) were not identified species. 31 (52.5%) of the patients died. Total parenteral nutrition (P: 0.026) and mechanical ventilation (P: 0.004) were statistically significant. There was no statistically significant difference between candida species and mortality (p = 0.086).
Conclusions: Candida infections in ICUs are important causes of mortality. A good description of mortality related factors in Candida infections may lead to a decrease in mortality.
intensive care unit, Candida infection, mortality related factors