Tek Merkez Deneyimi: Feokromasitoma Olgularının Retrospektif Değerlendirilmesi

Murat Çalapkulu; Muhammed Erkam Sencar; İlknur Östürk Ünsal; Davut Sakız; Mustafa Özbek; Erman Çakal

Tek Merkez Deneyimi: Feokromasitoma Olgularının Retrospektif Değerlendirilmesi

Abstract

Amaç: Feokromositomalar kromaffin hücrelerinden kaynaklanan nöroendokrin tümörlerdir. Bu çalışmanın amacı feokromasitoma hastalarının klinik, laboratuvar ve görüntüleme bulgularını gözden geçirmektir. Materyal ve Metot: Araştırmamızda 2009–2019 yılları arasında feokromasitoma tanısı almış 19 olguya ait klinik, laboratuvar ve radyolojik veriler geriye dönük olarak değerlendirilmiştir. Bulgular: Feokromasitoma tanısı konan 19 hastadan 13’ü kadın, 6’sı erkek olup ortalama yaş 44,1±11,3 yıl olarak saptandı. Hastaların 8 tanesi yeni tanı olmak üzere 18’inde hipertansiyon mevcuttu. Feokromositoma hastalarına eşlik eden hastalıklar incelendiğinde, hipertansiyondan sonra en sık tiroid patolojilerinin olduğu bulundu. Tansiyon yüksekliğinden sonra en sık semptom terleme ve baş ağrısı olarak saptandı. Tüm hastalarda vitamin D eksikliği ya da yetersizliği mevcuttu. Hastaların %94,1’inde 24 saatlik idrarda bakılan normetanefrin düzeyi yüksek olarak saptandı. Yerleşim yerleri açısından on birinde sağda, beşinde solda ve üçünde tümör bilateral adrenal yerleşimliydi. Lezyon boyutu %36,8’inde 4 cm’den küçük, %42,1’inde 4–6 cm arasında saptanırken, %21,1’inde 6 cm’den büyük saptandı. Sonuç: Bu çalışma feokromasitomanın nonspesifik ve değişken bir kliniğinin olduğunu gösterdi. Feokromasitoma şüphesi olan hastalarda özellikle ataklar sırasında tarama testi olarak 24 saatlik idrarda normetanefrin ve metanefrin düzeyleri istenmeli ve görüntüleme yöntemleri ile kitle lokalize edildikten sonra cerrahi tedavi uygulanmalıdır.

Keywords

References

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Details

Primary Language

Turkish

Subjects

Clinical Sciences

Journal Section

Research Article

Authors

Murat Çalapkulu
Türkiye

Muhammed Erkam Sencar This is me
Türkiye

İlknur Östürk Ünsal This is me
Türkiye

Davut Sakız This is me
Türkiye

Mustafa Özbek This is me
Türkiye

Erman Çakal This is me
Türkiye

Publication Date

December 1, 2021

Submission Date

September 11, 2020

Acceptance Date

October 12, 2020

Published in Issue

Year 2021 Volume: 11 Number: 3

IZ

https://izlik.org/JA64GZ93KA

Cite

RIS / Bibtex

APA

Çalapkulu, M., Sencar, M. E., Östürk Ünsal, İ., Sakız, D., Özbek, M., & Çakal, E. (2021). Tek Merkez Deneyimi: Feokromasitoma Olgularının Retrospektif Değerlendirilmesi. Kafkas Journal of Medical Sciences, 11(3), 353-359. https://izlik.org/JA64GZ93KA

AMA

1.Çalapkulu M, Sencar ME, Östürk Ünsal İ, Sakız D, Özbek M, Çakal E. Tek Merkez Deneyimi: Feokromasitoma Olgularının Retrospektif Değerlendirilmesi. Kafkas Journal of Medical Sciences. 2021;11(3):353-359. https://izlik.org/JA64GZ93KA

Chicago

Çalapkulu, Murat, Muhammed Erkam Sencar, İlknur Östürk Ünsal, Davut Sakız, Mustafa Özbek, and Erman Çakal. 2021. “Tek Merkez Deneyimi: Feokromasitoma Olgularının Retrospektif Değerlendirilmesi”. Kafkas Journal of Medical Sciences 11 (3): 353-59. https://izlik.org/JA64GZ93KA.

EndNote

Çalapkulu M, Sencar ME, Östürk Ünsal İ, Sakız D, Özbek M, Çakal E (December 1, 2021) Tek Merkez Deneyimi: Feokromasitoma Olgularının Retrospektif Değerlendirilmesi. Kafkas Journal of Medical Sciences 11 3 353–359.

IEEE

[1]M. Çalapkulu, M. E. Sencar, İ. Östürk Ünsal, D. Sakız, M. Özbek, and E. Çakal, “Tek Merkez Deneyimi: Feokromasitoma Olgularının Retrospektif Değerlendirilmesi”, Kafkas Journal of Medical Sciences, vol. 11, no. 3, pp. 353–359, Dec. 2021, [Online]. Available: https://izlik.org/JA64GZ93KA

ISNAD

Çalapkulu, Murat - Sencar, Muhammed Erkam - Östürk Ünsal, İlknur - Sakız, Davut - Özbek, Mustafa - Çakal, Erman. “Tek Merkez Deneyimi: Feokromasitoma Olgularının Retrospektif Değerlendirilmesi”. Kafkas Journal of Medical Sciences 11/3 (December 1, 2021): 353-359. https://izlik.org/JA64GZ93KA.

JAMA

1.Çalapkulu M, Sencar ME, Östürk Ünsal İ, Sakız D, Özbek M, Çakal E. Tek Merkez Deneyimi: Feokromasitoma Olgularının Retrospektif Değerlendirilmesi. Kafkas Journal of Medical Sciences. 2021;11:353–359.

MLA

Çalapkulu, Murat, et al. “Tek Merkez Deneyimi: Feokromasitoma Olgularının Retrospektif Değerlendirilmesi”. Kafkas Journal of Medical Sciences, vol. 11, no. 3, Dec. 2021, pp. 353-9, https://izlik.org/JA64GZ93KA.

Vancouver

1.Murat Çalapkulu, Muhammed Erkam Sencar, İlknur Östürk Ünsal, Davut Sakız, Mustafa Özbek, Erman Çakal. Tek Merkez Deneyimi: Feokromasitoma Olgularının Retrospektif Değerlendirilmesi. Kafkas Journal of Medical Sciences [Internet]. 2021 Dec. 1;11(3):353-9. Available from: https://izlik.org/JA64GZ93KA