Immunotherapy in Allergic Rhinitis
Abstract
Allergic rhinitis is an immunologic disorder that develops in individuals who have produced allergen-specific immunoglobulin E in response to environmental exposures (most commonly to pollens, animal dander, insect debris, and molds). For patients with a severe allergy that is not responsive to environmental controls and pharmacotherapy or for those who do not wish to use medication for a lifetime, immunotherapy may be offered. Specific immunotherapy as practiced since hundred years in Western Europe and the USA. Different routes for specific immunotherapy have been evaluated, such as the subcutaneous, sublingual, oral, nasal, bronchial, and intra-lymphatic, the first 2 of these routes being the most commonly used today in clinical practice. In this article, subcutaneous and sublingual immunotherapy in allergic rhinitis is reviewed.
Keywords
References
- Strachan D, Sibbald B, Weiland S, Aït-Khaled N, Anabwani G, Anderson HR et al. Worldwide variations in prevalence of symptoms of allergic rhinoconjunctivitis in children: the International Study of Asthma and Allergies in Childhood (ISAAC). Pediatr Allergy Immunol 1997;8:161– 76.
- Bjorksten B, Clayton T, Ellwood P, Stewart A, Strachan D.Worldwide time trends for symptoms of rhinitis and conjunctivitis: phase III of the International Study of Asthma and Allergies in Childhood. 2008;19:110– 24. Allergy Immunol
- Linneberg A, Nielsen NH, Frolund L, Madsen F, Dirksen A, Jorgensen T. The link between allergic rhinitis and allergic asthma: a prospective population-based study. The Copenhagen Allergy Study. Allergy 2001; 57:1048–52.
- Calderon MA, Alves B, Jacobson M, Hurwitz B, Sheikh A, Durham S. Allergen injection immunotherapy for seasonal allergic rhinitis. Cochrane (1):CD001936. SystRev 2007;
- Bousquet J, Schünemann HJ, Samolinski B, Demoly P, Baena-Cagnani CE, Bachert C et al. Allergic rhinitis and its impact on asthma. achievements in 10 years and future needs. J Allergy Clin Immunol 2001;108:147–334.
- Bufe A, Roberts G. Specific immunotherapy in children. Clin Exp Allergy 2011;41:1256-62.
- Bousquet J, Lockey R, Malling HJ, Alvarez- Cuesta E, Canonica GW, Chapman MD Allergen immunotherapy: therapeutic vaccines for allergic diseases. World Health Organization. American academy of Allergy, Asthma and Immunology. J Allergy Clin Immunol 1998;81:401–5.
- Cox L, T.Li James, Lockey R, Nelson H, Bernstein D, Bernstein L, et al. Allergen immunotherapy: a practice parameter second update. J Allergy Clin Immunol 2007;120:25–85.
Details
Primary Language
English
Subjects
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Journal Section
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Publication Date
January 7, 2015
Submission Date
January 22, 2015
Acceptance Date
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Published in Issue
Year 1970 Volume: 7 Number: 0