Wilms' tumour a€“ an update

Year 2010, Volume: 2 Issue: 3, 0 - , 11.06.2010

John Lazarus , Lisa Kaestner

Abstract

Wilms' Tumour accounts for 6% of all paediatric cancers. With modern multimodal therapy outcomes for patients is generally good (with an overall survival of >90%) and a reduction in treatment related morbidity. This review highlights recent developments risk stratification using histological grade and tumour stage. A rational approach to workup of these children is presented focusing on imaging interpretation. Management is discussed with emphasis on surgical technique and an update of chemotherapeutic strategies.

Keywords

Wilms tumor, children, diagnosis, therapy