Abstract
References
- American Academy of Pediatrics Committee on Drugs: Guidelines for monitoring and management of pediatric patients during and after sedation for diagnostic and therapeutic procedures. Pediatrics 1992; 89: 1110-15.
- Bauman LA, Kish I, Baumann RC, Polities GD: Pediatric sedation with analgesia. Am J Emerg Med 1999; 17: 1-3.
- Ross PJ, Fochtman D: Conscious sedation: a quality management project. J Pediatric Oncol Nurs 1995; 12: 115-21.
- Andrews JS: Conscious sedation in the pediatric emergency department. Curr Opin Pediatric 1995; 7:309-13.
- Petrack EM, Marx CM, and Wright MS: Intramuscular ketamine is superior to meperidine, chlorpromazine for pediatric emergency department sedation. Arch Pediatric Adolesc Med 1996; 150: 676-81. and
- Gudlin DJ, Winch AE, Kochevar W: Ask the expert: conscious sedation. J Soc Pediatric Nurs 1997; 2: 143-7.
- Holloway VJ, Husain HM, Saetta JP, et al: Accident and emergency department led implementation of ketamine sedation in pediatric practice and parental response. J Accid Emerg Med 2000; 17: 25-8.
- Dachs RJ, Innes G: Intravenous ketamine sedation of pediatric patients in the emergency department. Annals Emerg Med. 1997; 29:146-150.
- Green SM, Johnson NE. Ketamine sedation for pediatric procedures: Part 2, review and implications. Annals Emerg Med. 1990; 19:1033-46.
- Green SM, Johnson NE. Ketamine sedation for pediatric procedures: Part 2, review and I implications. Annals Emerg Med. 1990; 19:1033-46.
- Lohit K, Srinivas V, Kulkarni C, Shaheen: A clinical evaluation of the effects of administration of midazolam on ketamine induced emergence phenomenon. Journal of clinical and diagnostic research 2011; 5: 320- 323.
- Mistry RB, Nahata MC: Ketamine for conscious sedation in pediatric emergency care. Pharmacotherapy. 2005;25:1104-11.
To study the efficacy and safety of injectable ketamine in pediatric ward procedure in age group of 6 month to 12 year in tertiary care hospital
Abstract
Background: The literature concerning the efficacy and safety of ketamine for conscious sedation during procedures in pediatric ward was reviewed.
Aims: To see the efficacy and safety of injectable ketamine in pediatric ward procedure in age group of 6 month to 12 year in tertiary care hospital and parental satisfaction. Settings and Design: prospective unicentric, interventional, pilot study. Patients admitted in pediatric ward in tertiary care medical college hospital.
Methods and Material: Ketamine 1mg/kg intravenously given in fifteen-twenty second to patients goes into different ward procedure except in exclusion criteria. If adequate effect not produced within five minutes, same dose is repeated. Time required for dissociation, duration of effect, pre & post procedural heart rate, respiratory rate, blood pressure and oxygen saturation and other significant side effects were recorded after five & thirty minutes. Vitals and behaviour monitoring was done for twenty four hours after procedure. Statistical analysis used: basic biostatistics used.
Results: During study period twenty three patients were studied. Three patients were excluded from data analysis in study as per exclusion criteria. Twenty patients were analyzed. Peak effect seen within one to five minute after injection. Heart rate, respiratory rate, systolic and diastolic blood pressure rise in all patients and return to base line after thirty minute. Side effect including vomiting seen in one patient and increase salivation in five patients but no active management required. Repeat dose required in three patients.
Conclusions: we found that ketamine in dose of 1mg/kg is alone effective and safe drug and is suitable for use in children requiring conscious sedation for variety of painful and anxiety producing procedures with good parental satisfaction. Side effects encountered were minimal and no intensive management required in any patient due to side effects.
References
- American Academy of Pediatrics Committee on Drugs: Guidelines for monitoring and management of pediatric patients during and after sedation for diagnostic and therapeutic procedures. Pediatrics 1992; 89: 1110-15.
- Bauman LA, Kish I, Baumann RC, Polities GD: Pediatric sedation with analgesia. Am J Emerg Med 1999; 17: 1-3.
- Ross PJ, Fochtman D: Conscious sedation: a quality management project. J Pediatric Oncol Nurs 1995; 12: 115-21.
- Andrews JS: Conscious sedation in the pediatric emergency department. Curr Opin Pediatric 1995; 7:309-13.
- Petrack EM, Marx CM, and Wright MS: Intramuscular ketamine is superior to meperidine, chlorpromazine for pediatric emergency department sedation. Arch Pediatric Adolesc Med 1996; 150: 676-81. and
- Gudlin DJ, Winch AE, Kochevar W: Ask the expert: conscious sedation. J Soc Pediatric Nurs 1997; 2: 143-7.
- Holloway VJ, Husain HM, Saetta JP, et al: Accident and emergency department led implementation of ketamine sedation in pediatric practice and parental response. J Accid Emerg Med 2000; 17: 25-8.
- Dachs RJ, Innes G: Intravenous ketamine sedation of pediatric patients in the emergency department. Annals Emerg Med. 1997; 29:146-150.
- Green SM, Johnson NE. Ketamine sedation for pediatric procedures: Part 2, review and implications. Annals Emerg Med. 1990; 19:1033-46.
- Green SM, Johnson NE. Ketamine sedation for pediatric procedures: Part 2, review and I implications. Annals Emerg Med. 1990; 19:1033-46.
- Lohit K, Srinivas V, Kulkarni C, Shaheen: A clinical evaluation of the effects of administration of midazolam on ketamine induced emergence phenomenon. Journal of clinical and diagnostic research 2011; 5: 320- 323.
- Mistry RB, Nahata MC: Ketamine for conscious sedation in pediatric emergency care. Pharmacotherapy. 2005;25:1104-11.
Details
| Primary Language | English |
|---|---|
| Subjects | Clinical Sciences |
| Journal Section | Original Articles |
| Authors | |
| Publication Date | January 7, 2015 |
| Published in Issue | Year 2015 Volume: 7 |