Oral hairy leukoplakia in the buccal mucosa of a healthy, HIV-negative patient

Abstract

Oral hairy leukoplakia (OHL), first described in 1984, is an Epstein-Barr virus lesion located laterally in the tongue and manifesting as a white, asymptomatic mucosal plaque which cannot be removed by scraping. OHL is more commonly observed in HIV-positive patients, in immunosuppressed patients after kidney, heart, liver and bone marrow transplantation, in hematological malignancies such as multiple myeloma, and in patients undergoing systemic or topical steroid therapy. OHL has rarely been reported in healthy patients who are not immunosuppressive. The case of an otherwise healthy, HIV-negative 24 year-old woman with OHL lesions in the buccal mucosa is presented here because of its rarity.

Keywords

• Oral hairy leukoplakia,HIV-negative patient,Buccal mucosa

Sağlıklı, HIV negatif bir hastada bukkal mukozada oral kıllı lökoplaki

Öz

İlk olarak 1984'te tanımlanan oral kıllı lökoplaki (OKL), sıklıkla dil lateralde yerleşen kazımakla çıkarılamayan beyaz renkli, asemptomatik mukozal plak olarak kendini gösteren bir Epstein-Barr virüsü lezyonudur. OKL daha çok HIV pozitif hastalarda bulunurken, böbrek, kalp, karaciğer ve kemik iliği transplantasyonu sonrası immünsüpresif hastalarda, multipl miyelom gibi hematolojik malignitelerde ve sistemik veya topikal steroid tedavisi altındaki hastalarda da tanımlanmıştır. Literatürde OKL, nadiren immünsüpresif olmayan sağlıklı hastalarda da bildirilmiştir. Burada,  24 yaşında diğer açılardan sağlıklı, HIV negatif, bukkal mukozada OKL lezyonu olan kadın hasta nadir görülmesi nedeniyle sunulmaktadır.

Anahtar Kelimeler

• Oral kıllı lökoplaki,HIV-negatif hasta,Bukkal mukoza

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