Genetics of Risk-Taking Behavior: Current Knowledge, Challenges and Future Directions

Nilay Ateşyakar; Elif Aysimi Duman

doi:10.19168/jyasar.826953

Derleme

Genetics of Risk-Taking Behavior: Current Knowledge, Challenges and Future Directions

Yıl 2021, , 718 - 738, 30.04.2021

Nilay Ateşyakar Elif Aysimi Duman

https://doi.org/10.19168/jyasar.826953

Cited By: 1

Öz

Our daily decisions reflect continuous assessments of risk that highly varies from one individual to the other. Research on the underlying mechanisms of individual differences in risk-taking behavior emphasizes changes in neural and physiological pathways that is in part due to the activation of different neurotransmitter systems. Consequently, genetic variations in these systems were the primary target of studies investigating the genetic underpinnings of risk-taking behavior. The aim of this review is to give an overview of our current knowledge related to genetic variations in these systems and economic risk-taking behavior. We first examine candidate gene association studies, followed by genome-wide association and gene-environment interaction studies utilizing different measures of risk-taking to illustrate the progress in the field. Considering the characteristics and results of these studies, we then discuss the limitations and challenges in research with suggestions for future directions.

Anahtar Kelimeler

risk-taking behavior, financial risk-taking, behavioral economics, genoeconomics, genetic differences

Destekleyen Kurum

Bogazici University

Proje Numarası

BAP Grant #14327

Kaynakça

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Risk Alma Davranişinin Genetiği: Güncel Bilgiler, Zorluklar ve Geleceğe Yönelik Öneriler

Yıl 2021, , 718 - 738, 30.04.2021

Nilay Ateşyakar Elif Aysimi Duman

https://doi.org/10.19168/jyasar.826953

Cited By: 1

Öz

Günlük kararlarımız, bir kişiden diğerine oldukça değişen ve süregelen risk değerlendirmelerimizi yansıtır. Risk-alma davranışındaki bireysel farklılıkların altında yatan mekanizmaları araştıran çalışmalar, kısmen farklı nörotransmitter sistemlerinin aktivasyonuyla ilişkili sinirsel ve fizyolojik yolaklardaki değişikliklerin önemini vurgulamaktadır. O nedenle, risk-alma davranışının genetik dayanaklarıyla ilgili araştırmaların öncelikli hedefi, bu sistemlerdeki genetik farklılıklar olmuştur. Bu derlemenin amacı, bu sistemlerdeki genetik farklılıklar ve ekonomik risk-alma davranışı ile ilgili güncel bilgilerimize genel bir bakış sunmaktır. Alandaki gelişimi göstermek için öncelikle farklı risk-alma ölçümleri kullanan aday gen ilişkilendirme çalışmalarının bulguları, sonrasında da genom boyu ilişkilendirme ve gen-çevre etkileşimi çalışmalarının bulguları incelenecektir. Son olarak, bu araştırmaların özellikleri ve sonuçları göz önünde bulundurularak, araştırmalardaki sınırlamalar ve zorluklar tartışılacak ve gelecek araştırmalar için öneriler sunulacaktır.

Anahtar Kelimeler

risk alma davranışı, finansal risk alma, davranışsal ekonomi, genoekonomi, genetik farklılıklar

Proje Numarası

BAP Grant #14327

Kaynakça

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Schultz, Wolfram. 2007. “Behavioral Dopamine Signals.” Trends in Neurosciences 30 (5): 203–10. https://doi.org/10.1016/j.tins.2007.03.007.
Senn, Theresa E., and Michael P. Carey. 2010. “Child Maltreatment and Women’s Adult Sexual Risk Behavior: Childhood Sexual Abuse as a Unique Risk Factor.” Child Maltreatment 15 (4): 324–35. https://doi.org/10.1177/1077559510381112.
Srivastava, Mrinalini, Gagan Deep Sharma, Achal Kumar Srivastava, and S. Senthil Kumaran. 2020. “What’s in the Brain for Us: A Systematic Literature Review of Neuroeconomics and Neurofinance.” Qualitative Research in Financial Markets 12 (4): 413–35. https://doi.org/10.1108/qrfm-10-2019-0127.
Stamatis, Caitlin A., Jan B. Engelmann, Christiane Ziegler, Katharina Domschke, Gregor Hasler, and Kiara R. Timpano. 2020. “A Neuroeconomic Investigation of 5-HTT/5-HT1A Gene Variation, Social Anxiety, and Risk-Taking Behavior.” Anxiety, Stress and Coping 33 (2): 176–92. https://doi.org/10.1080/10615806.2020.1722597.
Stoltenberg, Scott F., Melissa K. Lehmann, Cynthia Anderson, Parthasarathi Nag, and Cheryl Anagnopoulos. 2011. “Serotonin Transporter (5-HTTLPR) Genotype and Childhood Trauma Are Associated with Individual Differences in Decision Making.” Frontiers in Genetics 2 (JUNE): 1–9. https://doi.org/10.3389/fgene.2011.00033.
Stoltenberg, Scott F., and Joanna M. Vandever. 2010. “Gender Moderates the Association between 5-HTTLPR and Decision-Making under Ambiguity but Not under Risk.” Neuropharmacology 58 (2): 423–28. https://doi.org/10.1016/j.neuropharm.2009.09.010.
Strawbridge, Rona J., Joey Ward, Breda Cullen, Elizabeth M. Tunbridge, Sarah Hartz, Laura Bierut, Amy Horton, et al. 2018. “Genome-Wide Analysis of Self-Reported Risk-Taking Behaviour and Cross-Disorder Genetic Correlations in the UK Biobank Cohort.” Translational Psychiatry 8 (1): 1–11. https://doi.org/10.1038/s41398-017-0079-1.
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Webber, Troy A., Heather E. Soder, Geoffrey F. Potts, Jong Y. Park, and Marina A. Bornovalova. 2017. “Neural Outcome Processing of Peer-Influenced Risk-Taking Behavior in Late Adolescence: Preliminary Evidence for Gene × Environment Interactions.” Experimental and Clinical Psychopharmacology 25 (1): 31–40. https://doi.org/10.1037/pha0000105.
Xu, Sihua, Marc Korczykowski, Senhua Zhu, and Hengyi Rao. 2013. “Assessment of Risk-Taking and Impulsive Behaviors: A Comparison between Three Tasks.” Social Behavior and Personality 41 (3): 477–86. https://doi.org/10.2224/sbp.2013.41.3.477.
Zak, Paul J. 2004. “Neuroeconomics.” Philosophical Transactions of the Royal Society B: Biological Sciences 359 (1451): 1737–48. https://doi.org/10.1098/rstb.2004.1544.
Zhong, Songfa, Salomon Israel, Hong Xue, Richard P. Ebstein, and Soo Hong Chew. 2009b. “Monoamine Oxidase A Gene (MAOA) Associated with Attitude towards Longshot Risks.” PLoS ONE 4 (12): e8516. https://doi.org/10.1371/journal.pone.0008516.
Zhong, Songfa, Salomon Israel, Hong Xue, Pak C. Sham, Richard P. Ebstein, and Soo Hong Chew. 2009a. “A Neurochemical Approach to Valuation Sensitivity over Gains and Losses.” Proceedings of the Royal Society B: Biological Sciences 276 (1676): 4181–88. https://doi.org/10.1098/rspb.2009.1312.
Zuckerman, Marvin, and D. Michael Kuhlman. 2000. “Personality and Risk-Taking: Common Biosocial Factors.” Journal of Personality 68 (6): 999–1029. https://doi.org/10.1111/1467-6494.00124.
Zyphur, M. J., J. Narayanan, R. D. Arvey, and G. J. Alexander. 2009. “The Genetics of Economic Risk Preferences.” Journal of Behavioral Decision Making 22 (4): 367–77. https://doi.org/10.1002/bdm.

Toplam 97 adet kaynakça vardır.

Ayrıntılar

Birincil Dil	İngilizce
Bölüm	Makaleler
Yazarlar	Nilay Ateşyakar Bu kişi benim 0000-0002-4540-5445 Elif Aysimi Duman 0000-0003-0973-6869
Proje Numarası	BAP Grant #14327
Yayımlanma Tarihi	30 Nisan 2021
Yayımlandığı Sayı	Yıl 2021

Kaynak Göster

APA	Ateşyakar, N., & Duman, E. A. (2021). Genetics of Risk-Taking Behavior: Current Knowledge, Challenges and Future Directions. Yaşar Üniversitesi E-Dergisi, 16(62), 718-738. https://doi.org/10.19168/jyasar.826953
AMA	Ateşyakar N, Duman EA. Genetics of Risk-Taking Behavior: Current Knowledge, Challenges and Future Directions. Yaşar Üniversitesi E-Dergisi. Nisan 2021;16(62):718-738. doi:10.19168/jyasar.826953
Chicago	Ateşyakar, Nilay, ve Elif Aysimi Duman. “Genetics of Risk-Taking Behavior: Current Knowledge, Challenges and Future Directions”. Yaşar Üniversitesi E-Dergisi 16, sy. 62 (Nisan 2021): 718-38. https://doi.org/10.19168/jyasar.826953.
EndNote	Ateşyakar N, Duman EA (01 Nisan 2021) Genetics of Risk-Taking Behavior: Current Knowledge, Challenges and Future Directions. Yaşar Üniversitesi E-Dergisi 16 62 718–738.
IEEE	N. Ateşyakar ve E. A. Duman, “Genetics of Risk-Taking Behavior: Current Knowledge, Challenges and Future Directions”, Yaşar Üniversitesi E-Dergisi, c. 16, sy. 62, ss. 718–738, 2021, doi: 10.19168/jyasar.826953.
ISNAD	Ateşyakar, Nilay - Duman, Elif Aysimi. “Genetics of Risk-Taking Behavior: Current Knowledge, Challenges and Future Directions”. Yaşar Üniversitesi E-Dergisi 16/62 (Nisan 2021), 718-738. https://doi.org/10.19168/jyasar.826953.
JAMA	Ateşyakar N, Duman EA. Genetics of Risk-Taking Behavior: Current Knowledge, Challenges and Future Directions. Yaşar Üniversitesi E-Dergisi. 2021;16:718–738.
MLA	Ateşyakar, Nilay ve Elif Aysimi Duman. “Genetics of Risk-Taking Behavior: Current Knowledge, Challenges and Future Directions”. Yaşar Üniversitesi E-Dergisi, c. 16, sy. 62, 2021, ss. 718-3, doi:10.19168/jyasar.826953.
Vancouver	Ateşyakar N, Duman EA. Genetics of Risk-Taking Behavior: Current Knowledge, Challenges and Future Directions. Yaşar Üniversitesi E-Dergisi. 2021;16(62):718-3.

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