Novel lanthanide metallophthalocyanines bearing iodine group and their singlet oxygen generation ability

Year 2022, Volume: 9 Issue: 3, 741 - 750, 31.08.2022

Baybars Köksoy

Abstract

In this study, five novel mono rare earth metallo phthalocyanine derivatives (1a-e) were synthesized by cyclotetramerization of 4-iodophthalonitrile and corresponding metal salts. These novel compounds were characterized by IR, elemental analyses, UV–vis, and MALDI-TOF spectral data. Moreover, the ability of singlet oxygen generation and aggregation behaviour of these phthaloyanines were investigated in dimethyl sulfoxide using UV-Vis spectroscopy. Gadolinium metallo phthalocyanine has the best singlet oxygen quantum yield and it can be a potential candidate for the photodynamic therapy (PDT) of cancer.

Keywords

Phthalocyanine, Iodine, Lanthanide, Singlet Oxygen

Thanks

Synthesis and measurements were performed at Gebze Technical University, and I want to thank Prof. Dr. Mahmut DURMUŞ.

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