Hypericum L. Cinsine Ait Bazı Türlerin Uçucu Yağlarının Antibakteriyel Etkisi

Abstract

Bitkilerden elde edilen biyolojik aktif bileşenlerin incelenmesi son zamanlarda en çok araştırılan konular arasındadır. Türkiye florasının çok zengin bir yapıya sahip olması, bu coğrafyada yetişen bitkilerin araştırılmasının önemli olduğunu göstermektedir. Bu çalışmada, kimyasal bileşen olarak eski ve yaygın bir kullanım alanına sahip olan aynı zamanda önemli bir tıbbi bitki olan Hypericum cinsine ait 3 taksondan elde edilen uçucu yağlar antibakteriyel etkileri yönüyle araştırılmıştır. Hypericum spectabile Jaub. & Spach (endemik tür), H. scabrum L., H. venustum Fenzl. türlerinin uçucu yağları distilasyon yöntemi kullanılarak elde edilmiştir. Elde edilen bu yağların antibakteriyel etkileri, in vitro olarak birçok ilaca direnç gösterdiği bilinen; Enterobacter aerogenes (ATCC 13048), Enterococcus faecalis (ATCC 29212), Salmonella enteritidis (ATCC 13075), Staphylococcus aureus subsp. aureus (ATCC 25923), Escherichia coli (ATCC 25922) ve Serratia marcescens (ATCC 13880) patojen bakterileri kullanılarak araştırılmıştır. Türlerin farklı uçucu yağları, çeşitli mikroorganizmalara karşı antibakteriyel aktivite için oyuk agar testi kullanılarak analiz edilmiştir. Tüm uçucu yağların test edilen tüm patojen strainlerine karşı değişen oranlarda (4,80±0,87-27,73±1,27 mm) aktivite gösterdiği gözlenmiştir. Bu türler, literatürde antibakteriyel aktivite açısından yeni değerlendirilen türler arasında gösterilebilir.

Keywords

• endemik
• hypericum
• uçucu yağ
• antibakteriyel

Antibacterial Effect of Essential Oil Components of Some Species Belonging to the Genus Hypericum L.

Abstract

Examination of biologically active compounds obtained from plants is among the most researched subjects recently. The fact that the flora of Turkey has a very rich structure shows that it is important to research the plants that grow in this geography. In this study, essential oils obtained from 3 taxa of Hypericum genus, which has an old and widespread use as a chemical component and an important medicinal plant, were investigated in terms of their antibacterial effects. Hypericum spectabile Jaub. & Spach (endemic species), Hypericum scabrum L., Hypericum venustum Fenzl. the essential oils of the species were obtained by using the distillation method. The antibacterial effects of these obtained oils are known to be resistant to many drugs in vitro; Enterobacter aerogenes (ATCC 13048), Enterococcus faecalis (ATCC 29212), Salmonella enteritidis (ATCC 13075), Staphylococcus aureus subsp. aureus (ATCC 25923), Escherichia coli (ATCC 25922) and Serratia marcescens (ATCC 13880) pathogenic bacteria. Different extraction extracts of the species were analyzed using the well agar test for antibacterial activity against various microorganisms. It was observed that all extracts showed varying rates (4.80±0.87-27.73±1.27 mm) activity against all tested pathogen strains. These species can be shown among the newly evaluated species in the literature in terms of antibacterial activity.

Keywords

• endemic
• hypericum
• essential oil
• antibacterial

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