PALYATİF AKCİĞER RADYOTERAPİSİ ALMIŞ HASTALARIN TAKİPLERİ: TEK MERKEZ DENEYİMİ

Year 2025, Volume: 8 Issue: 3, 251 - 256, 30.09.2025

Feryal Karaca , Sıddık Keskin , Ahmet Ziya Bayhan , Hakan Demir , Selahattin Menteş , Timuçin Çil

Abstract

Giriş: Akciğer kanseri (AK), en sık görülen malign tümörler arasındadır. Gelişmiş ülkelerde her iki cinsiyet için de önemli bir sağlık sorunudur. Evre-4 olan hastalarda kür mümkün değildir. Bu hastalara palyatif radyoterapi (RT), kemoterapi ve destekleyici bakım yapılmaktadır. Bu çalışmada, akciğerlerine palyatif RT almış Evre-4 hastalarda, sağkalım süresi ile bazı biyokimyasal özellikler arası ilişkinin incelenmesi amaçlanmıştır.
Gereç ve Yöntem: Çalışmaya 2016 Temmuz, 2022 Mayıs arasında hastanemizde akciğerlerine palyatif RT için başvuran 51 hasta dahil edilmiştir. Hastaların; yaşı, sağkalım süresi, cinsiyeti ve karsinom türü [Küçük hücreli dışı akciğer kanseri (KHDAK) ve küçük hücreli (KHAC)) ile birlikte; Alanin Aminotransferaz, Aspartat Aminotransferaz, Sodyum, Potasyum, Hematokrit, Hemoglobin, Lenfosit, Nötrofil, Platelet, Üre ve Laktat dehidrogenaz, değerleri ölçülmüştür. Bu özellikler için tanımlayıcı istatistikler ile birlikte korelasyon katsayıları hesaplanmıştır.
Bulgular: Hastaların tamamı Evre- 4 AK olup, 13 (%25.49) hasta kadın, 38 (%74.50) hasta ise erkektir. 41 (%80.39) hasta KHDAK, 10 (%19.60) hasta KHAK patolojisine sahiptir. Hastaların tamamına akciğerlerine yönelik palyatif RT verilmiştir. KHDAK tanılı hastaların medyan sağkalım süresi 18 hafta iken, KHAK patolojisine sahip hastalarda medyan sağkalım süresi 4 hafta olarak bulunmuştur.
Sonuç: Her iki grubu ait genel sağkalım süresi ise 16 hafta olarak bulunmuştur. Akciğerlerine yönelik palyatif RT Evre-4 AC hastalarda, sağkalım süresi ile birlikte bazı biyokimyasal özellikler arası ilişkiler belirlenmiştir. NSCLC grubu hastalarda sağkalım süresi, SCLC grubu hastalardan yaklaşık 4 kat daha yüksek bulundu.

Keywords

akciğer kanseri , radyoterapi, , sağkalım, , prognoz

Follow-up of Patients Who Received Palliative Lung Radiotherapy: A Single Center Experience

Abstract

Aim: Lung cancer (LC) is the most common among malignant tumors. Cure is not possible in patients with stage-4. These patients receive palliative radiotherapy (RT), chemotherapy and supportive care. This study aims to examine the relationship between survival time and some biochemical features in stage-4 patients who received palliative RT to their lungs.
Methods: 51 patients who applied to our hospital for palliative RT to their lungs between July 2016 and May 2022 were included in the study. All patients; age, survival rate, gender and type of carcinoma [non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC)]; alanine aminotransferase, aspartate amino transferase, sodium, potassium, hematocrit, hemoglobin, lymphocyte, neutrophil, platelet, urea and lactate dehydrogenase values were measured. Correlation coefficients along with descriptive statistics were computed for these features.
Resuls: All patients have stage-4 LC. 13 (25.49%) patients are female and 38 (74.50%) patients are male. NSCLC had 41(80.39%) of all patients, SCLC pathology had 10 (19.60%) of all patients.All patients received palliative RT to their lungs. While the median survival time for patients diagnosed with NSCLC was 18 weeks, the median survival time for patients with SCLC pathology was found 4 weeks.
Conclusion:The overall survival time for both groups was found 16 weeks. Relationships between survival time and some biochemical properties were determined in patients with stage-4 LC who received palliative RT to the lungs. Survival time in NSCLC group patients was found to be approximately 4 times higher than in SCLC group patients.

Keywords

lung cancer , prognosis , radiotherapy , survival

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