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Neurological complications of gastrointestinal disorders. A review of the literature.

Year 2014, Volume: 6 , - , 01.01.2014

Anastasia Gkampeta , Evangelos Pavlou

https://doi.org/10.17334/jps.80498
Cited By: 1

Abstract

This article presents a short review of the literature concerning neurological complications of gastrointestinal disorders. These disorders include the following: inflammatory bowel diseases (ulcerative colitis, Crohn's disease), celiac disease, H. Pylori infection, hepatitis C, Wilson's disease, hepatic failure-liver transplantation, gastroenteritis. The most frequent neurological complications are peripheral neuropathy, cerebellar dysfunction, thromboembolism. The exact pathophysiologic mechanism remains unclear. In most cases neurological manifestations are the first clinical manifestation of the disease.

Keywords

neurological; complications; gastrointestinal

References

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Year 2014, Volume: 6 , - , 01.01.2014

Anastasia Gkampeta , Evangelos Pavlou

https://doi.org/10.17334/jps.80498
Cited By: 1

Abstract

References

  • Watts DA, Satsangi J. The genetic jigsaw of inflammatory bowel disease. Gut 2002;50:31–6.
  • Elsehety A, Bertorini TE. Neurologic and neuropsychiatric complications of Crohn's disease. South Med J 1997;90: 606–10.
  • Greenstein AJ, Janowitz HD, Sachar DB. The extra-intestinal complications of Crohn's disease and ulcerative colitis: a study of 700 patients. Medicine 1976;55:401–12.
  • Rankin GB, Watts HD, Melnyk CS, Kelley ML Jr. National Cooperative Crohn's Disease Study: extraintestinal manifestations and perianal complications. Gastroenterology 1979;77:914–20.
  • Lossos A, River Y, Eliakim A, Steiner I. Neurologic aspects in inflammatory bowel disease. Neurology 1995;45:416–
  • Maisawa S, Sasaki M, Ida S, Uchida K, Kagimoto S, Shimizu T, et al. Characteristics of inflammatory bowel disease with an onset before eight years of age: a multicenter epidemiological survey in Japan.J Gastroenterol Hepatol 2013;28:499-504.
  • Zois CD, Katsanos KH, Kosmidou M, Tsianos EV. Neurologic manifestations in inflammatory bowel diseases: current knowledge and novel insights. J Crohns Colitis 2010;4:115-24.
  • Green JR, O'Donoghue DP, Edwards CR, Dawson AM. A case of apparent hypopituitarism complicating chronic inflammatory bowel disease in childhood and adolescence. Acta Paediatr Scand 1977;66:643-7.
  • Greco F, Pavone P, Falsaperla R, Sorge G. Peripheral neuropathy as first sign of ulcerative colitis in a child. J Clin Gastroenterol 2004;38:115-7.
  • Ståhlberg D, Bárány F, Einarsson K, Ursing B, Elmqvist D, Persson A. Neurophysiologic studies of patients with Crohn's disease on long-term treatment with metronidazole. Scand J Gastroenterol 1991;26:219–24.
  • Gondim FA, Brannagan TH 3rd, Sander HW, Chin RL, Latov N. Peripheral neuropathy in patients with inflammatory bowel disease. Brain 2005;128:867–79.
  • Yeşilova Z, Naharci I, Uygun A, Ulaş HU, Dağalp K. Motor axonal polyneuropathy in the course of ulcerative colitis: a case report. Turk J Gastroenterol 2006;17:58–61.
  • Berden JH, Hoitsma AJ, Merx JL, Keyser A. Severe central nervous system toxicity associated with cyclosporine. Lancet 1985;1: 219–20.
  • Porges Y, Blumen S, Fireman Z, Sternberg A, Zamir D. Cyclosporineinduced optic neuropathy, ophthalmoplegia and nystagmus in a patient with Crohn's disease. Am J Ophthalmol 1998;126:607–9.
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  • Nguyen LT, Laberge JM, Guttman FM, Albert D. Spontaneous deep vein thrombosis in childhood and adolescence. J Pediatr Surg 1986;21:640-3.
  • Goodwin FC, Beattie RM, Millar J, Kirkham FJ. Celiac disease and childhood stroke. Pediatr Neurol 2004;31:139-42.
  • Purrmann J, Arendt G, Cleveland S, Borchard F, Fürst W, Gemsa R, et al. Association of Crohn's disease and multiple sclerosis. Is there a common background? J Clin Gastroenterol 1992;14:43–6.
  • Buccino GP, Corrente G, Visintini D. Crohn's disease and multiple sclerosis:a single case report. Ital J Neurol Sci 1994;15:303–6.
  • Kitchin LI, Knobler RL, Friedman LS. Crohn's disease in a patient with multiple sclerosis. J Clin Gastroenterol 1991;13: 331–
  • Ghezzi A, Zaffaroni M. Neurological manifestations of gastrointestinal disorders, with particular reference to the differential diagnosis of multiple sclerosis. Neurol Sci 2001;22 Suppl 2:117-22.
  • Beaugerie L, Lamy P, Ganne N, Carbonnel F, Le Quintrec Y, Cosnes J, et al. Morbid associations in Crohn's disease. Study of a series of 832 patients. Presse Med 1997;26:892–4.
  • Martin RW, Shah A. Myasthenia Gravis coexistent with Crohn's disease. J Clin Gastroenterol 1991;13:112–3.
  • Gelfenbeyn M, Goodkin R, Kliot M. Sterile recurrent spinal epidural abscess in a patient with Crohn's disease: a case report. Surg Neurol 2006;65:178–84.
  • Marks J, Shuster S, Watson AJ. Small bowel changes in dermatitis herpetiformis. Lancet 1966; 1280–2.
  • Cooke WT, Smith WT. Neurological disorders associated with adult coeliac disease. Brain 1966;89:683–722.
  • Finelli PF, McEntee WJ, Ambler M, Kestenbaum D. Adult celiac disease presenting as cerebellar syndrome. Neurology 1980;30:245–9. Hadjivassiliou M, Sanders DS, Grünewald RA, Woodroofe N, Boscolo S, Aeschlimann D. The neurology of gluten sensitivity. Lancet Neurol 2010; 9: 330–42.
  • Gobbi G, Bouquet F, Greco L, Lambertini A, Tassinari CA, Ventura A, et al. Coeliac disease, epilepsy and cerebral calcifi cations. Lancet 1992; 340: 439–43.
  • Ghezzi A, Filippi M, Falini A, Zaffaroni M. Cerebral involvement in celiac disease: a serial MRI study in a patient with brainstem and cerebellar symptoms. Neurology 1997;49:1447–50.
  • Ward ME, Murphy JT, Greenberg GR. Celiac disease and spinocerebellar degeneration with normal vitamin E status. Neurology 1985;35:1199–1201.
  • Beversdorf D, Moses P, Reeves A, Dunn J. A man with weight loss, ataxia, and confusion for 3 months. Lancet 1996;347:446. Hadjivassiliou M, Aeschlimann P, Strigun A, Sanders DS, Woodroofe N, Aeschlimann D. Autoantibodies in gluten ataxia recognise a novel neuronal transglutaminase. Ann Neurol 2008; 64: 332–43. Hadjivassiliou M, Aeschlimann P, Sanders DS, et al. Antibodies against TG6 as the only serological marker of gluten ataxia. Proceedings of the 13th nternational Coeliac Disease Symposium. Amsterdam; April 6–8, 200 09.1.
  • Wilkinson ID, Hadjivassiliou M, Dickson JM, Wallis L, Grünewald RA, Coley SC, et al. Cerebellar abnormalities on proton MR spectroscopy in gluten ataxia. J Neurol Neurosurg Psychiatry 2005; 76: 1011–13.
  • Luostarinen L, Himanen SL, Luostarinen M, Collin P, Pirttila T. Neuromuscular and sensory disturbances in patients with well treated celiac disease. J Neurol Neurosurg Psychiatry 2003; 74: 490–4.
  • Hadjivassiliou M, Grünewald RA, Kandler RH, Chattopadhyay AK, Jarratt JA, Sanders DS, et al. Neuropathy associated with gluten sensitivity. J Neurol Neurosurg Psychiatry 2006; 77: 1262–6.
  • Chapman RWG, Laidlow JM, ColinJones D, Eade OE, Smith CL. Increased prevalence of epilepsy in coeliac disease BMJ. 1978; 2: 250–1.
  • Fois A, Vascotto M, Di Bartolo RM, Di Marco V. Celiac disease and epilepsy in pediatric patients. Childs Nerv Syst 1994; 10: 450–4.
  • Cronin CC, Jackson LM, Feighery C, Shanahan F, Abuzakouk M, Ryder DQ, et al. Coeliac disease and epilepsy Q JM. 1998; 91: 303–8.
  • Gobbi G, Bouquet F, Greco L, Lambertini A, Tassinari CA, Ventura A, et al. Coeliac disease, epilepsy and cerebral calcifi cations. Lancet 1992; 340: 439–43.
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There are 98 citations in total.

Details

Primary Language English
Journal Section Reviews
Authors

Anastasia Gkampeta

Evangelos Pavlou This is me

Publication Date January 1, 2014
Published in Issue Year 2014 Volume: 6

Cite

APA Gkampeta, A., & Pavlou, E. (2014). Neurological complications of gastrointestinal disorders. A review of the literature. Journal of Pediatric Sciences, 6. https://doi.org/10.17334/jps.80498
AMA Gkampeta A, Pavlou E. Neurological complications of gastrointestinal disorders. A review of the literature. Journal of Pediatric Sciences. January 2014;6. doi:10.17334/jps.80498
Chicago Gkampeta, Anastasia, and Evangelos Pavlou. “ A Review of the Literature”. Journal of Pediatric Sciences 6, January (January 2014). https://doi.org/10.17334/jps.80498.
EndNote Gkampeta A, Pavlou E (January 1, 2014) Neurological complications of gastrointestinal disorders. A review of the literature. Journal of Pediatric Sciences 6
IEEE A. Gkampeta and E. Pavlou, “ A review of the literature”., Journal of Pediatric Sciences, vol. 6, 2014, doi: 10.17334/jps.80498.
ISNAD Gkampeta, Anastasia - Pavlou, Evangelos. “ A Review of the Literature”. Journal of Pediatric Sciences 6 (January 2014). https://doi.org/10.17334/jps.80498.
JAMA Gkampeta A, Pavlou E. Neurological complications of gastrointestinal disorders. A review of the literature. Journal of Pediatric Sciences. 2014;6. doi:10.17334/jps.80498.
MLA Gkampeta, Anastasia and Evangelos Pavlou. “ A Review of the Literature”. Journal of Pediatric Sciences, vol. 6, 2014, doi:10.17334/jps.80498.
Vancouver Gkampeta A, Pavlou E. Neurological complications of gastrointestinal disorders. A review of the literature. Journal of Pediatric Sciences. 2014;6.

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