Synthesis of Novel 3-Oxobutanohydrazide Derivatives in the Presence of Cerium Ammonium Nitrate

Year 2022, Volume: 12 Issue: 4, 2364 - 2374, 01.12.2022

Furgan Aslanoğlu

https://doi.org/10.21597/jist.1174550

Abstract

In this study, a new synthetic method was developed for new 3-oxobutanohydrazide derivatives. This synthetic method consists of two steps. In the first step, aldehyde phenyl hydrazone derivatives were synthesized. Then, these compounds were reacted with 2,2,6-trimethyl-4H-1,3-dioxin-4-one (TMD) compound in the presence of the catalytic amount of cerium ammonium nitrate and 3-oxobutanohydrazide derivatives, which are new target molecules, were synthesized. The structures of the synthesized 3-oxobutanohyidrazide derivatives were characterized by 1H-NMR and 13C-NMR.

Keywords

3-Oxobutanohydrazide, serium ammonium nitrate, acetylketene

Seryum Amonyum Nitrat Varlığında Yeni 3-Oksobutanohidrazid Türevlerinin Sentezi

Abstract

Bu çalışmada, yeni 3-oksobutanohidrazid türevleri için yeni bir sentetik yöntem geliştirilmiştir. Bu sentetik yöntem iki adımdan oluşmaktadır. İlk aşamada aldehit fenil hidrazon türevleri sentezlendi. Daha sonra, bu bileşikler 2,2,6-trimetil-4H-1,3-dioksin-4-on (TMD) bileşiği ile katalitik miktarda seryum amonyum nitrat varlığında reaksiyona sokularak hedef moleküller olan 3-okzobutanohidrazit türevleri sentezlendi. Sentezlenen 3-oksobutanohidrazid türevlerinin yapıları 1H-NMR ve 13C-NMR ile karakterize edildi.

Keywords

3-Oksobutanohidrazid, seryum amonyum nitrat, asetil keten

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