Characterization of Magnetic Polymeric Microparticles

Volume: 3 Number: 3 January 8, 2017
EN

Characterization of Magnetic Polymeric Microparticles

Abstract

The separation process is very important in a variety of scientific fields, especially in biochemistry and biotechnology. The separation performance of a method can be determined by the separation time and the purity of the separated molecule, which is directly proportional with the ligand chosen for the target molecule. The separation time is actually a very important step for the cost and the time-dependent analysis, especially in medical applications. Magnetic separation is a very advantageous technique because it eliminates the time-consuming sample preparation and centrifugation steps. However, the magnetic performance of adsorbent may not be strong enough to respond the magnetic force applied externally. Therefore, in nanoparticle studies, magnetic performance of nanoparticles is highly important. In this study, the magnetic performance of polymeric microparticles synthesized using different magnetic cores (Fe2O3&Fe3O4, Fe&Ni, Ni&Co, Fe&Ni&Co) with a solid support, HEMA (2-hydroxyl ethylmethacrylate), and a functional monomer, AdeM (adenine methacrylate), were compared. Some other properties such as size, zeta potential, surface morphology, etc. were also studied.

Keywords

References

  1. Josephson L, Tung C-H, Moore A, Weissleder R. High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates. Bioconjugate chemistry. 1999;10(2):186-91.
  2. Partington KM, Jenkinson EJ, Anderson G. A novel method of cell separation based on dual parameter immunomagnetic cell selection. Journal of immunological methods. 1999;223(2):195-205.
  3. Türkmen D, Yavuz H, Denizli A. Synthesis of tentacle type magnetic beads as immobilized metal chelate affinity support for cytochrome c adsorption. International journal of biological macromolecules. 2006;38(2):126-33.
  4. Park J-H, Im K-H, Lee S-H, Kim D-H, Lee D-Y, Lee Y-K, et al. Preparation and characterization of magnetic chitosan particles for hyperthermia application. Journal of Magnetism and Magnetic Materials. 2005;293(1):328-33.
  5. Lübbe AS, Alexiou C, Bergemann C. Clinical applications of magnetic drug targeting. Journal of Surgical Research. 2001;95(2):200-6.
  6. Hinds KA, Hill JM, Shapiro EM, Laukkanen MO, Silva AC, Combs CA, et al. Highly efficient endosomal labeling of progenitor and stem cells with large magnetic particles allows magnetic resonance imaging of single cells. Blood. 2003;102(3):867-72.
  7. Mornet S, Vasseur S, Grasset F, Duguet E. Magnetic nanoparticle design for medical diagnosis and therapy. Journal of Materials Chemistry. 2004;14(14):2161-75.
  8. Serda RE, Adolphi NL, Bisoffi M, Sillerud LO. Targeting and cellular trafficking of magnetic nanoparticles for prostate cancer imaging. Molecular imaging. 2007;6(4):277.

Details

Primary Language

English

Subjects

-

Journal Section

-

Publication Date

January 8, 2017

Submission Date

August 16, 2016

Acceptance Date

-

Published in Issue

Year 2016 Volume: 3 Number: 3

APA
Köse, K. (2017). Characterization of Magnetic Polymeric Microparticles. Journal of the Turkish Chemical Society Section A: Chemistry, 3(3), 185-204. https://doi.org/10.18596/jotcsa.74979
AMA
1.Köse K. Characterization of Magnetic Polymeric Microparticles. JOTCSA. 2017;3(3):185-204. doi:10.18596/jotcsa.74979
Chicago
Köse, Kazım. 2017. “Characterization of Magnetic Polymeric Microparticles”. Journal of the Turkish Chemical Society Section A: Chemistry 3 (3): 185-204. https://doi.org/10.18596/jotcsa.74979.
EndNote
Köse K (January 1, 2017) Characterization of Magnetic Polymeric Microparticles. Journal of the Turkish Chemical Society Section A: Chemistry 3 3 185–204.
IEEE
[1]K. Köse, “Characterization of Magnetic Polymeric Microparticles”, JOTCSA, vol. 3, no. 3, pp. 185–204, Jan. 2017, doi: 10.18596/jotcsa.74979.
ISNAD
Köse, Kazım. “Characterization of Magnetic Polymeric Microparticles”. Journal of the Turkish Chemical Society Section A: Chemistry 3/3 (January 1, 2017): 185-204. https://doi.org/10.18596/jotcsa.74979.
JAMA
1.Köse K. Characterization of Magnetic Polymeric Microparticles. JOTCSA. 2017;3:185–204.
MLA
Köse, Kazım. “Characterization of Magnetic Polymeric Microparticles”. Journal of the Turkish Chemical Society Section A: Chemistry, vol. 3, no. 3, Jan. 2017, pp. 185-04, doi:10.18596/jotcsa.74979.
Vancouver
1.Kazım Köse. Characterization of Magnetic Polymeric Microparticles. JOTCSA. 2017 Jan. 1;3(3):185-204. doi:10.18596/jotcsa.74979

Cited By