NSTEMI'da Erken Evrede HALP Skorunun Öngörü Değeri

Year 2024, , 12 - 16, 11.03.2024

Göknur Yıldız , Fatih Alper Ayyıldız , Özge Turgay Yıldırım

https://doi.org/10.36516/jocass.1396148

Abstract

Giriş: Pek çok inflamatuar belirteç, koroner arter hastalığının ciddiyetiyle ve kötü kardiyovasküler sonuçlarla ilişkilidir. Hemoglobin, albumin, lenfosit ve platelet (HALP) skoru inflamasyon ve beslenme durumunun bir göstergesidir. Bu çalışmada ST elevasyonu olmayan miyokard enfarktüslü (NSTEMI) hastalarda HALP skorunun uygulanabilirliğini değerlendirmeyi amaçladık.
Gereç ve Yöntemler: Bu çalışma retrospektif kohort çalışması olarak tasarlandı. Akut koroner sendrom tanısı alan 18 yaş üstü hastalar hastane kayıtlarından geriye dönük olarak tarandı. Çalışma grupları koroner anjiyografi sonuçlarına göre oluşturuldu. Hastaların yaş, cinsiyet gibi demografik verileri, tam kan sayımı, albümin düzeyleri, troponin düzeyleri ve HALP skorları incelenerek gruplar arası karşılaştırmalar yapıldı.
Bulgular: Çalışmaya 201 hasta dahil edilmiş olup veriler hastane kayıtlarından retrospektif olarak elde edilmiştir. ST elevasyonlu miyokard enfarktüsü (STEMI) nedeniyle 79 hasta çalışma dışı bırakıldı. Araştırmanın evreni iki grup altında toplanmıştır; NSTEMI grubu (n=66) ve normal koroner arter (NKA) grubu (n=56). NSTEMI grubunun yaş ortalaması 62,3 ± 11,8 olup %71,2'si (n=47) erkekti. NKA grubunun yaş ortalaması 51,8 ± 9,2 olup %30,3'ü (n=17) erkekti. NSTEMI ve NKA grupları arasında yaş ve cinsiyet açısından istatistiksel olarak anlamlı fark saptandı (p<0,05). HALP skoru NSTEMI grubunda NKA grubuna göre istatistiksel olarak daha yüksek saptandı (p<0,001). Yaş ve HALP skoru NSTEMI hastaları üzerinde açıklayıcı güce sahip olarak saptandı (sırasıyla p=0,001 ve p=0,022).
Sonuç: HALP skoru klinik uygulamada kolay uygulanabilir ve ucuz bir yöntem olarak NSTEMI hastalarının erken tanısına katkı sağlayabilecek bir yöntem olarak kullanılabilir.

Keywords

NSTEMI, Acil Servis, HALP Skoru

Predictive Value of HALP Score in The Early Stage of NSTEMI

Abstract

Introduction: Several inflammatory markers are associated with coronary artery disease severity and worse cardiovascular outcomes. The haemoglobin, albumin, lymphocyte, and platelet (HALP) score is an indicator of inflammation and nutritional status. We aimed to evaluate the practicity of HALP score in non-ST elevation myocardial infarction (NSTEMI) patients.
Materials and Methods: This study was designed as a retrospective cohort study. Patients over the age of 18 who have been diagnosed with acute coronary syndrome were retrospectively searched from hospital records. The study groups were formed according to the results of the coronary angiography. Demographic data such as age, gender, total blood count, albümin levels, troponin levels and HALP scores of the patients were analyzed and comparisons between the groups were made decisively.
Results: 201 patients were enrolled in the study and the data was obtained from hospital records retrospectively. 79 patients were excluded from the study due to ST segment elevation myocardial infarction (STEMI). The study population was collected under two groups; the NSTEMI group (n=66) and normal coronary arteries (NCA) group (n=56). The mean age of NSTEMI group was 62.3 ± 11.8 and 71.2% (n=47) was male. The mean age of NCA group was 51.8 ± 9.2 and 30.3% (n=17) was male. There were statistically significant difference between NSTEMI and NCA groups in term of age and gender (p<0.05). The HALP score was statistically higher in NSTEMI group compared to NCA group (p<0.001). Age and HALP score have explanatory powers on NSTEMI patients (p=0.001 and p=0.022, in order of).
Conclusion: HALP score may be used as an easily applicable and inexpensive method in clinical practice that can contribute to the early diagnosis of NSTEMI patients.

Keywords

NSTEMI, emergency department, HALP score

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