Hematopoietic stem cell transplantation (HSCT) has been an established as a curative therapy for the various hematologic nonmalignant and malignant diseases in childhood. In addition to conventional indications like hematological malignancies, aplastic anemia and solid tumours, a gerat deal of inborn errors in children can be cured with HSCT. Recent applications and recommendations in terms of stem cell sources, indications, conditioning and post-transplant complications in children like infectious complications, graft versus host disease (GVHD), gastrointestinal and liver complications, pulmonary complications and late endocrine effects are discussed in this review.
Primary Language | English |
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Journal Section | Reviews |
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Publication Date | June 11, 2010 |
Published in Issue | Year 2010 Volume: 2 Issue: 3 |