One-Pot Synthesis of Substituted Phthalazine-5,10-dione Derivatives in the Presence of Triflate Catalyst

Year 2019, , 468 - 478, 01.03.2019

Kadir Turhan

https://doi.org/10.21597/jist.433331

Cited By: 3

Abstract

In
this study, substituted 1H-pyrazolo[1,2-b]phthalazine-5,10-diones which are
considered that may possess biological activity have been obtained via one-pot
multi-component cyclocondensation reaction of phthalhydrazide, aromatic
aldehydes and malononitrile catalyzed in the presence of Cu(OTf)₂ in
very good yields and short times. The structures of all these synthesized
compounds (4a-f) have been determined and characterized by infrared, nuclear
magnetic resonance, mass spectral data, and elemental analysis.

Keywords

Phthalazinedione, triflate, one-pot, multicomponent, green chemistry

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