Synthesis, Characterization and Radical Scavenging Activities of 1,3-Disubstituted Benzimidazolium Salts

Year 2025, Volume: 8 Issue: 1, 91 - 102, 17.06.2025

Serpil Demir Düşünceli , Buket Karatepe , Serhat Keser

Abstract

The reaction of N-substituted benzimidazole and alkyl halides (benzyl bromoacetate and trifluoromethoxybenzyl bromide) gave a series of 1,3-disubstituted benzimidazolium salts. The structure of synthesized compounds was confirmed by various spectroscopic techniques such as 1H, 13C and 19F NMR spectroscopy, FT-IR and elemental analysis. Biological efficiency of these compounds was evaluated by antioxidant activities like ABTS, OH and DPPH radical scavenging activity.

Keywords

Benzimidazolium salt, trifluoromethoxy, ester group, antioxidant activity

Ethical Statement

not necessary

Supporting Institution

İnonu University

Project Number

FLO-2024-3506

Thanks

The research is financially supported by the İnönü University Research Fund (İ.Ü. B.A.P. Project No: FLO-2024-3506).

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